Search Results - "De Bundel, D."

Dopamine D2 receptors gate generalization of conditioned threat responses through mTORC1 signaling in the extended amygdala by De Bundel, D, Zussy, C, Espallergues, J, Gerfen, C R, Girault, J-A, Valjent, E

“…Overgeneralization of conditioned threat responses is a robust clinical marker of anxiety disorders. In overgeneralization, responses that are appropriate to…”
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Dysfunctional astrocytic regulation of glutamate transmission in a rat model of depression by Gómez-Galán, M, De Bundel, D, Van Eeckhaut, A, Smolders, I, Lindskog, M

“…Depression is usually associated with alterations in the monoaminergic system. However, new evidences suggest the involvement of the glutamatergic system in…”
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Optical activation of endogenous metabotropic glutamate receptor 4 (mGlu4) in the amygdala dynamically regulates symptoms associated with persistent inflammatory pain by Zussy, C, Gómez-Santacana, X, Rovira, X, De Bundel, D, Ferrazzo, S, Bosch, D, Asede, D, Malhaire, F, Acher, F, Giraldo, J, Valjent, E, Ehrlich, I, Ferraguti, F, Pin, J-P, Llebaria, A, Goudet, C

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Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4 by Zussy, C, Gómez-Santacana, X, Rovira, X, De Bundel, D, Ferrazzo, S, Bosch, D, Asede, D, Malhaire, F, Acher, F, Giraldo, J, Valjent, E, Ehrlich, I, Ferraguti, F, Pin, J-P, Llebaria, A, Goudet, C

“…Contrary to acute pain, chronic pain does not serve as a warning signal and must be considered as a disease per se . This pathology presents a sensory and…”
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Effects of disrupted ghrelin receptor function on fear processing, anxiety and saccharin preference in mice by Pierre, A., Regin, Y., Van Schuerbeek, A., Fritz, E.M., Muylle, K., Beckers, T., Smolders, I.J., Singewald, N., De Bundel, D.

“…•Exposure to a high-fat diet reduces ghrelin receptor function.•Exposure to a high-fat diet does not alter fear or anxiety-like behaviour but lowers saccharin…”
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Antidepressant Drugs Specifically Inhibiting Noradrenaline Reuptake Enhance Recognition Memory in Rats by Feltmann, Kristin, Konradsson-Geuken, Åsa, De Bundel, Dimitri, Lindskog, Maria, Schilström, Björn

“…Patients suffering from major depression often experience memory deficits even after the remission of mood symptoms, and many antidepressant drugs do not…”
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Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model by Demuyser, Thomas, Deneyer, Lauren, Bentea, Eduard, Albertini, Giulia, Femenia, Teresa, Walrave, Laura, Sato, Hideyo, Danbolt, Niels C., De Bundel, Dimitri, Michotte, Alex, Lindskog, Maria, Massie, Ann, Smolders, Ilse

“…Objectives: The cystine/glutamate antiporter (system xc-) is believed to contribute to nonvesicular glutamate release from glial cells in various brain areas…”
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Spatial distribution of D1R- and D2R-expressing medium-sized spiny neurons differs along the rostro-caudal axis of the mouse dorsal striatum by Gangarossa, Giuseppe, Espallergues, Julie, Mailly, Philippe, De Bundel, Dimitri, de Kerchove d'Exaerde, Alban, Hervé, Denis, Girault, Jean-Antoine, Valjent, Emmanuel, Krieger, Patrik

“…The striatum projection neurons are striatonigral and striatopallidal medium-sized spiny neurons (MSNs) that preferentially express D1 (D1R) and D2 (D2R)…”
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Trans-Modulation of the Somatostatin Type 2A Receptor Trafficking by Insulin-Regulated Aminopeptidase Decreases Limbic Seizures by De Bundel, Dimitri, Fafouri, Assia, Csaba, Zsolt, Loyens, Ellen, Lebon, Sophie, El Ghouzzi, Vincent, Peineau, Stéphane, Vodjdani, Guilan, Kiagiadaki, Foteini, Aourz, Najat, Coppens, Jessica, Walrave, Laura, Portelli, Jeanelle, Vanderheyden, Patrick, Chai, Siew Yeen, Thermos, Kyriaki, Bernard, Véronique, Collingridge, Graham, Auvin, Stéphane, Gressens, Pierre, Smolders, Ilse, Dournaud, Pascal

“…Within the hippocampus, the major somatostatin (SRIF) receptor subtype, the sst2A receptor, is localized at postsynaptic sites of the principal neurons where…”
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P.2.018 Antidepressants specifically inhibiting noradrenaline reuptake enhance recognition memory in rats by Feltmann, K, Konradsson-Geuken, A, De Bundel, D, Schilström, B, Lindskog, M

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Deletion of insulin-regulated aminopeptidase in mice decreases susceptibility to pentylenetetrazol-induced generalized seizures by Loyens, E, Schallier, A, Chai, S.Y, De Bundel, D, Vanderheyden, P, Michotte, Y, Smolders, I

“…Abstract The peptide angiotensin IV (Ang IV) influences seizure susceptibility in rat and mouse models. Indeed, Ang IV has been shown to protect rats from…”
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Fear modulation by transcranial direct current stimulation by Van Schuerbeek, A., Pierre, A., Vanderhasselt, M., Pedron, S., Van Waes, V., De Bundel, D.

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Accelerated high-frequency repetitive transcranial magnetic stimulation positively influences the behavior, monoaminergic system, and cerebral perfusion in anxious aggressive dogs: A case study by Dockx, R., Baeken, C., De Bundel, D., Saunders, J.H., Van Eeckhaut, A., Peremans, K.

“…Accelerated high-frequency repetitive transcranial magnetic stimulation (aHF-rTMS) was proven to produce fast clinical effects in humans suffering from…”
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Acute accelerated high frequency TMS augments homovanillic acid and 3,4-dihydroxyphenylacetic acid in the cerebrospinal fluid of healthy dogs by Dockx, R., Peremans, K., De Bundel, D., Van Eeckhaut, A., Vlerick, L., Polis, I., Goethals, I., Dobbeleir, A., Saunders, J., Baeken, C.

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Hippocampal and prefrontal dopamine D1/5 receptor involvement in the memory-enhancing effect of reboxetine by De Bundel, Dimitri, Femenía, Teresa, DuPont, Caitlin M., Konradsson-Geuken, Åsa, Feltmann, Kritin, Schilström, Björn, Lindskog, Maria

“…Dopamine modulates cognitive functions through regulation of synaptic transmission and plasticity in the hippocampus and prefrontal cortex (PFC). Thus,…”
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Angiotensin IV and LVV-haemorphin 7 enhance spatial working memory in rats: Effects on hippocampal glucose levels and blood flow by De Bundel, Dimitri, Smolders, Ilse, Yang, Rui, Albiston, Anthony L., Michotte, Yvette, Chai, Siew Yeen

“…The IRAP ligands Angiotensin IV (Ang IV) and LVV-haemorphin 7 (LVV-H7) enhance performance in a range of memory paradigms in normal rats and ameliorate memory…”
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Hippocampal and prefrontal dopamine D 1/5 receptor involvement in the memory-enhancing effect of reboxetine by De, Bundel D, Femenia, T, DuPont, CM, Konradsson-Geuken, A, Feltmann, K, Schilstrm, B, Lindskog, M

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Hippocampal sst1 receptors are autoreceptors and do not affect seizures in rats by De Bundel, Dimitri, Aourz, Najat, Kiagiadaki, Foteini, Clinckers, Ralph, Hoyer, Daniel, Kastellakis, Andreas, Michotte, Yvette, Thermos, Kyriaki, Smolders, Ilse

“…Somatostatin-14 (SRIF-14) exerts anticonvulsive effects in several rat seizure models, generally attributed to sst2 receptor activation. Whereas sst1…”
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Involvement of insulin-regulated aminopeptidase and/or aminopeptidase N in the angiotensin IV-induced effect on dopamine release in the striatum of the rat by Stragier, Bart, Demaegdt, Heidi, De Bundel, Dimitri, Smolders, Ilse, Sarre, Sophie, Vauquelin, Georges, Ebinger, Guy, Michotte, Yvette, Vanderheyden, Patrick

“…Abstract Locally administered angiotensin IV causes a dose-dependent increase of the dopamine levels in the striatum of the rat. The aminopeptidases…”
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Loss of system x(c)- does not induce oxidative stress but decreases extracellular glutamate in hippocampus and influences spatial working memory and limbic seizure susceptibility by De Bundel, Dimitri, Schallier, Anneleen, Loyens, Ellen, Fernando, Ruani, Miyashita, Hirohisa, Van Liefferinge, Joeri, Vermoesen, Katia, Bannai, Shiro, Sato, Hideyo, Michotte, Yvette, Smolders, Ilse, Massie, Ann

“…System x(c)- exchanges intracellular glutamate for extracellular cystine, giving it a potential role in intracellular glutathione synthesis and nonvesicular…”
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