Search Results - "De Francisco, M. Nuria"

Discovery and optimization of a TRAIL R2 agonist for cancer therapy by Angell, Yvonne M, Bhandari, Ashok, De Francisco, M Nuria, Frederick, Brian T, Green, Jennifer M, Leu, Karen, Leuther, Kerstin, Sana, Reuben, Schatz, Peter J, Whitehorn, Erik A, Wright, Kathy, Holmes, Christopher P

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Discovery and structure–activity relationships of novel sulfonamides as potent PTP1B inhibitors by Holmes, Christopher P., Li, Xianfeng, Pan, Yijun, Xu, Caiding, Bhandari, Ashok, Moody, Claire M., Miguel, Joy A., Ferla, Steven W., De Francisco, M. Nuria, Frederick, Brian T., Zhou, Siqun, Macher, Natalie, Jang, Larry, Irvine, Jennifer D., Grove, J. Russell

“…A series of novel sulfonamides containing a single DFMP group were discovered to be potent inhibitors of PTP1B. Investigation of SAR led to the identification…”
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PTP1B inhibitors: Synthesis and evaluation of difluoro-methylenephosphonate bioisosteres on a sulfonamide scaffold by Holmes, Christopher P., Li, Xianfeng, Pan, Yijun, Xu, Caiding, Bhandari, Ashok, Moody, Claire M., Miguel, Joy A., Ferla, Steven W., De Francisco, M. Nuria, Frederick, Brian T., Zhou, Siqun, Macher, Natalie, Jang, Larry, Irvine, Jennifer D., Grove, J. Russell

“…We have synthesized and evaluated a series of triaryl sulfonamide-based PTP1B inhibitors in which a difluoro-methylenephosphonate group of a potent lead has…”
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