Search Results - "De Fazio, Anna"

IL6-STAT3-HIF Signaling and Therapeutic Response to the Angiogenesis Inhibitor Sunitinib in Ovarian Clear Cell Cancer by ANGLESIO, Michael S, GEORGE, Joshy, CHAKRAVARTY, Probir, GORRINGE, Kylie L, CAMPBELL, Ian G, OKAMOTO, Aikou, BIRRER, Michael J, HUNTSMAN, David G, DE FAZIO, Anna, KALLOGER, Steve E, BALKWILL, Frances, BLAKE GILKS, C, KULBE, Hagen, BOWTELL, David D, FRIEDLANDER, Michael, RISCHIN, Danny, LEMECH, Charlotte, POWER, Jeremy, COWARD, Jermaine, COWIN, Prue A, HOUSE, Colin M

“…Ovarian clear cell adenocarcinoma (OCCA) is an uncommon histotype that is generally refractory to platinum-based chemotherapy. We analyze here the most…”
Get full text

Prediction of Cardiovascular Events by Inflammatory Markers in Patients Undergoing Carotid Stenting by Versaci, Francesco, MD, Reimers, Bernhard, MD, Prati, Francesco, MD, Gaspardone, Achille, MD, PhD, Del Giudice, Costantino, MD, Pacchioni, Andrea, MD, Mauriello, Alessandro, MD, Cortese, Claudio, MD, Nardi, Paolo, MD, De Fazio, Anna, MD, Chiariello, Giovanni Alfonso, MD, Proietti, Igino, MD, Chiariello, Luigi, MD

“…Abstract Objective To assess whether inflammatory markers predict atherosclerotic disease activity after carotid treatment in patients with severe carotid…”
Get full text

Reducing Time to Diagnosis Does Not Improve Outcomes for Women With Symptomatic Ovarian Cancer: A Report From the Australian Ovarian Cancer Study Group by NAGLE, Christina M, FRANCIS, Jane E, NELSON, Anne E, ZORBAS, Helen, LUXFORD, Karen, DE FAZIO, Anna, FEREDAY, Sian, BOWTELL, David D, GREEN, Adèle C, WEBB, Penelope M

“…To determine if time to diagnosis is associated with stage of disease at diagnosis or survival among women with symptomatic ovarian cancer. A representative…”
Get full text

Genome-wide association study of paclitaxel and carboplatin disposition in women with epithelial ovarian cancer by Gao, Bo, Lu, Yi, Nieuweboer, Annemieke J. M., Xu, Hongmei, Beesley, Jonathan, Boere, Ingrid, de Graan, Anne-Joy M., de Bruijn, Peter, Gurney, Howard, J. Kennedy, Catherine, Chiew, Yoke-Eng, Johnatty, Sharon E., Beale, Philip, Harrison, Michelle, Luccarini, Craig, Conroy, Don, Mathijssen, Ron H. J., R. Harnett, Paul, Balleine, Rosemary L., Chenevix-Trench, Georgia, Macgregor, Stuart, de Fazio, Anna

“…Identifying single nucleotide polymorphisms (SNPs) that influence chemotherapy disposition may help to personalize cancer treatment and limit toxicity…”
Get full text

Statin use and survival following a diagnosis of ovarian cancer: A prospective observational study by Majidi, Azam, Na, Renhua, Jordan, Susan J., De Fazio, Anna, Webb, Penelope M.

“…Most women with ovarian cancer have a poor prognosis, but studies have reported an association between statin use and improved survival. We investigated the…”
Get full text

Whole–genome characterization of chemoresistant ovarian cancer by Patch, Ann-Marie, Christie, Elizabeth L., Etemadmoghadam, Dariush, Garsed, Dale W., George, Joshy, Fereday, Sian, Nones, Katia, Cowin, Prue, Alsop, Kathryn, Bailey, Peter J., Kassahn, Karin S., Newell, Felicity, Quinn, Michael C. J., Kazakoff, Stephen, Quek, Kelly, Wilhelm-Benartzi, Charlotte, Curry, Ed, Leong, Huei San, Hamilton, Anne, Mileshkin, Linda, Au-Yeung, George, Kennedy, Catherine, Hung, Jillian, Chiew, Yoke-Eng, Harnett, Paul, Friedlander, Michael, Quinn, Michael, Pyman, Jan, Cordner, Stephen, O’Brien, Patricia, Leditschke, Jodie, Young, Greg, Strachan, Kate, Waring, Paul, Azar, Walid, Mitchell, Chris, Traficante, Nadia, Hendley, Joy, Thorne, Heather, Shackleton, Mark, Miller, David K., Arnau, Gisela Mir, Tothill, Richard W., Holloway, Timothy P., Semple, Timothy, Harliwong, Ivon, Nourse, Craig, Nourbakhsh, Ehsan, Manning, Suzanne, Idrisoglu, Senel, Bruxner, Timothy J. C., Christ, Angelika N., Poudel, Barsha, Holmes, Oliver, Anderson, Matthew, Leonard, Conrad, Lonie, Andrew, Hall, Nathan, Wood, Scott, Taylor, Darrin F., Xu, Qinying, Fink, J. Lynn, Waddell, Nick, Drapkin, Ronny, Stronach, Euan, Gabra, Hani, Brown, Robert, Jewell, Andrea, Nagaraj, Shivashankar H., Markham, Emma, Wilson, Peter J., Ellul, Jason, McNally, Orla, Doyle, Maria A., Vedururu, Ravikiran, Stewart, Collin, Lengyel, Ernst, Pearson, John V., Waddell, Nicola, deFazio, Anna, Grimmond, Sean M., Bowtell, David D. L.

“…Patients with high-grade serous ovarian cancer (HGSC) have experienced little improvement in overall survival, and standard treatment has not advanced beyond…”
Get full text

Pre- and Post-Diagnosis Diet Quality and Ovarian Cancer Survival by Al Ramadhani, Ruqaiya M, Nagle, Christina M, Ibiebele, Torukiri I, Grant, Peter, Friedlander, Michael, DeFazio, Anna, Webb, Penelope M

“…Prior studies evaluating diet quality in relation to ovarian cancer survival are sparse, and to date none have assessed diet quality or diet-quality change…”
Get full text

Voices of women with low-grade serous ovarian cancer: Results from a multinational survey by Sun, Charlotte, Andrews, Nicole, Ludemann, Jane, Larsen, Elsa, MacKay, Clara, de Fazio, Anna, Gaillard, Stephanie, Gourley, Charlie, Carey, Mark, Fader, Amanda, Cunliffe, Heather, Malpica, Anais, Ray-Coquard, Isabelle, Shih, Ie-Ming, Sood, Anil, Vang, Russell, Wong, Kwong, Grisham, Rachel, Banerjee, Susana, Gershenson, David

Get full text

Germline mutation in BRCA1 or BRCA2 and ten-year survival for women diagnosed with epithelial ovarian cancer by Candido-dos-Reis, Francisco J, Song, Honglin, Goode, Ellen L, Cunningham, Julie M, Fridley, Brooke L, Larson, Melissa C, Alsop, Kathryn, Dicks, Ed, Harrington, Patricia, Ramus, Susan J, de Fazio, Anna, Mitchell, Gillian, Fereday, Sian, Bolton, Kelly L, Gourley, Charlie, Michie, Caroline, Karlan, Beth, Lester, Jenny, Walsh, Christine, Cass, Ilana, Olsson, Håkan, Gore, Martin, Benitez, Javier J, Garcia, Maria J, Andrulis, Irene, Mulligan, Anna Marie, Glendon, Gord, Blanco, Ignacio, Lazaro, Conxi, Whittemore, Alice S, McGuire, Valerie, Sieh, Weiva, Montagna, Marco, Alducci, Elisa, Sadetzki, Siegal, Chetrit, Angela, Kwong, Ava, Kjaer, Susanne K, Jensen, Allan, Høgdall, Estrid, Neuhausen, Susan, Nussbaum, Robert, Daly, Mary, Greene, Mark H, Mai, Phuong L, Loud, Jennifer T, Moysich, Kirsten, Toland, Amanda E, Lambrechts, Diether, Ellis, Steve, Frost, Debra, Brenton, James D, Tischkowitz, Marc, Easton, Douglas F, Antoniou, Antonis, Chenevix-Trench, Georgia, Gayther, Simon A, Bowtell, David, Pharoah, Paul D P

“…To analyze the effect of germline mutations in BRCA1 and BRCA2 on mortality in patients with ovarian cancer up to 10 years after diagnosis. We used unpublished…”
Get full text

Cancer sleep symptom‐related phenotypic clustering differs across three cancer specific patient cohorts by Kairaitis, Kristina, Madut, Ayey S., Subramanian, Harini, Trivedi, Ritu, Man, Hong, Mather, Marius, Brand, Alison, Elder, Elisabeth, Howle, Julie, Mann, Graham J, Amis, Terence C., De Fazio, Anna

“…Summary Specific sleep disorders have been linked to disease progression in different cancers. We hypothesised sleep symptom clusters would differ between…”
Get full text

Heritable DNA methylation marks associated with susceptibility to breast cancer by Joo, Jihoon E., Dowty, James G., Milne, Roger L., Wong, Ee Ming, Dugué, Pierre-Antoine, English, Dallas, Hopper, John L., Goldgar, David E., Giles, Graham G., Southey, Melissa C.

“…Mendelian-like inheritance of germline DNA methylation in cancer susceptibility genes has been previously reported. We aimed to scan the genome for heritable…”
Get full text

Population-based targeted sequencing of 54 candidate genes identifies PALB2 as a susceptibility gene for high-grade serous ovarian cancer by Song, Honglin, Dicks, Ed M, Tyrer, Jonathan, Intermaggio, Maria, Chenevix-Trench, Georgia, Bowtell, David D, Traficante, Nadia, Group, Aocs, Brenton, James, Goranova, Teodora, Hosking, Karen, Piskorz, Anna, van Oudenhove, Elke, Doherty, Jen, Harris, Holly R, Rossing, Mary Anne, Duerst, Matthias, Dork, Thilo, Bogdanova, Natalia V, Modugno, Francesmary, Moysich, Kirsten, Odunsi, Kunle, Ness, Roberta, Karlan, Beth Y, Lester, Jenny, Jensen, Allan, Krüger Kjaer, Susanne, Høgdall, Estrid, Campbell, Ian G, Lázaro, Conxi, Pujara, Miguel Angel, Cunningham, Julie, Vierkant, Robert, Winham, Stacey J, Hildebrandt, Michelle, Huff, Chad, Li, Donghui, Wu, Xifeng, Yu, Yao, Permuth, Jennifer B, Levine, Douglas A, Schildkraut, Joellen M, Riggan, Marjorie J, Berchuck, Andrew, Webb, Penelope M, Group, Opal Study, Cybulski, Cezary, Gronwald, Jacek, Jakubowska, Anna, Lubinski, Jan, Alsop, Jennifer, Harrington, Patricia, Chan, Isaac, Menon, Usha, Pearce, Celeste L, Wu, Anna H, de Fazio, Anna, Kennedy, Catherine J, Goode, Ellen, Ramus, Susan, Gayther, Simon, Pharoah, Paul

“…The known epithelial ovarian cancer (EOC) susceptibility genes account for less than 50% of the heritable risk of ovarian cancer suggesting that other…”
Get more information

Genetic Data from Nearly 63,000 Women of European Descent Predicts DNA Methylation Biomarkers and Epithelial Ovarian Cancer Risk by Yang, Yaohua, Wu, Lang, Shu, Xiang, Lu, Yingchang, Shu, Xiao-Ou, Cai, Qiuyin, Beeghly-Fadiel, Alicia, Li, Bingshan, Ye, Fei, Berchuck, Andrew, Anton-Culver, Hoda, Banerjee, Susana, Benitez, Javier, Bjørge, Line, Brenton, James D, Butzow, Ralf, Campbell, Ian G, Chang-Claude, Jenny, Chen, Kexin, Cook, Linda S, Cramer, Daniel W, deFazio, Anna, Dennis, Joe, Doherty, Jennifer A, Dörk, Thilo, Eccles, Diana M, Edwards, Digna Velez, Fasching, Peter A, Fortner, Renée T, Gayther, Simon A, Giles, Graham G, Glasspool, Rosalind M, Goode, Ellen L, Goodman, Marc T, Gronwald, Jacek, Harris, Holly R, Heitz, Florian, Hildebrandt, Michelle A, Høgdall, Estrid, Høgdall, Claus K, Huntsman, David G, Kar, Siddhartha P, Karlan, Beth Y, Kelemen, Linda E, Kiemeney, Lambertus A, Kjaer, Susanne K, Koushik, Anita, Lambrechts, Diether, Le, Nhu D, Levine, Douglas A, Massuger, Leon F, Matsuo, Keitaro, May, Taymaa, McNeish, Iain A, Menon, Usha, Modugno, Francesmary, Monteiro, Alvaro N, Moorman, Patricia G, Moysich, Kirsten B, Ness, Roberta B, Nevanlinna, Heli, Olsson, Håkan, Onland-Moret, N Charlotte, Park, Sue K, Paul, James, Pearce, Celeste L, Pejovic, Tanja, Phelan, Catherine M, Pike, Malcolm C, Ramus, Susan J, Riboli, Elio, Rodriguez-Antona, Cristina, Romieu, Isabelle, Sandler, Dale P, Schildkraut, Joellen M, Setiawan, Veronica W, Shan, Kang, Siddiqui, Nadeem, Sieh, Weiva, Stampfer, Meir J, Sutphen, Rebecca, Swerdlow, Anthony J, Szafron, Lukasz M, Teo, Soo Hwang, Tworoger, Shelley S, Tyrer, Jonathan P, Webb, Penelope M, Wentzensen, Nicolas, White, Emily, Willett, Walter C, Wolk, Alicja, Woo, Yin Ling, Wu, Anna H, Yan, Li, Yannoukakos, Drakoulis, Chenevix-Trench, Georgia, Sellers, Thomas A, Pharoah, Paul D P, Zheng, Wei, Long, Jirong

“…DNA methylation is instrumental for gene regulation. Global changes in the epigenetic landscape have been recognized as a hallmark of cancer. However, the role…”
Get full text

Ovarian cancer pathology characteristics as predictors of variant pathogenicity in BRCA1 and BRCA2 by O’Mahony, Denise G., Ramus, Susan J., Southey, Melissa C., Meagher, Nicola S., Hadjisavvas, Andreas, John, Esther M., Hamann, Ute, Imyanitov, Evgeny N., Andrulis, Irene L., Sharma, Priyanka, Daly, Mary B., Hake, Christopher R., Weitzel, Jeffrey N., Jakubowska, Anna, Godwin, Andrew K., Arason, Adalgeir, Bane, Anita, Simard, Jacques, Soucy, Penny, Caligo, Maria A., Mai, Phuong L., Claes, Kathleen B. M., Teixeira, Manuel R., Chung, Wendy K., Lazaro, Conxi, Hulick, Peter J., Toland, Amanda E., Pedersen, Inge Sokilde, Neuhausen, Susan L., Vega, Ana, de la Hoya, Miguel, Nevanlinna, Heli, Dhawan, Mallika, Zampiga, Valentina, Danesi, Rita, Varesco, Liliana, Gismondi, Viviana, Vellone, Valerio Gaetano, James, Paul A., Janavicius, Ramunas, Nikitina-Zake, Liene, Nielsen, Finn Cilius, van Overeem Hansen, Thomas, Pejovic, Tanja, Borg, Ake, Rantala, Johanna, Offit, Kenneth, Montagna, Marco, Nathanson, Katherine L., Domchek, Susan M., Osorio, Ana, García, María J., Karlan, Beth Y., De Fazio, Anna, Bowtell, David, McGuffog, Lesley, Leslie, Goska, Parsons, Michael T., Dörk, Thilo, Speith, Lisa-Marie, dos Santos, Elizabeth Santana, da Costa, Alexandre André B. A., Radice, Paolo, Peterlongo, Paolo, Papi, Laura, Engel, Christoph, Hahnen, Eric, Schmutzler, Rita K., Wappenschmidt, Barbara, Easton, Douglas F., Tischkowitz, Marc, Singer, Christian F., Tan, Yen Yen, Whittemore, Alice S., Sieh, Weiva, Brenton, James D., Yannoukakos, Drakoulis, Fostira, Florentia, Konstantopoulou, Irene, Soukupova, Jana, Vocka, Michal, Chenevix-Trench, Georgia, Pharoah, Paul D. P., Antoniou, Antonis C., Goldgar, David E., Spurdle, Amanda B., Michailidou, Kyriaki

“…Background The distribution of ovarian tumour characteristics differs between germline BRCA1 and BRCA2 pathogenic variant carriers and non-carriers. In this…”
Get full text

Circulating 25-hydroxyvitamin D and survival in women with ovarian cancer by Webb, Penelope M, de Fazio, Anna, Protani, Melinda M, Ibiebele, Torukiri I, Nagle, Christina M, Brand, Alison H, Blomfield, Penelope I, Grant, Peter, Perrin, Lewis C, Neale, Rachel E

“…Background: Vitamin D status might be associated with cancer survival. Survival after ovarian cancer is poor, but the association with vitamin D has rarely…”
Get full text

Refined cut-off for TP53 immunohistochemistry improves prediction of TP53 mutation status in ovarian mucinous tumors: implications for outcome analyses by Cheasley, Dane, da Cunha Torres, Michelle, Salazar, Carolina, Xing, Zhongyue, Mes-Masson, Anne-Marie, Provencher, Diane M., Rahimi, Kurosh, Fasching, Peter A., Goodman, Marc T., Deen, Suha, Sieh, Weiva, Mateoiu, Constantina, Cook, Linda S., Le, Nhu D., Anglesio, Michael S., Chenevix-Trench, G., Traficante, N., Harrap, K., Sadkowsky, T., Mellon, A., Jones, M., Green, L., Ranieri, B., White, J., Bowes, L., Galletta, L., Giles, D., Hendley, J., Alsop, K., Young, C., Viduka, S., Glavinas, Lydia, Rutovitz, J., Glasgow, A., Bonaventura, T., Begbie, S., Baron-Hay, S., Nevell, D., Valmadre, S., Marsden, D., Beale, P., Beith, J., Carter, J., Dalrymple, C., Brand, A., Byth, K., Jaworski, R., Papadimos, D., Crandon, A., Cummings, M., Horwood, K., Perrin, L., Wyld, D., Davy, M., Oehler, M.K., Hall, C., Henderson, D., Miller, J., Blomfield, P., Rome, R., Grant, P., Laurie, R., Robbie, M., Manolitsas, T., McNealage, J., Susil, B., Sumithran, E., Phillips, K., Rischin, D., Fox, S., Loughrey, M., Billson, V., Neesham, D., Quinn, M., Blum, R., Leung, Y., Buck, M., Purdie, D., Ramus, Susan J., Scott, Clare L., Köbel, Martin, Gorringe, Kylie L., Allan, Prue E., Böhm, Maret, Christie, Michael, DeFazio, Anna, Fairweather, Nicole, Hadley, Alison M., Hendley, Joy, Ho, Gwo-Yaw, Huntsman, David G., Jobling, Tom W., Kennedy, Catherine J., Le Page, Cecile, Pyman, Jan, Rahimi, Kurosh, Samimi, Goli, Sharma, Ragwha, Antill, Yoland C., Gorringe, Kylie L.

“…TP53 mutations are implicated in the progression of mucinous borderline tumors (MBOT) to mucinous ovarian carcinomas (MOC). Optimized immunohistochemistry…”
Get full text

The RING finger domain E3 ubiquitin ligases BRCA1 and the RNF20/RNF40 complex in global loss of the chromatin mark histone H2B monoubiquitination (H2Bub1) in cell line models and primary high-grade serous ovarian cancer by Dickson, Kristie-Ann, Cole, Alexander J, Gill, Anthony J, Clarkson, Adele, Gard, Gregory B, Chou, Angela, Kennedy, Catherine J, Henderson, Beric R, Fereday, Sian, Traficante, Nadia, Alsop, Kathryn, Bowtell, David D, deFazio, Anna, Clifton-Bligh, Roderick, Marsh, Deborah J

“…Enzymatic factors driving cancer-associated chromatin remodelling are of increasing interest as the role of the cancer epigenome in gene expression and DNA…”
Get full text

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer by Winham, Stacey J., Traficante, Nadia, Tołoczko, Aleksandra, Tiezzi, Daniel G., Sinn, Peter, Rothstein, Joseph H., Paz-Ares, Luis, Oszurek, Oleg, Orsulic, Sandra, Nelson, Gregg, Menkiszak, Janusz, Longacre, Teri A., Li, Zheng, Lester, Jenny, Kennedy, Catherine J., Kalli, Kimberly R., Johnatty, Sharon E., Jensen, Allan, Hung, Jillian, Herpel, Esther, Hernandez, Brenda Y., Hartkopf, Andreas D., de Andrade, Jurandyr M., Chudecka-Głaz, Anita, Brucker, Sara Y., Bowtell, D., Webb, P., Gertig, D., Fereday, S., Moore, S., Harrap, K., Pandeya, N., Malt, M., Mellon, A., Robertson, R., Vanden Bergh, T., Brown, S., Green, L., Ferguson, K., Martyn, A., Ball, C., Bilic, Sanela, Stuart-Harris, R., Glasgow, A., Proietto, A., Braye, S., Shannon, J., Ferrier, A., Nevell, D., Valmadre, S., Young, B., Crouch, R., Robertson, G., Carter, J., Dalrymple, C., Houghton, R., Grygiel, J., Jaworski, R., Harnett, P., Wain, G., Papadimos, D., Crandon, A., Cummings, M., Horwood, K., Obermair, A., Davy, M., Dodd, T., Henderson, D., Pierdes, J., Brown, B., Allen, D., Grant, P., Robbie, M., Healy, D., Jobling, T., McNealage, J., Fox, S., Lade, S., Loughrey, M., O'Callaghan, N., Murray, W., Neesham, D., Bell, R., Ganju, V., Buck, M., Whiteman, D., Whittemore, Alice S., Steed, Helen, Kjaer, Susanne K., Kelemen, Linda E., Karlan, Beth Y., Huntsman, David G., Høgdall, Estrid, Gronwald, Jacek, Fasching, Peter A., Chang-Claude, Jenny, Campbell, Ian G., Pharoah, Paul D.P., Ramus, Susan J., Goode, Ellen L.

“…To evaluate myeloid differentiation primary response gene 88 (MyD88) and Toll-like receptor 4 (TLR4) expression in relation to clinical features of epithelial…”
Get full text

Abstract 4616: Chemo-sensitisation in epithelial ovarian cancer cell lines by targeting Ankyrin Repeat Domain 1 (ANKRD1) by Lei, Ying, Henderson, Beric Ross, Emmanuel, Catherine, Harnett, Paul, Fazio, Anna de

“…Abstract Primary and acquired chemotherapy resistance remains a major challenge in the treatment of epithelial ovarian cancer and there are currently few…”
Get full text

Recreational physical inactivity and mortality in women with invasive epithelial ovarian cancer: evidence from the Ovarian Cancer Association Consortium by Cannioto, Rikki A, LaMonte, Michael J, Kelemen, Linda E, Risch, Harvey A, Eng, Kevin H, Minlikeeva, Albina N, Hong, Chi-Chen, Szender, J Brian, Sucheston-Campbell, Lara, Joseph, Janine M, Berchuck, Andrew, Chang-Claude, Jenny, Cramer, Daniel W, DeFazio, Anna, Diergaarde, Brenda, Dörk, Thilo, Doherty, Jennifer A, Edwards, Robert P, Fridley, Brooke L, Friel, Grace, Goode, Ellen L, Goodman, Marc T, Hillemanns, Peter, Hogdall, Estrid, Hosono, Satoyo, Kelley, Joseph L, Kjaer, Susanne K, Klapdor, Rüdiger, Matsuo, Keitaro, Odunsi, Kunle, Nagle, Christina M, Olsen, Catherine M, Paddock, Lisa E, Pearce, Celeste L, Pike, Malcolm C, Rossing, Mary A, Schmalfeldt, Barbara, Segal, Brahm H, Szamreta, Elizabeth A, Thompson, Pamela J, Tseng, Chiu-Chen, Vierkant, Robert, Schildkraut, Joellen M, Wentzensen, Nicolas, Wicklund, Kristine G, Winham, Stacey J, Wu, Anna H, Modugno, Francesmary, Ness, Roberta B, Jensen, Allan, Webb, Penelope M, Terry, Kathryn, Bandera, Elisa V, Moysich, Kirsten B

“…Background: Little is known about modifiable behaviours that may be associated with epithelial ovarian cancer (EOC) survival. We conducted a pooled analysis of…”
Get full text