Search Results - "De Castro, G"

Ki-67 as prognostic marker in early breast cancer: a meta-analysis of published studies involving 12 155 patients by DE AZAMBUJA, E, CARDOSO, F, DE CASTRO JR, G, COLOZZA, M, MANO, M. S, DURBECQ, V, SOTIRIOU, C, LARSIMONT, D, PICCART-GEBHART, M. J, PAESMANS, M

“…The Ki-67 antigen is used to evaluate the proliferative activity of breast cancer (BC); however, Ki-67's role as a prognostic marker in BC is still undefined…”
Get full text

Use of archival versus newly collected tumor samples for assessing PD-L1 expression and overall survival: an updated analysis of KEYNOTE-010 trial by Herbst, R.S., Baas, P., Perez-Gracia, J.L., Felip, E., Kim, D.-W., Han, J.-Y., Molina, J.R., Kim, J.-H., Dubos Arvis, C., Ahn, M.-J., Majem, M., Fidler, M.J., Surmont, V., de Castro, G., Garrido, M., Shentu, Y., Emancipator, K., Samkari, A., Jensen, E.H., Lubiniecki, G.M., Garon, E.B.

“…In KEYNOTE-010, pembrolizumab versus docetaxel improved overall survival (OS) in patients with programmed death-1 protein (PD)-L1-positive advanced…”
Get full text

Associations of tissue tumor mutational burden and mutational status with clinical outcomes in KEYNOTE-042: pembrolizumab versus chemotherapy for advanced PD-L1-positive NSCLC by Mok, T.S.K., Lopes, G., Cho, B.C., Kowalski, D.M., Kasahara, K., Wu, Y.-L., de Castro, G., Turna, H.Z., Cristescu, R., Aurora-Garg, D., Loboda, A., Lunceford, J., Kobie, J., Ayers, M., Pietanza, M.C., Piperdi, B., Herbst, R.S.

“…We evaluated whether tissue tumor mutational burden (tTMB) and STK11, KEAP1, and KRAS mutations have clinical utility as biomarkers for pembrolizumab…”
Get full text

WDR60-mediated dynein-2 loading into cilia powers retrograde IFT and transition zone crossing by De-Castro, Ana R G, Rodrigues, Diogo R M, De-Castro, Maria J G, Vieira, Neide, Vieira, Cármen, Carvalho, Ana X, Gassmann, Reto, Abreu, Carla M C, Dantas, Tiago J

“…The dynein-2 motor complex drives retrograde intraflagellar transport (IFT), playing a pivotal role in the assembly and functions of cilia. However, the…”
Get full text

Renal effects of molecular targeted therapies in oncology: a review by the Cancer and the Kidney International Network (C-KIN) by Launay-Vacher, V., Aapro, M., De Castro, G., Cohen, E., Deray, G., Dooley, M., Humphreys, B., Lichtman, S., Rey, J., Scotté, F., Wildiers, H., Sprangers, B.

“…A number of cancer therapy agents are cleared by the kidney and may affect renal function, including cytotoxic chemotherapy agents, molecular targeted…”
Get full text

A DFT investigation of lithium adsorption on graphenes as a potential anode material in lithium-ion batteries by De Souza, L.A., Monteiro de Castro, G., Marques, L.F., Belchior, J.C.

“…We present a detailed study of the Li+ ion adsorption on two different hydrogenated carbon nanostructures, namely as pristine graphene (PG) and topologic…”
Get full text

Origin of the 30 THz Emission Detected During the Solar Flare on 2012 March 13 at 17:20 UT by Trottet, G., Raulin, J.-P., Mackinnon, A., Giménez de Castro, G., Simões, P. J. A., Cabezas, D., de La Luz, V., Luoni, M., Kaufmann, P.

“…Solar observations in the infrared domain can bring important clues on the response of the low solar atmosphere to primary energy released during flares. At…”
Get full text

Solvent effect on the structure and photocatalytic behavior of TiO2-RGO nanocomposites by Gonçalves, Bruno S., Silva, Lucas M. C., de Souza, Tarcizo C. C., de Castro, Vinícius G., Silva, Glaura G., Silva, Bruno C., Krambrock, Klaus, Soares, Renata B., Lins, Vanessa F. C., Houmard, Manuel, Nunes, Eduardo H. M.

“…There is no agreement regarding which solvent is more suitable to obtain sol–gel–derived titania (TiO 2 ) samples with an enhanced photocatalytic behavior…”
Get full text

Evidence-based guidelines for interpreting change scores for the European Organisation for the Research and Treatment of Cancer Quality of Life Questionnaire Core 30 by Cocks, K, King, M.T, Velikova, G, de Castro, G, Martyn St-James, M, Fayers, P.M, Brown, J.M

“…Abstract Aim To use published literature and experts’ opinion to investigate the clinical meaning and magnitude of changes in the Quality of Life (QOL) of…”
Get full text

State-of-the-art cytometry in the search of novel biomarkers in digestive cancers by G de Castro, Carolina, G Del Hierro, Alejandro, H-Vázquez, Juan, Cuesta-Sancho, Sara, Bernardo, David

“…Despite that colorectal and liver cancer are among the most prevalent tumours in the world, the identification of non-invasive biomarkers to aid on their…”
Get full text

Evaluation of the efficacy of a commercial inactivated genogroup 2b-based porcine epidemic diarrhea virus (PEDV) vaccine and experimental live genogroup 1b exposure against 2b challenge by Opriessnig, Tanja, Gerber, Priscilla F, Shen, Huigang, de Castro, Alessandra Marnie M G, Zhang, Jianqiang, Chen, Qi, Halbur, Patrick

“…Porcine epidemic diarrhea virus strains from the G1b cluster are considered less pathogenic compared to the G2b cluster. The aim of this study was to compare…”
Get full text

Evolution and conservation genetics of an insular hemiparasitic plant lineage at the limit of survival: the case of Thesium sect. Kunkeliella in the Canary Islands by Rodríguez‐Rodríguez, Priscila, Fernández de Castro, Alejandro G., Pérez de Paz, Pedro Luis, Curbelo, Leticia, Palomares, Ángel, Mesa, Ricardo, Acevedo, Aurelio, Sosa, Pedro A.

“…Premise The diversification of island flora has been widely studied. However, the role of environmental niches in insular radiation processes has been less…”
Get full text

Building train carriages for ciliary transport: (IFT-)A complex task by Gonçalves-Santos, Francisco, De-Castro, Maria J. G., De-Castro, Ana R. G., Dantas, Tiago J.

“…Cilia assembly and function require intraflagellar transport (IFT), a mechanism that uses “trains” to transport cargoes into and out of cilia. While much has…”
Get full text

Fecal microbiota transplant after hematopoietic SCT: report of a successful case by de Castro, C G, Ganc, A J, Ganc, R L, Petrolli, M S, Hamerschlack, N

Get full text

Ornithophily for the nonspecialist: Differential pollination efficiency of the Macaronesian island paleoendemic Navaea phoenicea (Malvaceae) by generalist passerines by de Castro, Alejandro G. Fernández, Moreno-Saiz, Juan Carlos, Fuertes-Aguilar, Javier

“…PREMISE OF THE STUDY: A bird pollination syndrome exists in the Canary Islands archipelago across independent plant lineages despite the absence of specialist…”
Get full text

Demographic and dendrochronological evidence reveals highly endangered status of a paleoendemic woody mallow from the Canary Islands by Fernández de Castro, Alejandro G., Rozas, Vicente, Fuertes-Aguilar, Javier, Moreno-Saiz, Juan Carlos

“…Navaea phoenicea (Malvaceae) is a flagship shrub species endemic to Tenerife Island in the Canary archipelago and is included as Endangered on the Spanish Red…”
Get full text

Impact of the COVID-19 Outbreak on Cancer Staging in Brazil by de Sousa, C.F.P.M., de Castro Junior, G., Starling, M.T.M., Restini, F.C.F., Rodrigues, A.N., de Castro Ribeiro, H.S., Arruda, G.V., Hanna, S.A., de Moraes, F.Y., Marta, G.N.

Get full text

Vernal Keratoconjunctivitis: an update focused on clinical grading system by Zicari, A M, Capata, G, Nebbioso, M, De Castro, G, Midulla, F, Leonardi, L, Loffredo, L, Spalice, A, Perri, L, Duse, M

“…Vernal keratoconjunctivitis (VKC) is a severe disease with a prevalence of < 1 case out of 10,000 in Europe, which occurs mainly in pediatric age and is…”
Get full text

What triggers phenological events in plants under seasonal environments? A study with phylogenetically related plant species in sympatry by Pereira, C C, Boaventura, M G, Cornelissen, T, Nunes, Y R F, de Castro, G C

“…In this study, we evaluated variation in vegetative and reproductive phenological events of four phylogenetically related plant species subjected to a seasonal…”
Get full text

Pollinator shifts drive petal epidermal evolution on the Macaronesian Islands bird-flowered species by Ojeda, Dario I., Valido, Alfredo, Fernández de Castro, Alejandro G., Ortega-Olivencia, Ana, Fuertes-Aguilar, Javier, Carvalho, José A., Santos-Guerra, Arnoldo

“…Pollinator shifts are considered to drive floral trait evolution, yet little is still known about the modifications of petal epidermal surface at a…”
Get full text