Search Results - "De Camilli, P"

JIP3 links lysosome transport to regulation of multiple components of the axonal cytoskeleton by Rafiq, N. M., Lyons, L. L., Gowrishankar, S., De Camilli, P., Ferguson, S. M.

“…Lysosome axonal transport is important for the clearance of cargoes sequestered by the endocytic and autophagic pathways. Building on observations that…”
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enzymatic cascade of Rab5 effectors regulates phosphoinositide turnover in the endocytic pathway by Shin, Hye-Won, Hayashi, Mitsuko, Christoforidis, Savvas, Lacas-Gervais, Sandra, Hoepfner, Sebastian, Wenk, Markus R, Modregger, Jan, Uttenweiler-Joseph, Sandrine, Wilm, Matthias, Nystuen, Arne, Frankel, Wayne N, Solimena, Michele, De Camilli, Pietro, Zerial, Marino

“…Generation and turnover of phosphoinositides (PIs) must be coordinated in a spatial- and temporal-restricted manner. The small GTPase Rab5 interacts with two…”
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Endophilin/SH3p4 Is Required for the Transition from Early to Late Stages in Clathrin-Mediated Synaptic Vesicle Endocytosis by Ringstad, Niels, Gad, Helge, Löw, Peter, Di Paolo, Gilbert, Brodin, Lennart, Shupliakov, Oleg, De Camilli, Pietro

“…Endophilin/SH3p4 is a protein highly enriched in nerve terminals that binds the GTPase dynamin and the polyphosphoinositide phosphatase synaptojanin, two…”
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Synapsin I (Protein I), a Nerve Terminal-Specific Phosphoprotein. I. Its General Distribution in Synapses of The Central and Peripheral Nervous System Demonstrated by Immunofluorescence in Frozen and Plastic Sections by De Camilli, P., Cameron, R., Greengard, P.

“…Synapsin I (formerly referred to as protein I) is the collective name for two almost identical phosphoproteins, synapsin Ia and synapsin Ib (protein Ia and…”
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The Synaptic Vesicle Cycle: A Single Vesicle Budding Step Involving Clathrin and Dynamin by Takei, Kohji, Mundigl, Olaf, Daniell, Laurie, De Camilli, Pietro

“…Strong evidence implicates clathrin-coated vesicles and endosome-like vacuoles in the reformation of synaptic vesicles after exocytosis, and it is generally…”
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A Role of Amphiphysin in Synaptic Vesicle Endocytosis Suggested by its Binding to Dynamin in Nerve Terminals by David, Carol, McPherson, Peter S., Mundigl, Olaf, De Camilli, Pietro

“…Amphiphysin, a major autoantigen in paraneoplastic Stiff-Man syndrome, is an SH3 domain-containing neuronal protein, concentrated in nerve terminals. Here, we…”
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Inositol 1,4,5-trisphosphate receptor causes formation of ER cisternal stacks in transfected fibroblasts and in cerebellar Purkinje cells by Takei, K, Mignery, G A, Mugnaini, E, Südhof, T C, De Camilli, P

“…The inositol 1,4,5-trisphosphate receptor (IP3R) is expressed at very high levels in cerebellar Purkinje cells. Within these neurons, it has a widespread…”
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Markedly elevated GAD antibodies in SPS: Effects of age and illness duration by MURINSON, B. B, BUTLER, M, MARFURT, K, GLEASON, S, DE CAMILLI, P, SOLIMENA, M

“…Five hundred seventy-six patients with suspected stiff-person syndrome (SPS) underwent immunocytochemistry (ICC). Of these, 286 underwent radioimmunoassay…”
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Amphiphysin is a Component of Clathrin Coats Formed During Synaptic Vesicle Recycling at the Lamprey Giant Synapse by Evergren, Emma, Marcucci, Melissa, Tomilin, Nikolay, Löw, Peter, Slepnev, Vladimir, Andersson, Fredrik, Gad, Helge, Brodin, Lennart, De Camilli, Pietro, Shupliakov, Oleg

“…Amphiphysin is a protein enriched at mammalian synapses thought to function as a clathrin accessory factor in synaptic vesicle endocytosis. Here we examine the…”
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Secretory function of the vestibular nerve calyx suggested by presence of vesicles, synapsin I, and synaptophysin by Scarfone, E, Dememes, D, Jahn, R, De Camilli, P, Sans, A

“…Type I sensory hair cells of the vestibular epithelium are nearly completely ensheathed by an afferent nerve ending, the vestibular nerve calyx. We have…”
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Synaptic vesicle endocytosis by Saheki, Yasunori, De Camilli, Pietro

“…Neurons can sustain high rates of synaptic transmission without exhausting their supply of synaptic vesicles. This property relies on a highly efficient local…”
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Differential Effect of α -latrotoxin on Exocytosis from Small Synaptic Vesicles and from Large Dense-Core Vesicles Containing Calcitonin Gene-Related Peptide at the Frog Neuromuscular Junction by Matteoli, M., Haimann, C., Torri-Tarelli, F., Polak, J. M., Ceccarelli, B., De Camilli, P.

“…The regulatory peptide called calcitonin gene-related peptide (CGRP) was detected by immunofluorescence in frog motor neurons and motor nerve terminals. In…”
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Anti-amphiphysin I antibodies in patients with paraneoplastic neurological disorders associated with small cell lung carcinoma by Saiz, A, Dalmau, J, Butler, M Husta, Chen, Q, Delattre, J Y, De Camilli, P, Graus, F

“…Patients with stiff man syndrome and breast cancer develop anti-amphiphysin I antibodies that primarily recognise the C terminus of the protein…”
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Association of GAD-65, but not of GAD-67, with the Golgi Complex of Transfected Chinese Hamster Ovary Cells Mediated by the N-Terminal Region by Solimena, M., Aggujaro, D., Muntzel, C., Dirkx, R., Butler, M., De Camilli, P., Hayday, A.

“…Glutamic acid decarboxylase (GAD) is the enzyme responsible for synthesis of the neurotransmitter γ-aminobutyric acid in neurons and pancreatic β cells. It is…”
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The distribution of synapsin I and synaptophysin in hippocampal neurons developing in culture by Fletcher, TL, Cameron, P, De Camilli, P, Banker, G

“…As a first step toward elucidating mechanisms involved in the sorting of synaptic vesicle proteins in neurons, we have used immunofluorescence microscopy to…”
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Synaptophysin is targeted to similar microvesicles in CHO and PC12 cells by Johnston, P.A., Cameron, P.L., Stukenbrok, H., Jahn, R., De Camilli, P., Südhof, T.C.

“…Synaptophysin, an integral membrane protein of small synaptic vesicles, was expressed by transfection in fibroblastic CHO‐K1 cells. The properties and…”
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GABA and pancreatic beta‐cells: colocalization of glutamic acid decarboxylase (GAD) and GABA with synaptic‐like microvesicles suggests their role in GABA storage and secretion by Reetz, A., Solimena, M., Matteoli, M., Folli, F., Takei, K., De Camilli, P.

“…GABA, a major inhibitory neurotransmitter of the brain, is also present at high concentration in pancreatic islets. Current evidence suggests that within…”
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The synaptic vesicle proteins synapsin I and synaptophysin (protein P38) are concentrated both in efferent and afferent nerve endings of the skeletal muscle by De Camilli, P, Vitadello, M, Canevini, MP, Zanoni, R, Jahn, R, Gorio, A

“…Synapsin I and synaptophysin (protein p38) are 2 major protein components of the membranes of small synaptic vesicles of virtually all presynaptic nerve…”
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Exo-Endocytotic Recycling of Synaptic Vesicles in Developing Processes of Cultured Hippocampal Neurons by Matteoli, Michela, Takei, Kohji, Perin, Mark S., Südhof, Thomas C., De Camilli, Pietro

“…In mature neurons synaptic vesicles (SVs) undergo cycles of exo-endocytosis at synapses. It is currently unknown whether SV exocytosis and recycling occurs…”
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Immunohistochemical localization of secretogranin II in the rat cerebellum by Cozzi, M G, Rosa, P, Greco, A, Hille, A, Huttner, W B, Zanini, A, De Camilli, P

“…Secretogranin II (chromogranin C) is a peptide related to chromogranin A and secretogranin I (chromogranin B) which is secreted by a regulated pathway from…”
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