Search Results - "De Freitas Saito, Renata"

Phosphatidylcholine-Derived Lipid Mediators: The Crosstalk Between Cancer Cells and Immune Cells by Saito, Renata de Freitas, Andrade, Luciana Nogueira de Sousa, Bustos, Silvina Odete, Chammas, Roger

“…To become resistant, cancer cells need to activate and maintain molecular defense mechanisms that depend on an energy trade-off between resistance and…”
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Anticoagulant Activity of Nucleic Acid Nanoparticles (NANPs) Assessed by Thrombin Generation Dynamics on a Fully Automated System by de Freitas Saito, Renata, Barion, Bárbara Gomes, da Rocha, Tania Rubia Flores, Rolband, Alex, Afonin, Kirill A, Chammas, Roger

“…Rapidly reversible anticoagulant agents have great clinical potential. Oligonucleotide-based anticoagulant agents are uniquely positioned to fill this clinical…”
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GD3 ganglioside-enriched extracellular vesicles stimulate melanocyte migration by Otake, Andreia Hanada, de Freitas Saito, Renata, Duarte, Ana Paula Marques, Ramos, Alexandre Ferreira, Chammas, Roger

“…Melanomas often accumulate gangliosides, sialic acid-containing glycosphingolipids found in the outer leaflet of plasma membranes, as disialoganglioside GD3…”
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Phomactinine, the First Nitrogen-Bearing Phomactin, Produced by Biatriospora sp. CBMAI 1333 by da Silva Oliveira, Leandro, Crnkovic, Camila M., de Amorim, Marcelo R., Navarro-Vázquez, Armando, Paz, Tiago A., Freire, Vitor F., Takaki, Mirelle, Venâncio, Tiago, Ferreira, Antonio G., de Freitas Saito, Renata, Chammas, Roger, Berlinck, Roberto G. S.

“…Metabolomics analyses and improvement of growth conditions were applied toward diversification of phomactin terpenoids by the fungus Biatriospora sp. CBMAI…”
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Emerging targets for combination therapy in melanomas by Saito, Renata de Freitas, Tortelli, Tharcísio Citrângulo, Jacomassi, Mayara D’Auria, Otake, Andréia Hanada, Chammas, Roger

“…Cutaneous melanomas are often difficult to treat when diagnosed in advanced stages. Melanoma cells adapt to survive in extreme environmental conditions and are…”
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Galectin-3 sensitized melanoma cell lines to vemurafenib (PLX4032) induced cell death through prevention of autophagy by Bustos, Silvina Odete, da Silva Pereira, Gustavo José, de Freitas Saito, Renata, Gil, Cristiane Damas, Zanatta, Daniela Bertolli, Smaili, Soraya Soubhi, Chammas, Roger

“…Melanoma is a current worldwide problem, as its incidence is increasing. In the last years, several studies have shown that melanoma cells display high levels…”
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Accumulation of prohibitin is a common cellular response to different stressing stimuli and protects melanoma cells from ER stress and chemotherapy-induced cell death by Tortelli, Junior, Tharcisio Citrangulo, de Godoy, Lyris Martins Franco, de Souza, Gustavo Antonio, Bonatto, Diego, Otake, Andreia Hanada, de Freitas Saito, Renata, Rosa, Jose Cesar, Greene, Lewis Joel, Chammas, Roger

“…Melanoma is responsible for most deaths among skin cancers and conventional and palliative care chemotherapy are limited due to the development of…”
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Cracking the Code: Enhancing Molecular Tools for Progress in Nanobiotechnology by Avila, Yelixza I., Rebolledo, Laura P., Skelly, Elizabeth, de Freitas Saito, Renata, Wei, Hui, Lilley, David, Stanley, Robin E., Hou, Ya-Ming, Yang, Haoyun, Sztuba-Solinska, Joanna, Chen, Shi-Jie, Dokholyan, Nikolay V., Tan, Cheemeng, Li, S. Kevin, He, Xiaoming, Zhang, Xiaoting, Miles, Wayne, Franco, Elisa, Binzel, Daniel W., Guo, Peixuan, Afonin, Kirill A.

“…Nature continually refines its processes for optimal efficiency, especially within biological systems. This article explores the collaborative efforts of…”
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Amblyomin-X induces ER stress, mitochondrial dysfunction, and caspase activation in human melanoma and pancreatic tumor cell by Morais, Katia L. P., Pacheco, Mario Thiego Fernandes, Berra, Carolina Maria, Bosch, Rosemary V., Sciani, Juliana Mozer, Chammas, Roger, de Freitas Saito, Renata, Iqbal, Asif, Chudzinski-Tavassi, Ana Marisa

“…During the last two decades, new insights into proteasome function and its role in several human diseases made it a potential therapeutic target. In this…”
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A novel proteasome inhibitor acting in mitochondrial dysfunction, ER stress and ROS production by Maria, Durvanei Augusto, de Souza, Jean Gabriel, Morais, Katia L. P., Berra, Carolina Maria, Zampolli, Hamilton de Campos, Demasi, Marilene, Simons, Simone Michaela, de Freitas Saito, Renata, Chammas, Roger, Chudzinski-Tavassi, Ana Marisa

“…Summary In cancer-treatment, potentially therapeutic drugs trigger their effects through apoptotic mechanisms. Generally, cell response is manifested by Bcl-2…”
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Reestablishment of p53/Arf and interferon-β pathways mediated by a novel adenoviral vector potentiates antiviral response and immunogenic cell death by Hunger, Aline, Medrano, Ruan FV, Zanatta, Daniela B, Del Valle, Paulo R, Merkel, Christian A, Salles, Thiago de Almeida, Ferrari, Daniel G, Furuya, Tatiane K, Bustos, Silvina O, de Freitas Saito, Renata, Costanzi-Strauss, Eugenia, Strauss, Bryan E

“…Late stage melanoma continues to be quite difficult to treat and new therapeutic approaches are needed. Since these tumors often retain wild-type p53 and have…”
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G D3 ganglioside-enriched extracellular vesicles stimulate melanocyte migration by Otake, Andreia Hanada, de Freitas Saito, Renata, Duarte, Ana Paula Marques, Ramos, Alexandre Ferreira, Chammas, Roger

“…Melanomas often accumulate gangliosides, sialic acid-containing glycosphingolipids found in the outer leaflet of plasma membranes, as disialoganglioside G and…”
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Enhanced thrombin generation induced by extracellular vesicles from severe COVID−19 cases by Barion, Bárbara Gomes, Saito, Renata de Freitas, da Rocha, Tania Rubia Flores, Nóbrega, Thaís Dourado Reis, Okazaki, Erica, Ho, Yeh-Li, Villaça, Paula Ribeiro, Rocha, Vanderson Geraldo, Orsi, Fernanda Andrade

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Abstract A73: GD3 ganglioside-enriched extracellular vesicles stimulate melanocyte migration by Otake, Andreia H., Duarte, Ana Paula M., Saito, Renata de Freitas, Ramos, Alexandre F., Chammas, Roger

“…Gangliosides are sialic acid-containing glycosphingolipids located mainly in outlet membrane plasma. Tumors usually accumulate gangliosides as…”
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Abstract A134: Eeyarestatin I sensitizes melanoma cells to cisplatin-induced cell death by Saito, Renata de Freitas, Otake, Andréia Hanada, Cortez, Margarita M., Gillies, Robbert J., Chammas, Roger

“…Melanoma is the most deadly form of skin cancer with a high metastatic potential. Initial stages of the disease can be surgically treated, but the treatment…”
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Abstract A67: Jarid1b protects from metformin-induced chemosensitization to cisplatin through p53 downregulation in NSCLC by Tortelli, Tharcisio Citrangulo, Tamura, Rodrigo Esaki, Tomitao, Michele Tatiana Pereira, Bustos, Silvina Odete, Saito, Renata de Freitas, Leandrini, Sarah Milani de Moraes, Jacomassi, Mayara D'Aurea, Ribeiro, Ulysses, Strauss, Bryan Erik, Chammas, Roger

“…Background: Instead of nontransformed cells, tumor cells use the glycolytic pathway as their main energetic source, even when oxygen is fully available…”
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GD3 ganglioside-enriched extracellular vesicles stimulate melanocyte migration by Otake, Andreia H, Duarte, Ana Paula Marques, Saito, Renata de Freitas, Ramos, Alexandre Ferreira, Chammas, Roger

“…Background: Gangliosides are a family of sialic acid-containing glycosphingolipids that are located mainly in the outer leaflet of plasma membranes…”
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Reestablishment of p53/Arf and interferon-[beta] pathways mediated by a novel adenoviral vector potentiates antiviral response and immunogenic cell death by Hunger, Aline, Medrano, Ruan Fv, Zanatta, Daniela B, Del Valle, Paulo R, Merkel, Christian A, Salles, Thiago De Almeida, Ferrari, Daniel G, Furuya, Tatiane K, Bustos, Silvina O, De Freitas Saito, Renata, Costanzi-strauss, Eugenia, Strauss, Bryan E

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