Search Results - "De Felice, F. G"

Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice by Ledo, J H, Azevedo, E P, Clarke, J R, Ribeiro, F C, Figueiredo, C P, Foguel, D, De Felice, F G, Ferreira, S T

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Correction: Amyloid-β oligomers link depressive-like behavior and cognitive deficits in mice by Ledo, J. H., Azevedo, E. P., Clarke, J. R., Ribeiro, F. C., Figueiredo, C. P., Foguel, D., De Felice, F. G., Ferreira, S. T.

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Inhibition of Alzheimer's disease β‐amyloid aggregation, neurotoxicity, and in vivo deposition by nitrophenols: implications for Alzheimer's therapy by Felice, Fernanda G., Houzel, Jean-Christophe, Garcia-Abreu, José, Louzada, Paulo Roberto F., Afonso, Rosenilde C., Meirelles, M. Nazareth L., Lent, Roberto, Neto, Vivaldo Moura, Ferreira, Sérgio T.

“…ABSTRACT Alzheimer's disease (AD) is a major public health problem, and there is currently no clinically accepted treatment to cure it or to stop its…”
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Selective Neoglycosylation Increases the Structural Stability of Vicilin, the 7S Storage Globulin from Pea Seeds by Pedrosa, Cristiana, De Felice, Fernanda G., Trisciuzzi, Cristina, Ferreira, Sérgio T.

“…The effects of glycosylation on the stability and subunit interactions of vicilin, the major storage protein in pea seeds, were investigated. Glycosylated…”
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Stabilization of partially folded states in protein folding/misfolding transitions by hydrostatic pressure by Ferreira, S T, Chapeaurouge, A, De Felice, F G

“…In the last few years, hydrostatic pressure has been extensively used in the study of both protein folding and misfolding/aggregation. Compared to other…”
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Correction: Amyloid-[beta] oligomers link depressive-like behavior and cognitive deficits in mice by Ledo, J. H, Azevedo, E. P, Clarke, J. R, Ribeiro, F. C, Figueiredo, C. P, Foguel, D, De Felice, F. G

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Association of the fibronectin type III domain–containing protein 5 rs1746661 single nucleotide polymorphism with reduced brain glucose metabolism in elderly humans by Lima-Filho, Ricardo A S, Benedet, Andréa L, De Bastiani, Marco Antônio, Povala, Guilherme, Cozachenco, Danielle, Ferreira, Sergio T, De Felice, Fernanda G, Rosa-Neto, Pedro, Zimmer, Eduardo R, Lourenco, Mychael V

“…Abstract Fibronectin type III domain–containing protein 5 (FNDC5) and its derived hormone, irisin, have been associated with metabolic control in humans, with…”
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Amyloid beta oligomers induce impairment of neuronal insulin receptors by Zhao, Wei-Qin, De Felice, Fernanda G, Fernandez, Sara, Chen, Hui, Lambert, Mary P, Quon, Michael J, Krafft, Grant A, Klein, William L

“…Recent studies have indicated an association between Alzheimer's disease (AD) and central nervous system (CNS) insulin resistance. However, the cellular…”
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Amyloid-[beta] oligomers link depressive-like behavior and cognitive deficits in mice by Ledo, J H, Azevedo, E P, Clarke, J R, Ribeiro, F C, Figueiredo, C P, Foguel, D, De Felice, F G, Ferreira, S T

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Memantine Rescues Transient Cognitive Impairment Caused by High-Molecular-Weight A  Oligomers But Not the Persistent Impairment Induced by Low-Molecular-Weight Oligomers by Figueiredo, C. P., Clarke, J. R., Ledo, J. H., Ribeiro, F. C., Costa, C. V., Melo, H. M., Mota-Sales, A. P., Saraiva, L. M., Klein, W. L., Sebollela, A., De Felice, F. G., Ferreira, S. T.

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Subunit dissociation and inactivation of pyruvate kinase by hydrostatic pressure oxidation of sulfhydryl groups and ligand effects on enzyme stability by De Felice, F G, Soares, V C, Ferreira, S T

“…The effect of hydrostatic pressure on the stability of tetrameric rabbit muscle pyruvate kinase was investigated by enzyme activity measurements,…”
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Mitochondrial bound hexokinase activity as a preventive antioxidant defense: steady-state ADP formation as a regulatory mechanism of membrane potential and reactive oxygen species generation in mitochondria by da-Silva, Wagner Seixas, Gómez-Puyou, Armando, de Gómez-Puyou, Marietta Tuena, Moreno-Sanchez, Rafael, De Felice, Fernanda G, de Meis, Leopoldo, Oliveira, Marcus F, Galina, Antonio

“…Brain hexokinase is associated with the outer membrane of mitochondria, and its activity has been implicated in the regulation of ATP synthesis and apoptosis…”
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Targeting the neurotoxic species in Alzheimer's disease: inhibitors of Aβ oligomerization by Felice, Fernanda G., Vieira, Marcelo N. N., Saraiva, Leonardo M., Figueroa‐Villar, J. Daniel, Garcia‐Abreu, JosÉ, Liu, Roy, Chang, Lei, Klein, Willian L., Ferreira, Sergio T.

“…In the past two decades, a large body of evidence has established a causative role for the β‐amy‐loid peptide (Aβ) in Alzheimer's disease (AD). However, recent…”
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PABMB Lecture. Protein dynamics, folding and misfolding: from basic physical chemistry to human conformational diseases by Ferreira, S T, De Felice, F G

“…Proteins exhibit a variety of motions ranging from amino acid side-chain rotations to the motions of large domains. Recognition of their conformational…”
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Activation of GABA A receptors by taurine and muscimol blocks the neurotoxicity of β-amyloid in rat hippocampal and cortical neurons by Paula-Lima, Andréa C., De Felice, Fernanda G., Brito-Moreira, Jordano, Ferreira, Sérgio T.

“…The β-amyloid peptide (Aβ) is centrally related to the pathogenesis of Alzheimer's disease (AD) and is potently neurotoxic to central nervous system neurons…”
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Formation of amyloid aggregates from human lysozyme and its disease‐associated variants using hydrostatic pressure by Felice, Fernanda G. De, Vieira, Marcelo N. N., Meirelles, M. Nazareth L., Morozova‐Roche, Ludmilla A., Dobson, Christopher M., Ferreira, Sérgio T.

“…ABSTRACT Formation of amyloid deposits from the Ile56Thr or Asp67His variants of human lysozyme is a hallmark of autosomal hereditary systemic amyloidosis. It…”
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Beta-amyloid production, aggregation, and clearance as targets for therapy in Alzheimer's disease by De Felice, Fernanda G, Ferreira, Sérgio T

“…1. Despite major efforts aimed at elucidating the molecular basis and physiopathology of Alzheimer's disease (AD), there is still no effective treatment…”
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Protein dynamics, folding and misfolding: from basic physical chemistry to human conformational diseases by Ferreira, Sérgio T, De Felice, Fernanda G

“…Proteins exhibit a variety of motions ranging from amino acid side-chain rotations to the motions of large domains. Recognition of their conformational…”
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Neuritogenesis and neuronal differentiation promoted by 2,4‐dinitrophenol, a novel anti‐amyloidogenic compound by Wasilewska‐Sampaio, Ana Paula, Silveira, Mariana S., Holub, Oliver, Goecking, Rejane, Gomes, Flávia C. A., Neto, Vivaldo Moura, Linden, Rafael, Ferreira, Sérgio T., De Felice, Fernanda G.

“…ABSTRACTNeurite outgrowth is a critical event in neuronal development, formation, and remodeling of synapses, response to injury, and regeneration. We examined…”
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Small molecule inhibitors of lysozyme amyloid aggregation by Vieira, Marcelo N N, Figueroa-Villar, J Daniel, Meirelles, M Nazareth L, Ferreira, Sérgio T, De Felice, Fernanda G

“…Protein amyloid aggregation is associated with a number of important human pathologies, but the precise mechanisms underlying the toxicity of amyloid…”
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