Search Results - "De Castro, María J"

Characterization of New Proteomic Biomarker Candidates in Mucopolysaccharidosis Type IVA by Álvarez, Víctor J, Bravo, Susana B, Chantada-Vazquez, Maria Pilar, Colón, Cristóbal, De Castro, María J, Morales, Montserrat, Vitoria, Isidro, Tomatsu, Shunji, Otero-Espinar, Francisco J, Couce, María L

“…Mucopolysaccharidosis type IVA (MPS IVA) is a lysosomal storage disease caused by mutations in the -acetylgalactosamine-6-sulfatase ( ) gene. Skeletal…”
Get full text

Proteomic Analysis in Morquio A Cells Treated with Immobilized Enzymatic Replacement Therapy on Nanostructured Lipid Systems by Álvarez, J Víctor, Bravo, Susana B, García-Vence, María, De Castro, María J, Luzardo, Asteria, Colón, Cristóbal, Tomatsu, Shunji, Otero-Espinar, Francisco J, Couce, María L

“…Morquio A syndrome, or mucopolysaccharidosis type IVA (MPS IVA), is a lysosomal storage disease due to mutations in the N-acetylgalactosamine-6-sulfatase ( )…”
Get full text

Does Diagnostic Classification of Early-Onset Psychosis Change Over Follow-Up? by Fraguas, David, de Castro, María J., Medina, Oscar, Parellada, Mara, Moreno, Dolores, Graell, Montserrat, Merchán-Naranjo, Jessica, Arango, Celso

“…Objective To examine the diagnostic stability and the functional outcome of patients with early-onset psychosis (EOP) over a 2-year follow-up period. Methods A…”
Get full text

A phase I/II study on intracerebroventricular tralesinidase alfa in patients with Sanfilippo syndrome type B by Muschol, Nicole, Koehn, Anja, von Cossel, Katharina, Okur, Ilyas, Ezgu, Fatih, Harmatz, Paul, de Castro Lopez, Maria J, Couce, Maria Luz, Lin, Shuan-Pei, Batzios, Spyros, Cleary, Maureen, Solano, Martha, Nestrasil, Igor, Kaufman, Brian, Shaywitz, Adam J, Maricich, Stephen M, Kuca, Bernice, Kovalchin, Joseph, Zanelli, Eric

“…BackgroundSanfilippo type B is a mucopolysaccharidosis (MPS) with a major neuronopathic component characterized by heparan sulfate (HS) accumulation due to…”
Get full text

QTc changes after 6 months of second-generation antipsychotic treatment in children and adolescents by de Castro, María J, Fraguas, David, Laita, Paula, Moreno, Dolores, Parellada, Mara, Pascual, David, Alvarez, Mar, Merchán-Naranjo, Jessica, Rapado, Marta, Giráldez, Marisa, Leiva, Marta, Arango, Celso

Get more information

25 de Abril Sempre! Portuguese Science and the 50th anniversary of the Carnation Revolution by Dantas, Tiago, Abreu, Carla M. C., De-Castro, Maria J. G., Grosso, Ana Rita, de Sousa Valente, Joao, da Silva Xavier, Gabriela

Get full text

Building train carriages for ciliary transport: (IFT-)A complex task by Gonçalves-Santos, Francisco, De-Castro, Maria J. G., De-Castro, Ana R. G., Dantas, Tiago J.

“…Cilia assembly and function require intraflagellar transport (IFT), a mechanism that uses “trains” to transport cargoes into and out of cilia. While much has…”
Get full text

WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing by De-Castro, Ana R G, Rodrigues, Diogo R M, De-Castro, Maria J G, Vieira, Neide, Vieira, Cármen, Carvalho, Ana X, Gassmann, Reto, Abreu, Carla M C, Dantas, Tiago J

“…The dynein-2 motor complex drives retrograde intraflagellar transport (IFT), playing a pivotal role in the assembly and functions of cilia. However, the…”
Get full text

Hot-wiring dynein-2 establishes roles for IFT-A in retrograde train assembly and motility by Gonçalves-Santos, Francisco, De-Castro, Ana R.G., Rodrigues, Diogo R.M., De-Castro, Maria J.G., Gassmann, Reto, Abreu, Carla M.C., Dantas, Tiago J.

“…Intraflagellar transport (IFT) trains, built around IFT-A and IFT-B complexes, are carried by opposing motors to import and export ciliary cargo. While…”
Get full text

Longitudinal Natural History of Pediatric Subjects Affected with Mucopolysaccharidosis IIIB by Okur, Ilyas, Ezgu, Fatih, Giugliani, Roberto, Muschol, Nicole, Koehn, Anja, Amartino, Hernan, Harmatz, Paul, de Castro Lopez, Maria J., Couce, Maria Luz, Lin, Shuan-Pei, Batzios, Spyros, Cleary, Maureen, Solano, Martha, Peters, Heidi, Lee, Joy, Nestrasil, Igor, Shaywitz, Adam J., Maricich, Stephen M., Kuca, Bernice, Kovalchin, Joseph, Zanelli, Eric

“…OBJECTIVETo characterize the longitudinal natural history of disease progression in pediatric subjects affected with mucopolysaccharidosis (MPS) IIIB. STUDY…”
Get full text

The IFT20 homolog in Caenorhabditis elegans is required for ciliogenesis and cilia-mediated behavior by De-Castro, Ana R G, Quintas-Gonçalves, Joana, Silva-Ribeiro, Tiago, Rodrigues, Diogo R M, De-Castro, Maria J G, Abreu, Carla M, Dantas, Tiago J

“…Cilia are microtubule-based organelles that carry out a wide range of critical functions throughout the development of higher animals. Regardless of their…”
Get full text

Influence of resting energy expenditure on weight gain in adolescents taking second-generation antipsychotics by Cuerda, Cristina, Merchan-Naranjo, Jessica, Velasco, Cristina, Gutierrez, Alberto, Leiva, Marta, de Castro, Maria J, Parellada, Mara, Giráldez, Marisa, Bretón, Irene, Camblor, Miguel, García-Peris, Pilar, Dulín, Elena, Sanz, Inmaculada, Desco, Manuel, Arango, Celso

“…Summary Background & aims : Weight gain is an undesirable side effect of second-generation antipsychotics (SGAs). We performed this study to examine the…”
Get full text

Actitud respecto a la medicación antipsicótica como factor predictivo de la suspensión del tratamiento antipsicótico en el período inicial de la psicosis de inicio temprano by Fraguas, David, Llorente, Cloe, Rapado-Castro, Marta, Parellada, Mara, Moreno, Dolores, Ruiz-Sancho, Ana, Medina, Óscar, Álvarez-Segura, Mar, de Castro, María J, Arango, Celso

“…Resumen Antecedentes La suspensión de la medicación antipsicótica constituye un factor de riesgo clave para las recurrencias en la psicosis. La recurrencia…”
Get full text

Attitude toward antipsychotic medication as a predictor of antipsychotic treatment discontinuation in first-episode early-onset psychosis by Fraguas, David, Llorente, Cloe, Rapado-Castro, Marta, Parellada, Mara, Moreno, Dolores, Ruiz-Sancho, Ana, Medina, Oscar, Alvarez-Segura, Mar, de Castro, María J, Arango, Celso

“…Antipsychotic drug discontinuation is a key risk factor in psychotic relapses. Clinical relapse is related to poor outcome, especially in the earlier stages of…”
Get full text

Interim results of Transpher A, a multicentre, single-dose, phase 1/2 clinical trial of ABO-102 investigational gene therapy for Sanfilippo syndrome type A (mucopolysaccharidosis IIIA) by Flanigan, Kevin M., Smith, Nicholas J.N., Couce, Maria L., Escolar, Maria, Truxal, Kristen V., McBride, Kim L., de Castro, Maria J., Fuller, Maria, Pañeda, A., Ruiz, J., del Campo, A.B., Grachev, I.

Get full text

Attitude Toward Antipsychotic Medication as a Predictor of Antipsychotic Treatment Discontinuation in First-Episode Early-Onset Psychosis by Fraguas, David, Llorente, Cloe, Rapado-Castro, Marta, Parellada, Mara, Moreno, Dolores, Ruiz-Sancho, Ana, Medina, Óscar, Álvarez-Segura, Mar, de Castro, María J., Arango, Celso

“…Antipsychotic drug discontinuation is a key risk factor in psychosis relapses. Clinical relapse is related to poor outcome, especially in the earlier stages of…”
Get full text

ICV-administered tralesinidase alfa (BMN 250 NAGLU-IGF2) is well-tolerated and reduces heparan sulfate accumulation in the CNS of subjects with Sanfilippo syndrome type B (MPS IIIB) by Cleary, Maureen, Muschol, Nicole, Couce, Maria Luz, Harmatz, Paul, Lee, Joy, Lin, Shuan-Pei, Okur, Ilyas, Ezgu, Fatih, Peters, Heidi, Villarreal, Martha Solano, Shaywitz, Adam J., Cahan, Heather, Grover, Anita, Melton, Andrew, Smith, Lynn, Maricich, Stephen M., de Castro Lopez, Maria J.

Get full text

Study of Atlas Sensitivity to the Single Top Wt-Channel Cross Section by de Castro, Maria Inês A. J. Ochoa

“…Realizou-se o estudo da sensibilidade da experiência ATLAS, do LHC, à medida da secção eficaz do canal Wt de single top. Para tal, utilizou-se a simulação…”
Get full text