Search Results - "De Carvalho, Luana Martins"

Sexually dimorphic role for insular perineuronal nets in aversion-resistant alcohol consumption by Martins de Carvalho, Luana, Chen, Hu, Sutter, Mason, Lasek, Amy W

“…Compulsive alcohol drinking is a key symptom of alcohol use disorder (AUD) that is particularly resistant to treatment. An understanding of the biological…”
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TSPO polymorphism in individuals with alcohol use disorder: Association with cholesterol levels and withdrawal severity by Wiers, Corinde E., Martins De Carvalho, Luana, Hodgkinson, Colin A., Schwandt, Melanie, Kim, Sung Won, Diazgranados, Nancy, Wang, Gene‐Jack, Goldman, David, Volkow, Nora D.

“…The translocator protein (TSPO) transports cholesterol into mitochondria and is involved in steroidogenesis. The TSPO polymorphism rs6971 influences binding of…”
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Maternal separation affects expression of stress response genes and increases vulnerability to ethanol consumption by de Almeida Magalhães, Taciani, Correia, Diego, de Carvalho, Luana Martins, Damasceno, Samara, Brunialti Godard, Ana Lúcia

“…Introduction Maternal separation is an early life stress event associated with behavioral alterations and ethanol consumption. We aimed to expand the current…”
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Increased transcription of TSPO, HDAC2, and HDAC6 in the amygdala of males with alcohol use disorder by De Carvalho, Luana Martins, Wiers, Corinde E., Sun, Hui, Wang, Gene‐Jack, Volkow, Nora D.

“…Introduction Repeated exposure to high doses of alcohol triggers neuroinflammatory processes that contribute to craving and mood dysfunction in alcohol use…”
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Untargeted metabolomics reveal sex-specific and non-specific redox-modulating metabolites in kidneys following binge drinking by Rafferty, Daniel, Martins de Carvalho, Luana, Sutter, Mason, Heneghan, Katlyn, Nelson, Victoria, Leitner, Megan, Bolch, Charlotte, Lasek, Amy W, Puthanveetil, Prasanth

“…Graphical abstract Abstract Binge drinking is a growing health concern among all age groups. The ability of individuals to handle ethanol in their systems…”
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LRRK2 Gene Variants Associated With a Higher Risk for Alcohol Dependence in Multiethnic Populations by Oliveira, Pablo Rafael Silveira, de Matos, Lorena Oliveira, Araujo, Nathalia Matta, Sant Anna, Hanaísa P., da Silva e Silva, Daniel Almeida, Damasceno, Andresa K. Andrade, Martins de Carvalho, Luana, Horta, Bernardo L., Lima-Costa, Maria Fernanda, Barreto, Mauricio Lima, Wiers, Corinde E., Volkow, Nora D., Brunialti Godard, Ana Lúcia

“…Background: Genetics influence the vulnerability to alcohol use disorders, and among the implicated genes, three previous studies have provided evidences for…”
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Epigenetic mechanisms underlying stress-induced depression by Martins de Carvalho, Luana, Chen, Wei-Yang, Lasek, Amy W

“…Stressful life events are a major contributor to the development of major depressive disorder. Environmental perturbations like stress change gene expression…”
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Effect of alcohol use disorder on cellular aging by Martins de Carvalho, Luana, Wiers, Corinde E., Manza, Peter, Sun, Hui, Schwandt, Melanie, Wang, Gene-Jack, Grassi-Oliveira, Rodrigo, Godard, Ana Lúcia Brunialti, Volkow, Nora D.

“…Rationale Human telomeres consist of tandem repeats at chromosome ends which protect chromosomal DNA from degradation. Telomere shortening occurs as part of…”
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High-fat diet withdrawal modifies alcohol preference and transcription of dopaminergic and GABAergic receptors by Martins de Carvalho, Luana, Lauar Gonçalves, Juliana, Sondertoft Braga Pedersen, Agatha, Damasceno, Samara, Elias Moreira Júnior, Renato, Uceli Maioli, Tatiani, Faria, Ana Maria Caetano de, Brunialti Godard, Ana Lúcia

“…The bidirectional and positive relation between the ingestion of fat and alcohol has become the subject of extensive discussion. However, this relation is more…”
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Identifying functionally relevant candidate genes for inflexible ethanol intake in mice and humans using a guilt‐by‐association approach by Martins de Carvalho, Luana, A. S. Fonseca, Pablo, M. Paiva, Isadora, Damasceno, Samara, S. B. Pedersen, Agatha, Silva e Silva, Daniel, E. Wiers, Corinde, D. Volkow, Nora, Brunialti Godard, Ana L.

“…Gene prioritization approaches are useful tools to explore and select candidate genes in transcriptome studies. Knowing the importance of processes such as…”
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Sexually dimorphic role for insular cortex perineuronal nets in aversion-resistant alcohol consumption by Lasek, Amy W., Carvalho, Luana Martins de, Chen, Hu

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Diet-induced obesity leads to alterations in behavior and gut microbiota composition in mice by Moreira Júnior, Renato Elias, de Carvalho, Luana Martins, dos Reis, Diego Carlos, Cassali, Geovanni Dantas, Faria, Ana Maria Caetano, Maioli, Tatiani Uceli, Brunialti-Godard, Ana Lúcia

“…The high prevalence of obesity and associated metabolic disorders are one of the major public health problems worldwide. Among the main causal factors of…”
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Differential expression of alpha-synuclein in the hippocampus of SHR and SLA16 isogenic rat strains by De Barros Oliveira, Rachel, Anselmi, Mayara, Marchette, Renata Cristina Nunes, Roversi, Katiane, Fadanni, Guilherme Pasetto, De Carvalho, Luana Martins, Damasceno, Samara, Heinrich, Isabella Aparecida, Leal, Rodrigo Bainy, Cavalli, Juliana, Moreira-Júnior, Renato Elias, Godard, Ana Lúcia Brunialti, Izídio, Geison Souza

“…Two inbred strains, Lewis (LEW) and Spontaneously Hypertensive Rats (SHR), are well-known for their contrasting behavior related to anxiety/emotionality…”
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Alcohol use disorder is associated with DNA methylation-based shortening of telomere length and regulated by TESPA1: implications for aging by Jung, Jeesun, McCartney, Daniel L., Wagner, Josephin, Rosoff, Daniel B., Schwandt, Melanie, Sun, Hui, Wiers, Corinde E., de Carvalho, Luana Martins, Volkow, Nora D., Walker, Rosie M., Campbell, Archie, Porteous, David J., McIntosh, Andrew M., Marioni, Riccardo E., Horvath, Steve, Evans, Kathryn L., Lohoff, Falk W.

“…Chronic heavy alcohol consumption is associated with increased mortality and morbidity and often leads to premature aging; however, the mechanisms of…”
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Interaction between high-fat diet and ethanol intake leads to changes on the fecal microbiome by Moreira Júnior, Renato Elias, de Carvalho, Luana Martins, Pedersen, Agatha Sondertoft Braga, Damasceno, Samara, Maioli, Tatiani Uceli, de Faria, Ana Maria Caetano, Godard, Ana Lúcia Brunialti

“…It is known that high-fat diet and alcohol intake can modulate the gut microbiota and consequently affect physiological processes such as fat storage and…”
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Inhibition of Lrrk2 reduces ethanol preference in a model of acute exposure in zebrafish by Paiva, Isadora Marques, de Carvalho, Luana Martins, Di Chiaccio, Isabela Martins, Lima Assis, Isadora de, Naranjo, Elena Sánchez, Bernabé, Manuel Garcia, Ferreira, Felipe Norberto Alves, Cayuela, Maria Luisa, Murgas, Luis David Solis, Brunialti Godard, Ana Lúcia

“…Due to its multifactorial and yet to be fully understood origin, ethanol addiction is a field that still requires studies for the elucidation of novel genes…”
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