Search Results - "De Both, Matthew D"
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Family history of Alzheimer's disease alters cognition and is modified by medical and genetic factors
Published in eLife (18-06-2019)“…In humans, a first-degree family history of dementia (FH) is a well-documented risk factor for Alzheimer's disease (AD); however, the influence of FH on…”
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Transcriptional profiling of multiple system atrophy cerebellar tissue highlights differences between the parkinsonian and cerebellar sub-types of the disease
Published in Acta neuropathologica communications (03-06-2020)“…Multiple system atrophy (MSA) is a rare adult-onset neurodegenerative disease of unknown cause, with no effective therapeutic options, and no cure. Limited…”
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Associations of MAP2K3 Gene Variants With Superior Memory in SuperAgers
Published in Frontiers in aging neuroscience (29-05-2018)“…: SuperAgers are adults age 80+ with episodic memory performance that is as good as that of average middle-aged adults. Understanding the biological…”
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Transient ACE (Angiotensin-Converting Enzyme) Inhibition Suppresses Future Fibrogenic Capacity and Heterogeneity of Cardiac Fibroblast Subpopulations
Published in Hypertension (Dallas, Tex. 1979) (03-03-2021)“…Transient ACE (angiotensin-converting enzyme) inhibition in spontaneously hypertensive rats is known to protect against future injury-induced cardiac…”
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Comparative Analysis of 16S rRNA Gene and Metagenome Sequencing in Pediatric Gut Microbiomes
Published in Frontiers in microbiology (15-07-2021)“…The colonization of the human gut microbiome begins at birth, and over time, these microbial communities become increasingly complex. Most of what we currently…”
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Neuroimaging and verbal memory assessment in healthy aging adults using a portable low-field MRI scanner and a web-based platform: results from a proof-of-concept population-based cross-section study
Published in Brain Structure and Function (01-03-2023)“…Consumer wearables and health monitors, internet-based health and cognitive assessments, and at-home biosample (e.g., saliva and capillary blood) collection…”
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Association of AEBP1 and NRN1 RNA expression with Alzheimer’s disease and neurofibrillary tangle density in middle temporal gyrus
Published in Brain research (15-09-2019)“…•AEBP1 and NRN1 are differentially expressed in AD brain.•AEBP1 and NRN1 are correlated with Braak stage and tangles density.•Non-protein coding RNAs perturb…”
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Association of Common Genetic Variants in the CPSF7 and SDHAF2 Genes with Canine Idiopathic Pulmonary Fibrosis in the West Highland White Terrier
Published in Genes (30-05-2020)“…Canine idiopathic pulmonary fibrosis (CIPF) is a chronic fibrotic lung disease that is observed at a higher frequency in the West Highland White Terrier dog…”
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ESHRD: deconvolution of brain homogenate RNA expression data to identify cell-type-specific alterations in Alzheimer's disease
Published in Aging (Albany, NY.) (02-03-2020)“…We describe herein a bioinformatics approach that leverages gene expression data from brain homogenates to derive cell-type specific differential expression…”
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Transient ACE (Angiotensin-Converting Enzyme) Inhibition Suppresses Future Fibrogenic Capacity and Heterogeneity of Cardiac Fibroblast Subpopulations
Published in Hypertension (Dallas, Tex. 1979) (25-01-2021)“…Transient ACE (angiotensin-converting enzyme) inhibition in spontaneously hypertensive rats is known to protect against future injury-induced cardiac…”
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Parent-reported child appetite moderates relationships between child genetic obesity risk and parental feeding practices
Published in Frontiers in nutrition (Lausanne) (31-05-2023)“…Food parenting practices are associated with child weight. Such associations may reflect the effects of parents' practices on children's food intake and…”
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