Search Results - "De Boer, H. A."

Higher order Arabidopsis 14-3-3 mutants show 14-3-3 involvement in primary root growth both under control and abiotic stress conditions by van Kleeff, P. J. M, Jaspert, N, Li, K. W, Rauch, S, Oecking, C, de Boer, A. H

“…Arabidopsis 14-3-3 proteins are a family of conserved proteins that interact with numerous partner proteins in a phospho-specific manner, and can affect the…”
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A critical view on lactose-based drug formulation and device studies for dry powder inhalation: Which are relevant and what interactions to expect? by de Boer, A.H., Chan, H.K., Price, R.

“…Many years of research have not led to a profound knowledge of the mechanisms involved in the formulation and dispersion of carrier based mixtures for…”
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A comparison between spray drying and spray freeze drying to produce an influenza subunit vaccine powder for inhalation by Saluja, V., Amorij, J-P., Kapteyn, J.C., de Boer, A.H., Frijlink, H.W., Hinrichs, W.L.J.

“…The aim of this study was to investigate two different processes to produce a stable influenza subunit vaccine powder for pulmonary immunization i.e. spray…”
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Dry powder inhalers for pulmonary drug delivery by Frijlink, H W, De Boer, A H

“…The pulmonary route is an interesting route for drug administration, both for effective local therapy (asthma, chronic obstructive pulmonary disease or cystic…”
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Logistics of water and salt transport through the plant: structure and functioning of the xylem by DE BOER, A. H., VOLKOV, V.

“…ABSTRACT The xylem is a long‐distance transport system that is unique to higher plants. It evolved into a very sophisticated plumbing system ensuring…”
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V-ATPase from etiolated barley (Hordeum vulgare L.) shoots is activated by blue light and interacts with 14-3-3 proteins by Klychnikov, OI, Li, KW, Lill, H, de Boer, AH

“…The vacuolar H⁺-ATPase (V-ATPase) is a key enzyme that controls the electrochemical proton potential across endomembranes. Although evidence suggests that…”
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Lactoferrin is a lipid A-binding protein by APPELMELK, B. J, YUN-QING AN, GEERTS, M, THIJS, B. G, DE BOER, H. A, MACLAREN, D. M, DE GRAAFF, J, NUIJENS, J. H

“…Classifications Services IAI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Characterization of inhalation aerosols: a critical evaluation of cascade impactor analysis and laser diffraction technique by de Boer, A.H, Gjaltema, D, Hagedoorn, P, Frijlink, H.W

“…Cascade impactor analysis is the standard technique for in vitro characterization of aerosol clouds generated by medical aerosol generators. One important…”
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Dry powder inhalation of antibiotics in cystic fibrosis therapy: part 2: Inhalation of a novel colistin dry powder formulation: a feasibility study in healthy volunteers and patients by Le Brun, P.P.H, de Boer, A.H, Mannes, G.P.M, de Fraı̂ture, D.M.I, Brimicombe, R.W, Touw, D.J, Vinks, A.A, Frijlink, H.W, Heijerman, H.G.M

“…The aim of the present study was to perform a proof of principle study with a new colistin dry powder inhalation system in six healthy volunteers and five…”
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Can Patients with Parkinson's Disease Use Dry Powder Inhalers during Off Periods? by Luinstra, M, Rutgers, A W F, Dijkstra, H, Grasmeijer, F, Hagedoorn, P, Vogelzang, J M J, Frijlink, H W, de Boer, A H

“…Because of its rapid onset of action, pulmonary administration of levodopa is an interesting alternative to oral administration for the rescue treatment of…”
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Properties of two outward-rectifying channels in root xylem parenchyma cells suggest a role in K+ homeostasis and long-distance signaling by Wegner, L.H, Boer, A.H. de

“…Xylem parenchyma cells (XPCs) control the composition of the transpiration stream in plants and are thought to play a role in long-distance signaling as well…”
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Plant 14-3-3 proteins assist ion channels and pumps by de Boer, A H

“…Turgor pressure is a cellular parameter, important for a range of physiological processes in plants, like cell elongation, gas exchange and…”
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Air classifier technology (ACT) in dry powder inhalation. Part 4. Performance of air classifier technology in the Novolizer® multi-dose dry powder inhaler by DE BOER, A. H, HAGEDOORN, P, GJALTEMA, D, GOEDE, J, FRIJLINK, H. W

“…In this study, the in vitro fine particle deposition from a multi dose dry powder inhaler (Novolizer) with air classifier technology has been investigated. It…”
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Particle size matters: diagnostics and treatment of small airways involvement in asthma by COHEN, J, POSTMA, D. S, DOUMA, W. R, VONK, J. M, DE BOER, A. H, TEN HACKEN, N. H. T

“…Small airways are an important site of inflammation and obstruction in asthma, which contributes to the severity of airway hyperresponsiveness (AHR) that is…”
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Dry powder inhalation of colistin sulphomethate in healthy volunteers: A pilot study by Westerman, E.M., de Boer, A.H., Le Brun, P.P.H., Touw, D.J., Frijlink, H.W., Heijerman, H.G.M.

“…Pulmonary administration of the antimicrobial drugs colistin sulphomethate and tobramycin has been shown to be effective in slowing down pulmonary…”
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Dry powder inhalation of antibiotics in cystic fibrosis therapy, part 1: development of a powder formulation with colistin sulfate for a special test inhaler with an air classifier as de-agglomeration principle by de Boer, A.H, Le Brun, P.P.H, van der Woude, H.G, Hagedoorn, P, Heijerman, H.G.M, Frijlink, H.W

“…The aim of this study was to investigate the pulmonary administration of antibiotics as dry powder to patients with cystic fibrosis (CF), as an alternative for…”
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The effect of carrier surface and bulk properties on drug particle detachment from crystalline lactose carrier particles during inhalation, as function of carrier payload and mixing time by Dickhoff, B.H.J., de Boer, A.H., Lambregts, D., Frijlink, H.W.

“…The effect of carrier payload and mixing time on the redispersion of drug particles from adhesive mixtures during inhalation for two different drugs…”
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Technological and practical challenges of dry powder inhalers and formulations by Hoppentocht, M., Hagedoorn, P., Frijlink, H.W., de Boer, A.H.

“…In the 50years following the introduction of the first dry powder inhaler to the market, several developments have occurred. Multiple-unit dose and multi-dose…”
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Dry powder inhalation: past, present and future by de Boer, A H, Hagedoorn, P, Hoppentocht, M, Buttini, F, Grasmeijer, F, Frijlink, H W

“…Early dry powder inhalers (DPIs) were designed for low drug doses in asthma and COPD therapy. Nearly all concepts contained carrier-based formulations and…”
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A critical evaluation of the relevant parameters for drug redispersion from adhesive mixtures during inhalation by de Boer, A.H., Dickhoff, B.H.J., Hagedoorn, P., Gjaltema, D., Goede, J., Lambregts, D., Frijlink, H.W.

“…In this paper, the parameters that are relevant to the drug redispersion from adhesive mixtures during inhalation are discussed and evaluated. The results…”
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