Search Results - "De Craen, M."

Handgrip strength as a predictor of functional, psychological and social health. A prospective population-based study among the oldest old by Taekema, Diana G., Gussekloo, Jacobijn, Maier, Andrea B., Westendorp, Rudi G. J., de Craen, Anton J. M.

“…Background: muscle wasting is associated with a detrimental outcome in older people. Muscle strength measurements could be useful as part of a clinical…”
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Cerebral blood flow in small vessel disease: A systematic review and meta-analysis by Shi, Yulu, Thrippleton, Michael J, Makin, Stephen D, Marshall, Ian, Geerlings, Mirjam I, de Craen, Anton JM, van Buchem, Mark A, Wardlaw, Joanna M

“…White matter hyperintensities are frequent on neuroimaging of older people and are a key feature of cerebral small vessel disease. They are commonly attributed…”
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Impact of physical and mental health on life satisfaction in old age: a population based observational study by Puvill, Thomas, Lindenberg, Jolanda, de Craen, Antonius J M, Slaets, Joris P J, Westendorp, Rudi G J

“…It is widely assumed that poor health lowers life satisfaction when ageing. Yet, research suggests this relationship is not straightforward. This study…”
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Subclinical Thyroid Dysfunction and the Risk of Heart Failure in Older Persons at High Cardiovascular Risk by Nanchen, David, Gussekloo, Jacobijn, Westendorp, Rudi G. J, Stott, David J, Jukema, J. Wouter, Trompet, Stella, Ford, Ian, Welsh, Paul, Sattar, Naveed, Macfarlane, Peter W, Mooijaart, Simon P, Rodondi, Nicolas, de Craen, Anton J. M, on behalf of the PROSPER Group

“…Context: Subclinical thyroid dysfunction is common in older people. However, its clinical importance is uncertain. Objective: Our objective was to determine…”
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Blood pressure and 10-year mortality risk in the Milan Geriatrics 75+ Cohort Study: role of functional and cognitive status by Ogliari, Giulia, Westendorp, Rudi G J, Muller, Majon, Mari, Daniela, Torresani, Erminio, Felicetta, Irene, Lucchi, Tiziano, Rossi, Paolo D, Sabayan, Behnam, de Craen, Anton J M

“…Optimal blood pressure targets in older adults are controversial. to investigate whether the relation of blood pressure with mortality in older adults varies…”
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Systemic Markers of Inflammation and Cognitive Decline in Old Age by Schram, Miranda T., Euser, Sjoerd M., De Craen, Anton J. M., Witteman, Jacqueline C., Frölich, Marijke, Hofman, Albert, Jolles, Jelle, Breteler, Monique M. B., Westendorp, Rudi G. J.

“…OBJECTIVES: To investigate whether higher circulating levels of C‐reactive protein (CRP), interleukin‐6 (IL‐6), and α1‐antichymotrypsin (ACT) are associated…”
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Characteristics of randomized controlled trials designed for elderly: a systematic review by Broekhuizen, Karen, Pothof, Axel, de Craen, Anton J M, Mooijaart, Simon P

“…To quantify the proportion of randomized controlled trials (RCTs) specifically designed for elderly, and to assess their characteristics, as compared to RCTs…”
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Temporal relationship between handgrip strength and cognitive performance in oldest old people by Taekema, Diana G, Ling, Carolina H Y, Kurrle, Susan E, Cameron, Ian D, Meskers, Carel G M, Blauw, Gerard J, Westendorp, Rudi G J, de Craen, Anton J M, Maier, Andrea B

“…cognitive decline and muscle weakness are prevalent health conditions in elderly people. We hypothesised that cognitive decline precedes muscle weakness. to…”
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Associations between age and gray matter volume in anatomical brain networks in middle‐aged to older adults by Hafkemeijer, Anne, Altmann‐Schneider, Irmhild, Craen, Anton J. M., Slagboom, P. Eline, Grond, Jeroen, Rombouts, Serge A. R. B.

“…Summary Aging is associated with cognitive decline, diminished brain function, regional brain atrophy, and disrupted structural and functional brain…”
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Postoperative complications and survival of elderly breast cancer patients: a FOCUS study analysis by de Glas, N. A., Kiderlen, M., Bastiaannet, E., de Craen, A. J. M., van de Water, W., van de Velde, C. J. H., Liefers, G. J.

“…Old age is associated with comorbidity and decreased functioning which influences treatment decisions in elderly breast cancer patients. The purpose of this…”
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Prediction of functional decline in community-dwelling older persons in general practice: a cohort study by van Blijswijk, Sophie C E, Blom, Jeanet W, de Craen, Anton J M, den Elzen, Wendy P J, Gussekloo, Jacobijn

“…A first step to offer community-dwelling older persons proactive care is to identify those at risk of functional decline within a year. This study investigates…”
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Hallmark features of immunosenescence are absent in familial longevity by Derhovanessian, Evelyna, Maier, Andrea B, Beck, Robert, Jahn, Gerhard, Hähnel, Karin, Slagboom, P Eline, de Craen, Anton J M, Westendorp, Rudi G J, Pawelec, Graham

“…Seropositivity for CMV is one of the parameters of the "immune risk profile" associated with mortality in longitudinal studies of the very elderly and may…”
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Genome-wide association study (GWAS)-identified disease risk alleles do not compromise human longevity by Beekman, Marian, Nederstigt, Christa, Suchiman, H. Eka D., Kremer, Dennis, van der Breggen, Ruud, Lakenberg, Nico, Alemayehu, Wendimagegn Ghidey, de Craen, Anton J. M., Westendorp, Rudi G. J., Boomsma, Dorret I., de Geus, Eco J. C., Houwing-Duistermaat, Jeanine J., Heijmans, Bastiaan T., Slagboom, P. Eline, Cantor, Charles R.

“…A set of currently known alleles increasing the risk for coronary artery disease, cancer, and type 2 diabetes as identified by genome-wide association studies…”
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Unraveling the Directional Link between Adiposity and Inflammation: A Bidirectional Mendelian Randomization Approach by Welsh, Paul, Polisecki, Eliana, Robertson, Michele, Jahn, Sabine, Buckley, Brendan M, de Craen, Anton J. M, Ford, Ian, Jukema, J. Wouter, Macfarlane, Peter W, Packard, Chris J, Stott, David J, Westendorp, Rudi G. J, Shepherd, James, Hingorani, Aroon D, Smith, George Davey, Schaefer, Ernst, Sattar, Naveed

“…Context: Associations between adiposity and circulating inflammation markers are assumed to be causal, although the direction of the relationship has not been…”
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Blood pressure variability and cardiovascular risk in the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) by Poortvliet, Rosalinde K E, Ford, Ian, Lloyd, Suzanne M, Sattar, Naveed, Mooijaart, Simon P, de Craen, Anton J M, Westendorp, Rudi G J, Jukema, J Wouter, Packard, Christopher J, Gussekloo, Jacobijn, de Ruijter, Wouter, Stott, David J

“…Variability in blood pressure predicts cardiovascular disease in young- and middle-aged subjects, but relevant data for older individuals are sparse. We…”
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Subclinical thyroid dysfunction and cognitive decline in old age by Wijsman, Liselotte W, de Craen, Anton J M, Trompet, Stella, Gussekloo, Jacobijn, Stott, David J, Rodondi, Nicolas, Welsh, Paul, Jukema, J Wouter, Westendorp, Rudi G J, Mooijaart, Simon P

“…Subclinical thyroid dysfunction has been implicated as a risk factor for cognitive decline in old age, but results are inconsistent. We investigated the…”
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Long-term effects of statin treatment in elderly people: extended follow-up of the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) by Lloyd, Suzanne M, Stott, David J, de Craen, Anton J M, Kearney, Patricia M, Sattar, Naveed, Perry, Ivan, Packard, Christopher J, Briggs, Andrew, Marchbank, Laura, Comber, Harry, Jukema, J Wouter, Westendorp, Rudi G J, Trompet, Stella, Buckley, Brendan M, Ford, Ian

“…The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER), a placebo-controlled trial of pravastatin, demonstrated a 19% reduction in coronary…”
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Meta-Analysis of Nonsteroidal Antiinflammatory Drug Use and Risk of Dementia by de Craen, Anton J. M., Gussekloo, Jacobijn, Vrijsen, Bram, Westendorp, Rudi G. J.

“…The authors performed a systematic review to summarize the epidemiologic evidence on the association between use of nonsteroidal antiinflammatory drugs…”
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Apolipoprotein E Genotype, Plasma Cholesterol, and Cancer: A Mendelian Randomization Study by Trompet, Stella, Jukema, J. Wouter, Katan, Martijn B., Blauw, Gerard J., Sattar, Naveed, Buckley, Brendan, Caslake, Muriel, Ford, Ian, Shepherd, Jim, Westendorp, Rudi G. J., de Craen, Anton J. M.

“…Observational studies have shown an association between low plasma cholesterol levels and increased risk of cancer, whereas most randomized clinical trials…”
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Associations of Various Health-Ratings with Geriatric Giants, Mortality and Life Satisfaction in Older People by Puvill, Thomas, Lindenberg, Jolanda, Gussekloo, Jacobijn, de Craen, Anton J M, Slaets, Joris P J, Westendorp, Rudi G J

“…Self-rated health is routinely used in research and practise among general populations. Older people, however, seem to change their health perceptions. To…”
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