Search Results - "De Graan, P.N.E"

Altered synaptic transmission in the hippocampus of transgenic mice with enhanced central nervous systems expression of interleukin-6 by Nelson, T.E, Olde Engberink, A, Hernandez, R, Puro, A, Huitron-Resendiz, S, Hao, C, De Graan, P.N.E, Gruol, D.L

“…Highlight ► Transgenic mice with chronically elevated levels of IL-6 show enhanced excitatory synaptic transmission in the hippocampus…”
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Chronic exposure to the chemokine CCL3 enhances neuronal network activity in rat hippocampal cultures by Kuijpers, M, van Gassen, K.L.I, de Graan, P.N.E, Gruol, D

“…Abstract We examined the effect of chronic CCL3 treatment on the properties of cultured rat hippocampal neurons to gain an understanding of the neuronal…”
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Ontogeny of hippocampal corticosteroid receptors: Effects of antenatal glucocorticoids in human and mouse by Noorlander, C.W., De Graan, P.N.E., Middeldorp, J., Van Beers, J.J.B.C., Visser, G.H.A.

“…Women at risk for preterm delivery are treated with synthetic glucocorticoids (GCs) to enhance fetal lung maturation. GCs can bind to two intracellular…”
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P.3.005 Early environment affects activity based anorexia genetic susceptibility and epigenetic programming of neurodevelopmental genes in mice by Pjetri, E, Hessel, E.V.S, Oppelaar, H, de Graan, P.N.E, Olivier, B, Kas, M.J.H

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Prenatal corticosteroid exposure affects hippocampal plasticity and reduces lifespan by Noorlander, C.W., Visser, G.H.A., Ramakers, G.M.J., Nikkels, P.G.J., de Graan, P.N.E.

“…Synthetic corticosteroids, such as dexamethasone, are frequently administered to pregnant women at risk for preterm delivery. Endogenous corticosteroids are…”
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S.04.01 Identification of a mouse febrile seizure susceptibility gene by Hessel, E.V.S, de Wit, M, Wolterink-Donselaar, I.G, van Lith, H.A, Kas, M.J.H, de Graan, P.N.E

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P.1.014 Identification of a mouse febrile seizure susceptibility gene by Hessel, E.V.S, Kas, M.J.H, van Lith, H.A, Wolterink-Donselaar, I.G, de Wit, M, de Graan, P.N.E

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Increased glutamine synthetase but normal EAAT2 expression in platelets of ALS patients by Bos, I.W.M., Hoogland, G., Meine Jansen, C.F., Willigen, G. van, Spierenburg, H.A., van den Berg, L.H., de Graan, P.N.E.

“…Amyotrophic lateral sclerosis is a fatal neurodegenerative disease and glutamate excitotoxicity has been implicated in its pathogenesis. Platelets contain a…”
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Distribution of Glutamate Transporters in the Human Placenta by Noorlander, C.W., de Graan, P.N.E., Nikkels, P.G.J., Schrama, L.H., Visser, G.H.A.

“…Glutamate metabolism is known to be important for growth and development of the human fetus. The glutamate transporters EAAT1, EAAT2 and EAAT3 are key…”
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A grading system for hippocampal sclerosis based on the degree of hippocampal mossy fiber sprouting by PROPER, E. A, JANSEN, G. H, VAN VEELEN, C. W. M, VAN RIJEN, P. C, GISPEN, W. H, DE GRAAN, P. N. E

“…In patients suffering from temporal lobe epilepsy (TLE) a highly variable degree of hippocampal sclerosis (HS) can be observed. For standard neuropathological…”
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B-50/GAP-43 phosphorylation in hippocampal slices from aged rats: effects of phosphatidylserine administration by Gianotti, C, Porta, A, De Graan, P N, Oestreicher, A B, Nunzi, M G

“…Phosphorylation of the presynaptic protein B-50/GAP-43, a substrate of protein kinase C (PKC), has been implicated in neuronal mechanisms related to learning…”
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The kinase C substrate protein B-50 and axonal regeneration by Verhaagen, J, van Hooff, C O, Edwards, P M, De Graan, P N, Oestreicher, A B, Schotman, P, Jennekens, F G, Gispen, W H

“…As reported previously the prominent protein kinase C substrate protein B-50 is present in growth cones isolated from fetal rat brain and in outgrowing…”
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Microencephaly reduces the phosphorylation of the PKC substrate B-50/GAP43 in rat cortex and hippocampus by Di Luca, M, Cimino, M, De Graan, P N, Oestreicher, A B, Gispen, W H, Cattabeni, F

“…The administration of the antimitotic agent methylazoxymethanol (MAM) to rats at day 15 of gestation results in a consistent loss of intrinsic neurons…”
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Thrombin-stimulated glutamate uptake in human platelets is predominantly mediated by the glial glutamate transporter EAAT2 by Hoogland, G., Bos, I.W.M., Kupper, F., van Willigen, G., Spierenburg, H.A., van Nieuwenhuizen, O., de Graan, P.N.E.

“…Glutamate toxicity has been implicated in the pathogenesis of various neurological diseases. Glial glutamate transporters play a key role in the regulation of…”
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Synaptosomal glutamate and GABA transport in patients with temporal lobe epilepsy by Hoogland, G., Spierenburg, H.A., van Veelen, C.W.M., van Rijen, P.C., van Huffelen, A.C., de Graan, P.N.E.

“…High‐affinity glutamate and GABA transporters found in the plasma membrane of neurons and glial cells terminate neurotransmission by rapidly removing…”
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Alternative splicing of glutamate transporter EAAT2 RNA in neocortex and hippocampus of temporal lobe epilepsy patients by Hoogland, G, van Oort, R.J, Proper, E.A, Jansen, G.H, van Rijen, P.C, van Veelen, C.W.M, van Nieuwenhuizen, O, Troost, D, de Graan, P.N.E

“…Rationale: Altered expression of glutamate transporter EAAT2 protein has been reported in the hippocampus of patients with temporal lobe epilepsy (TLE). Two…”
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Glutamate and ?-aminobutyric acid content and release of synaptosomes from temporal lobe epilepsy patients by Hoogland, G., Hens, J.J.H., De Wit, M., van Veelen, C.W.M., van Huffelen, A.C., Gispen, W.H., de Graan, P.N.E.

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Protein kinase C activity, translocation, and conventional isoforms in aging rat brain by Battaini, Fiorenzo, Elkabes, Stella, Bergamaschi, Stefania, Ladisa, Vito, Lucchi, Laura, De Graan, Pierre N.E., Schuurman, Teunis, Wetsel, William C., Trabucchi, Marco, Govoni, Stefano

“…Protein kinase C was studied in various brain areas in aging Wistar rats. Histone-directed kinase activity from the cortex, hippocampus and cerebellum did not…”
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Long-term potentiation and synaptic protein phosphorylation by Pasinelli, P., Ramakers, G.M.J., Urban, I.J.A., Hens, J.J.H., Oestreicher, A.B., de Graan, P.N.E., Gispen, W.H.

“…Long-term potentiation (LTP) is a well known experimental model for studying the activity-dependent enhancement of synaptic plasticity, and because of its long…”
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Glutamate and γ-aminobutyric acid content and release of synaptosomes from temporal lobe epilepsy patients by Hoogland, G., Hens, J.J.H., De Wit, M., van Veelen, C.W.M., van Huffelen, A.C., Gispen, W.H., de Graan, P.N.E.

“…During surgical intervention in medically refractory temporal lobe epilepsy (TLE) patients, diagnosed with either mesial temporal lobe sclerosis (MTS)‐ or…”
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