Search Results - "De Felice, Marta"

Reversing the Psychiatric Effects of Neurodevelopmental Cannabinoid Exposure: Exploring Pharmacotherapeutic Interventions for Symptom Improvement by De Felice, Marta, Laviolette, Steven R.

“…Neurodevelopmental exposure to psychoactive compounds in cannabis, specifically THC, is associated with a variety of long-term psychopathological outcomes…”
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Maternal Immune Activation Disrupts Dopamine System in the Offspring by Luchicchi, Antonio, Lecca, Salvatore, Melis, Miriam, De Felice, Marta, Cadeddu, Francesca, Frau, Roberto, Muntoni, Anna Lisa, Fadda, Paola, Devoto, Paola, Pistis, Marco

“…Background: In utero exposure to maternal viral infections is associated with a higher incidence of psychiatric disorders with a supposed neurodevelopmental…”
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Enhanced endocannabinoid-mediated modulation of rostromedial tegmental nucleus drive onto dopamine neurons in Sardinian alcohol-preferring rats by Melis, Miriam, Sagheddu, Claudia, De Felice, Marta, Casti, Alberto, Madeddu, Camilla, Spiga, Saturnino, Muntoni, Anna Lisa, Mackie, Kenneth, Marsicano, Giovanni, Colombo, Giancarlo, Castelli, Maria Paola, Pistis, Marco

“…The progressive predominance of rewarding effects of addictive drugs over their aversive properties likely contributes to the transition from drug use to drug…”
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Sex-specific tonic 2-arachidonoylglycerol signaling at inhibitory inputs onto dopamine neurons of Lister Hooded rats by Melis, Miriam, De Felice, Marta, Lecca, Salvatore, Fattore, Liana, Pistis, Marco

“…Addiction as a psychiatric disorder involves interaction of inherited predispositions and environmental factors. Similarly to humans, laboratory animals…”
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The Impacts of Adolescent Cannabinoid Exposure on Striatal Anxiety- and Depressive-Like Pathophysiology Are Prevented by the Antioxidant N-Acetylcysteine by De Felice, Marta, Szkudlarek, Hanna J., Uzuneser, Taygun C., Rodríguez-Ruiz, Mar, Sarikahya, Mohammed H., Pusparajah, Mathusha, Galindo Lazo, Juan Pablo, Whitehead, Shawn N., Yeung, Ken K.-C., Rushlow, Walter J., Laviolette, Steven R.

“…Exposure to Δ9-tetrahydrocannabinol (THC) is an established risk factor for later-life neuropsychiatric vulnerability, including mood- and anxiety-related…”
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Enhanced serotonin and mesolimbic dopamine transmissions in a rat model of neuropathic pain by Sagheddu, Claudia, Aroni, Sonia, De Felice, Marta, Lecca, Salvatore, Luchicchi, Antonio, Melis, Miriam, Muntoni, Anna Lisa, Romano, Rosaria, Palazzo, Enza, Guida, Francesca, Maione, Sabatino, Pistis, Marco

“…In humans, affective consequences of neuropathic pain, ranging from depression to anxiety and anhedonia, severely impair quality of life and are a major…”
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Repeated exposure to JWH‐018 induces adaptive changes in the mesolimbic and mesocortical dopaminergic pathways, glial cells alterations, and behavioural correlates by Pintori, Nicholas, Castelli, Maria Paola, Miliano, Cristina, Simola, Nicola, Fadda, Paola, Fattore, Liana, Scherma, Maria, Ennas, Maria Grazia, Mostallino, Rafaela, Flore, Giovanna, De Felice, Marta, Sagheddu, Claudia, Pistis, Marco, Di Chiara, Gaetano, De Luca, Maria Antonietta

“…Background and Purpose Spice/K2 herbal mixtures, containing synthetic cannabinoids such as JWH‐018, have been marketed as marijuana surrogates since 2004…”
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PPARα modulation of mesolimbic dopamine transmission rescues depression-related behaviors by Scheggi, Simona, Melis, Miriam, De Felice, Marta, Aroni, Sonia, Muntoni, Anna Lisa, Pelliccia, Teresa, Gambarana, Carla, De Montis, Maria Graziella, Pistis, Marco

“…Depressive disorders cause a substantial burden for the individual and the society. Key depressive symptoms can be modeled in animals and enable the…”
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l-Theanine Prevents Long-Term Affective and Cognitive Side Effects of Adolescent Δ-9-Tetrahydrocannabinol Exposure and Blocks Associated Molecular and Neuronal Abnormalities in the Mesocorticolimbic Circuitry by De Felice, Marta, Renard, Justine, Hudson, Roger, Szkudlarek, Hanna J, Pereira, Brian J, Schmid, Susanne, Rushlow, Walter J, Laviolette, Steven R

“…Chronic adolescent exposure to Δ-9-tetrahydrocannabinol (THC) is linked to elevated neuropsychiatric risk and induces neuronal, molecular and behavioral…”
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The PPARα agonist fenofibrate attenuates disruption of dopamine function in a maternal immune activation rat model of schizophrenia by De Felice, Marta, Melis, Miriam, Aroni, Sonia, Muntoni, Anna Lisa, Fanni, Silvia, Frau, Roberto, Devoto, Paola, Pistis, Marco

“…Summary Aims Prenatal maternal immune activation (MIA) is associated with a risk to develop schizophrenia and affects dopamine systems in the ventral tegmental…”
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THC and CBD produce divergent effects on perception and panic behaviours via distinct cortical molecular pathways by Szkudlarek, Hanna J., Rodríguez-Ruiz, Mar, Hudson, Roger, De Felice, Marta, Jung, Tony, Rushlow, Walter J., Laviolette, Steven R.

“…•Intra-PFC infusion of THC and CBD lead to divergent behavioural and molecular profiles.•THC facilitates panic-like behaviour that can be prevented by…”
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Role of genetic background in the effects of adolescent nicotine exposure on mesolimbic dopamine transmission by Cadoni, Cristina, De Felice, Marta, Corongiu, Silvia, Dessì, Christian, Espa, Elena, Melis, Miriam, Fenu, Sandro

“…Smoking during adolescence may increase the likelihood to develop nicotine dependence and to abuse other drugs such as cocaine. Despite great efforts to…”
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Adolescent Δ-9-tetrahydrocannabinol exposure induces differential acute and long-term neuronal and molecular disturbances in dorsal vs. ventral hippocampal subregions by De Felice, Marta, Chen, Chaochao, Rodríguez-Ruiz, Mar, Szkudlarek, Hanna J, Lam, Michael, Sert, Selvi, Whitehead, Shawn N, Yeung, Ken K-C, Rushlow, Walter J, Laviolette, Steven R

“…Chronic exposure to Δ-9-tetrahydrocannabinol (THC) during adolescence is associated with long-lasting cognitive impairments and enhanced susceptibility to…”
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Prenatal THC exposure induces long-term, sex-dependent cognitive dysfunction associated with lipidomic and neuronal pathology in the prefrontal cortex-hippocampal network by Sarikahya, Mohammed H., Cousineau, Samantha L., De Felice, Marta, Szkudlarek, Hanna J., Wong, Karen K. W., DeVuono, Marieka V., Lee, Kendrick, Rodríguez-Ruiz, Mar, Gummerson, Dana, Proud, Emma, Ng, Tsun Hay Jason, Hudson, Roger, Jung, Tony, Hardy, Daniel B., Yeung, Ken K.-C., Schmid, Susanne, Rushlow, Walter, Laviolette, Steven R.

“…With increasing maternal cannabis use, there is a need to investigate the lasting impact of prenatal exposure to Δ9-tetrahydrocannabinol (THC), the main…”
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Prenatal THC Exposure Induces Sex-Dependent Neuropsychiatric Endophenotypes in Offspring and Long-Term Disruptions in Fatty-Acid Signaling Pathways Directly in the Mesolimbic Circuitry by Sarikahya, Mohammed H, Cousineau, Samantha, De Felice, Marta, Lee, Kendrick, Wong, Karen Kw, DeVuono, Marieka V, Jung, Tony, Rodríguez-Ruiz, Mar, Ng, Tsun Hay Jason, Gummerson, Dana, Proud, Emma, Hardy, Daniel B, Yeung, Ken K-C, Rushlow, Walter, Laviolette, Steven R

“…Despite increased prevalence of maternal cannabis use, little is understood regarding potential long-term effects of prenatal cannabis exposure (PCE) on…”
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REPEATED EXPOSURE TO JWH-018 INDUCES ADAPTIVE CHANGES IN THE MESOLIMBIC AND MESOCORTICAL DOPAMINE PATHWAYS, GLIAL CELLS ALTERATION AND BEHAVIOURAL CORRELATES by Pintori, Nicholas, Castelli, Maria Paola, Miliano, Cristina, Simola, Nicola, Fadda, Paola, Fattore, Liana, Scherma, Maria, Ennas, Maria Grazia, Mostallino, Rafaela, Flore, Giovanna, De Felice, Marta, Sagheddu, Claudia, Pistis, Marco, Di Chiara, Gaetano, De Luca, Maria Antonietta

“…Spice/K2 herbal mixtures, containing synthetic cannabinoids such as JWH-018, have been marketed as marijuana surrogates since 2004. We demonstrated that…”
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