Search Results - "De Haan, A"
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Kinetic analysis of the influenza A virus HA/NA balance reveals contribution of NA to virus-receptor binding and NA-dependent rolling on receptor-containing surfaces
Published in PLoS pathogens (13-08-2018)“…Interactions of influenza A virus (IAV) with sialic acid (SIA) receptors determine viral fitness and host tropism. Binding to mucus decoy receptors and…”
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Mutation of the second sialic acid-binding site of influenza A virus neuraminidase drives compensatory mutations in hemagglutinin
Published in PLoS pathogens (27-08-2020)“…Influenza A viruses (IAVs) cause seasonal epidemics and occasional pandemics. Most pandemics occurred upon adaptation of avian IAVs to humans. This adaptation…”
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ACE-DNV: Automatic classification of gaze events in dynamic natural viewing
Published in Behavior research methods (2024)“…Eye movements offer valuable insights for clinical interventions, diagnostics, and understanding visual perception. The process usually involves recording a…”
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Coronavirus cell entry occurs through the endo-/lysosomal pathway in a proteolysis-dependent manner
Published in PLoS pathogens (01-11-2014)“…Enveloped viruses need to fuse with a host cell membrane in order to deliver their genome into the host cell. While some viruses fuse with the plasma membrane,…”
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Three mutations switch H7N9 influenza to human-type receptor specificity
Published in PLoS pathogens (15-06-2017)“…The avian H7N9 influenza outbreak in 2013 resulted from an unprecedented incidence of influenza transmission to humans from infected poultry. The majority of…”
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Kinetic analysis of paramyxovirus-sialoglycan receptor interactions reveals virion motility
Published in PLoS pathogens (01-03-2023)“…Many viruses initiate infection by binding to sialoglycan receptors at the cell surface. Binding to such receptors comes at a cost, however, as the sheer…”
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Human-type sialic acid receptors contribute to avian influenza A virus binding and entry by hetero-multivalent interactions
Published in Nature communications (13-07-2022)“…Establishment of zoonotic viruses, causing pandemics like the Spanish flu and Covid-19, requires adaptation to human receptors. Pandemic influenza A viruses…”
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Enterovirus D68 receptor requirements unveiled by haploid genetics
Published in Proceedings of the National Academy of Sciences - PNAS (02-02-2016)“…Enterovirus D68 (EV-D68) is an emerging pathogen that can cause severe respiratory disease and is associated with cases of paralysis, especially among…”
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Grading bloodstream infection risk using citrulline as a biomarker of intestinal mucositis in patients receiving intensive therapy
Published in Bone marrow transplantation (Basingstoke) (01-09-2022)“…Earlier studies have suggested that severe intestinal mucositis (IM; citrulline < 10 µmol/L) is an independent risk factor for bloodstream infections (BSI)…”
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Coronavirus nucleocapsid proteins assemble constitutively in high molecular oligomers
Published in Scientific reports (18-07-2017)“…Coronaviruses (CoV) are enveloped viruses and rely on their nucleocapsid N protein to incorporate the positive-stranded genomic RNA into the virions. CoV N…”
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Unraveling dynamics of paramyxovirus-receptor interactions using nanoparticles displaying hemagglutinin-neuraminidase
Published in PLoS pathogens (01-07-2024)“…Sialoglycan-binding enveloped viruses often possess receptor-destroying activity to avoid being immobilized by non-functional decoy receptors. Sialic acid…”
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Development of a Virosomal RSV Vaccine Containing 3D-PHAD® Adjuvant: Formulation, Composition, and Long-Term Stability
Published in Pharmaceutical research (01-09-2018)“…Purpose Characterization of virosomes, in late stage preclinical development as vaccines for Respiratory Syncytial Virus (RSV), with a membrane-incorporated…”
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Selective thiazoline peptide cyclisation compatible with mRNA display and efficient synthesis
Published in Chemical science (Cambridge) (04-10-2023)“…Peptide display technologies are a powerful method for discovery of new bioactive sequences, but linear sequences are often very unstable in a biological…”
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Changes in perceived peripersonal space following the rubber hand illusion
Published in Scientific reports (12-05-2023)“…Peripersonal space (PPS), the region immediately surrounding the body is essential for bodily protection and goal directed action. Previous studies have…”
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Dissection of the influenza A virus endocytic routes reveals macropinocytosis as an alternative entry pathway
Published in PLoS pathogens (01-03-2011)“…Influenza A virus (IAV) enters host cells upon binding of its hemagglutinin glycoprotein to sialylated host cell receptors. Whereas dynamin-dependent,…”
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First international quality control programme for laboratories measuring antimicrobial drugs to support dose individualization in critically ill patients
Published in Journal of antimicrobial chemotherapy (19-01-2021)“…Abstract Objectives International quality control (proficiency testing) programmes are instituted to safeguard the analytical performance of laboratories and…”
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Reduced PTLD-related mortality in patients experiencing EBV infection following allo-SCT after the introduction of a protocol incorporating pre-emptive rituximab
Published in Bone marrow transplantation (Basingstoke) (01-11-2013)“…The mortality associated with post-transplant lymphoproliferative disorder (PTLD) induced by EBV infection can be reduced by monitoring EBV by…”
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Low gH/gL (Sub)Species-Specific Antibody Levels Indicate Elephants at Risk of Fatal Elephant Endotheliotropic Herpesvirus Hemorrhagic Disease
Published in Viruses (01-02-2024)“…Elephant endotheliotropic herpesviruses (EEHVs), of which eleven (sub)species are currently distinguished, infect either Asian ( ) or African elephants (…”
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Direct Binding of Bovine IgG-Containing Immune Complexes to Human Monocytes and Their Putative Role in Innate Immune Training
Published in Nutrients (22-10-2022)“…Bovine milk IgG (bIgG) was shown to bind to and neutralize the human respiratory synovial virus (RSV). In animal models, adding bIgG prevented experimental RSV…”
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Visualizing Coronavirus RNA Synthesis in Time by Using Click Chemistry
Published in Journal of Virology (01-05-2012)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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