Search Results - "De Gonzalo, Chantal V Garcia"
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Structural and mechanistic investigations of protein S-glycosyltransferases
Published in Cell chemical biology (16-12-2021)“…Attachment of sugars to nitrogen and oxygen in peptides is ubiquitous in biology, but glycosylation of sulfur atoms has only been recently described. Here, we…”
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The Glycosyltransferase Involved in Thurandacin Biosynthesis Catalyzes Both O- and S‑Glycosylation
Published in Journal of the American Chemical Society (08-01-2014)“…The S-glycosyltransferase SunS is a recently discovered enzyme that selectively catalyzes the conjugation of carbohydrates to the cysteine thiol of proteins…”
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Structure–Activity Relationships of the S‑Linked Glycocin Sublancin
Published in ACS chemical biology (15-12-2017)“…Sublancin is a 37-amino acid antimicrobial peptide belonging to the glycocin family of natural products. It contains two helices that are held together by two…”
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Investigations into the Mechanism of Action of Sublancin
Published in ACS infectious diseases (08-03-2019)“…Antimicrobial resistance is a global threat that poses a rising concern. One underlying challenge is the limited number of targets in bacteria affected by the…”
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NMR Structure of the S‑Linked Glycopeptide Sublancin 168
Published in ACS chemical biology (21-03-2014)“…Sublancin 168 is a member of a small group of glycosylated antimicrobial peptides known as glycocins. The solution structure of sublancin 168, a 37-amino-acid…”
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Non-proteinogenic Amino Acids in Lacticin 481 Analogues Result in More Potent Inhibition of Peptidoglycan Transglycosylation
Published in ACS chemical biology (16-11-2012)“…Lantibiotics are ribosomally synthesized and post-translationally modified peptide natural products that contain the thioether structures lanthionine and…”
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Mode of action and structure–activity relationship studies of geobacillin I
Published in Journal of antibiotics (01-01-2014)Get full text
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