Search Results - "De Chassey, Benoit"
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The interactomes of influenza virus NS1 and NS2 proteins identify new host factors and provide insights for ADAR1 playing a supportive role in virus replication
Published in PLoS pathogens (01-07-2013)“…Influenza A NS1 and NS2 proteins are encoded by the RNA segment 8 of the viral genome. NS1 is a multifunctional protein and a virulence factor while NS2 is…”
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Elucidating Novel Hepatitis C Virus–Host Interactions Using Combined Mass Spectrometry and Functional Genomics Approaches
Published in Molecular & cellular proteomics (01-01-2014)“…More than 170 million people worldwide are infected with the hepatitis C virus (HCV), for which future therapies are expected to rely upon a combination of…”
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An anti-diabetic drug targets NEET (CISD) proteins through destabilization of their [2Fe-2S] clusters
Published in Communications biology (10-05-2022)“…Elevated levels of mitochondrial iron and reactive oxygen species (ROS) accompany the progression of diabetes, negatively impacting insulin production and…”
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VirHostNet: a knowledge base for the management and the analysis of proteome-wide virus-host interaction networks
Published in Nucleic acids research (01-01-2009)“…Infectious diseases caused by viral agents kill millions of people every year. The improvement of prevention and treatment of viral infections and their…”
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Mitochondrial morphodynamics alteration induced by influenza virus infection as a new antiviral strategy
Published in PLoS pathogens (01-02-2021)“…Influenza virus infections are major public health threats due to their high rates of morbidity and mortality. Upon influenza virus entry, host cells…”
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Virus-host interactomics: new insights and opportunities for antiviral drug discovery
Published in Genome medicine (29-11-2014)“…The current therapeutic arsenal against viral infections remains limited, with often poor efficacy and incomplete coverage, and appears inadequate to face the…”
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Viruses and Interactomes in Translation
Published in Molecular & cellular proteomics (01-07-2012)“…A decade of high-throughput screenings for intraviral and virus-host protein-protein interactions led to the accumulation of data and to the development of…”
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Chemical targeting of NEET proteins reveals their function in mitochondrial morphodynamics
Published in EMBO reports (03-12-2020)“…Several human pathologies including neurological, cardiac, infectious, cancerous, and metabolic diseases have been associated with altered mitochondria…”
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Correction: Mitochondrial morphodynamics alteration induced by influenza virus infection as a new antiviral strategy
Published in PLoS pathogens (31-03-2021)“…[This corrects the article DOI: 10.1371/journal.ppat.1009340.]…”
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Structure homology and interaction redundancy for discovering virus-host protein interactions
Published in EMBO reports (01-10-2013)“…Virus–host interactomes are instrumental to understand global perturbations of cellular functions induced by infection and discover new therapies. The…”
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New horizons for antiviral drug discovery from virus–host protein interaction networks
Published in Current opinion in virology (01-10-2012)“…► Human proteins interacting with viruses are a vast reservoir of new antiviral targets. ► Orthogonal ‘-omics’ approaches provide a rational to select relevant…”
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Genetic screens for the control of influenza virus replication: from meta-analysis to drug discovery
Published in Molecular bioSystems (01-04-2012)“…Current anti-influenza virus drugs target two viral proteins and induce a selective pressure for the generation of drug resistant variants. This stresses the…”
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The Interactomes of Influenza Virus NS1 and NS2 Proteins Identify New Host Factors and Provide Insights for ADAR1 Playing a Supportive Role in Virus Replication: e1003440
Published in PLoS pathogens (01-07-2013)“…Influenza A NS1 and NS2 proteins are encoded by the RNA segment 8 of the viral genome. NS1 is a multifunctional protein and a virulence factor while NS2 is…”
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Membrane sorting in the endocytic and phagocytic pathway of Dictyostelium discoideum
Published in European journal of cell biology (01-12-2001)“…To study sorting in the endocytic pathway of a phagocytic and macropinocytic cell, monoclonal antibodies to membrane proteins of Dictyostelium discoideum were…”
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pISTil: a pipeline for yeast two-hybrid Interaction Sequence Tags identification and analysis
Published in BMC research notes (29-10-2009)“…High-throughput screening of protein-protein interactions opens new systems biology perspectives for the comprehensive understanding of cell physiology in…”
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Nucleolin interacts with influenza A nucleoprotein and contributes to viral ribonucleoprotein complexes nuclear trafficking and efficient influenza viral replication
Published in Scientific reports (04-07-2016)“…Influenza viruses replicate their single-stranded RNA genomes in the nucleus of infected cells and these replicated genomes (vRNPs) are then exported from the…”
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5399 VONAFEXOR AS A NOVEL THERAPY FOR CHRONIC KIDNEY DISEASE
Published in Nephrology, dialysis, transplantation (14-06-2023)Get full text
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