Search Results - "De Benedittis, Caterina"

Ponatinib as a Valid Alternative Strategy in Patients with Blast Crisis-Chronic Myeloid Leukemia Not Eligible for Allogeneic Stem Cells Transplantation and/or Conventional Chemotherapy: Report of a Case by Iurlo, Alessandra, De Benedittis, C., Zappa, Manuela, Ferla, Valeria, Cattaneo, Daniele, Bucelli, Cristina, Soverini, S.

“…Currently, imatinib and dasatinib are the only tyrosine-kinase inhibitors approved in the US and Europe for the treatment of blast crisis of chronic myeloid…”
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Radiomics of cholangiocarcinoma on pretreatment CT can identify patients who would best respond to radioembolisation by Mosconi, Cristina, Cucchetti, Alessandro, Bruno, Antonio, Cappelli, Alberta, Bargellini, Irene, De Benedittis, Caterina, Lorenzoni, Giulia, Gramenzi, Annagiulia, Tarantino, Francesco Paolo, Parini, Lorenza, Pettinato, Vincenzina, Modestino, Francesco, Peta, Giuliano, Cioni, Roberto, Golfieri, Rita

“…Objectives Results after trans-arterial radioembolisation (TARE) for intrahepatic cholangiocarcinoma (iCC) depend on the architecture of the tumour. This…”
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Unraveling the complexity of tyrosine kinase inhibitor–resistant populations by ultra-deep sequencing of the BCR-ABL kinase domain by Soverini, Simona, De Benedittis, Caterina, Machova Polakova, K., Brouckova, Adela, Horner, David, Iacono, Michele, Castagnetti, Fausto, Gugliotta, Gabriele, Palandri, Francesca, Papayannidis, Cristina, Iacobucci, Ilaria, Venturi, Claudia, Bochicchio, Maria Teresa, Klamova, Hana, Cattina, Federica, Russo, Domenico, Bresciani, Paola, Binotto, Gianni, Giannini, Barbara, Kohlmann, Alexander, Haferlach, Torsten, Roller, Andreas, Rosti, Gianantonio, Cavo, Michele, Baccarani, Michele, Martinelli, Giovanni

“…In chronic myeloid leukemia and Philadelphia chromosome–positive acute lymphoblastic leukemia, tyrosine kinase inhibitor (TKI) therapy may select for…”
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Mutations in the BCR-ABL1 Kinase Domain and Elsewhere in Chronic Myeloid Leukemia by Soverini, Simona, de Benedittis, Caterina, Mancini, Manuela, Martinelli, Giovanni

“…Abstract Chronic myeloid leukemia (CML) has been the first human malignancy to be associated, more than 50 years ago, with a consistent chromosomal…”
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BCR-ABL1 compound mutants: prevalence, spectrum and correlation with tyrosine kinase inhibitor resistance in a consecutive series of Philadelphia chromosome-positive leukemia patients analyzed by NGS by Soverini, Simona, Martelli, Margherita, Bavaro, Luana, De Benedittis, Caterina, Sica, Simona, Sorà, Federica, Iurlo, Alessandra, Bonifacio, Massimiliano, Pregno, Patrizia, Galimberti, Sara, Lunghi, Francesca, Albano, Francesco, D’Adda, Mariella, Crugnola, Monica, Capodanno, Isabella, Castagnetti, Fausto, Gugliotta, Gabriele, Papayannidis, Cristina, Rosti, Gianantonio, Percesepe, Antonio, Mignone, Flavio, Baccarani, Michele, Martinelli, Giovanni, Cavo, Michele

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Survival and Tolerability of Transarterial Chemoembolization in Greater Versus less than 70 Years of Age Patients with Unresectable Hepatocellular Carcinoma: A Propensity Score Analysis by Mosconi, Cristina, Gramenzi, Annagiulia, Biselli, Maurizio, Cappelli, Alberta, Bruno, Antonio, De Benedittis, Caterina, Cucchetti, Alessandro, Modestino, Francesco, Peta, Giuliano, Bianchi, Giampaolo, Trevisani, Franco, Golfieri, Rita

“…Background The number of elderly patients diagnosed with hepatocellular carcinoma (HCC) is progressively increasing. The aim of this study was to determine the…”
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Next-generation sequencing for sensitive detection of BCR-ABL1 mutations relevant to tyrosine kinase inhibitor choice in imatinib-resistant patients by Soverini, Simona, De Benedittis, Caterina, Polakova, Katerina Machova, Linhartova, Jana, Castagnetti, Fausto, Gugliotta, Gabriele, Papayannidis, Cristina, Mancini, Manuela, Klamova, Hana, Salvucci, Marzia, Crugnola, Monica, Iurlo, Alessandra, Albano, Francesco, Russo, Domenico, Rosti, Gianantonio, Cavo, Michele, Baccarani, Michele, Martinelli, Giovanni

“…In chronic myeloid leukemia (CML) and Philadelphia-positive (Ph+) acute lymphoblastic leukemia (ALL) patients who fail imatinib treatment, BCR-ABL1 mutation…”
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FOXM1 Transcription Factor: A New Component of Chronic Myeloid Leukemia Stem Cell Proliferation Advantage by Mancini, Manuela, Castagnetti, Fausto, Soverini, Simona, Leo, Elisa, De Benedittis, Caterina, Gugliotta, Gabriele, Rosti, Gianantonio, Bavaro, Luana, De Santis, Sara, Monaldi, Cecilia, Martelli, Margherita, Santucci, Maria Alessandra, Cavo, Michele, Martinelli, Giovanni

“…ABSTRACT FOXM1 transcription factor is a central component of tumor initiation, growth, and progression due to its multiple effects on cell cycle, DNA repair,…”
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The Heterogeneity of Skewness in T2W-Based Radiomics Predicts the Response to Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer by Coppola, Francesca, Mottola, Margherita, Lo Monaco, Silvia, Cattabriga, Arrigo, Cocozza, Maria Adriana, Yuan, Jia Cheng, De Benedittis, Caterina, Cuicchi, Dajana, Guido, Alessandra, Rojas Llimpe, Fabiola Lorena, D'Errico, Antonietta, Ardizzoni, Andrea, Poggioli, Gilberto, Strigari, Lidia, Morganti, Alessio Giuseppe, Bazzoli, Franco, Ricciardiello, Luigi, Golfieri, Rita, Bevilacqua, Alessandro

“…Our study aimed to investigate whether radiomics on MRI sequences can differentiate responder (R) and non-responder (NR) patients based on the tumour…”
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14-3-3 Binding and Sumoylation Concur to the Down-Modulation of β-catenin Antagonist chibby 1 in Chronic Myeloid Leukemia by Mancini, Manuela, Leo, Elisa, Takemaru, Ken-Ichi, Campi, Virginia, Castagnetti, Fausto, Soverini, Simona, De Benedittis, Caterina, Rosti, Gianantonio, Cavo, Michele, Santucci, Maria Alessandra, Martinelli, Giovanni

“…The down-modulation of the β-catenin antagonist Chibby 1 (CBY1) associated with the BCR-ABL1 fusion gene of chronic myeloid leukemia (CML) contributes to the…”
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Calreticulin: Challenges Posed by the Intrinsically Disordered Nature of Calreticulin to the Study of Its Function by Varricchio, Lilian, Falchi, Mario, Dall'Ora, Massimiliano, De Benedittis, Caterina, Ruggeri, Alessandra, Uversky, Vladimir N, Migliaccio, Anna Rita

“…Calreticulin is a Ca -binding chaperone protein, which resides mainly in the endoplasmic reticulum but also found in other cellular compartments including the…”
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Classification Performance for COVID Patient Prognosis from Automatic AI Segmentation—A Single-Center Study by Biondi, Riccardo, Curti, Nico, Coppola, Francesca, Giampieri, Enrico, Vara, Giulio, Bartoletti, Michele, Cattabriga, Arrigo, Cocozza, Maria Adriana, Ciccarese, Federica, De Benedittis, Caterina, Cercenelli, Laura, Bortolani, Barbara, Marcelli, Emanuela, Pierotti, Luisa, Strigari, Lidia, Viale, Pierluigi, Golfieri, Rita, Castellani, Gastone

“…Background: COVID assessment can be performed using the recently developed individual risk score (prediction of severe respiratory failure in hospitalized…”
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The clonal evolution of two distinct T315I-positive BCR-ABL1 subclones in a Philadelphia-positive acute lymphoblastic leukemia failing multiple lines of therapy: a case report by De Benedittis, Caterina, Papayannidis, Cristina, Venturi, Claudia, Abbenante, Maria Chiara, Paolini, Stefania, Parisi, Sarah, Sartor, Chiara, Cavo, Michele, Martinelli, Giovanni, Soverini, Simona

“…The treatment of Philadelphia chromosome-positive Acute Lymphoblastic Leukemia (Ph+ ALL) patients who harbor the T315I BCR-ABL1 mutation or who have two or…”
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Best Practices in Chronic Myeloid Leukemia Monitoring and Management by Soverini, Simona, De Benedittis, Caterina, Mancini, Manuela, Martinelli, Giovanni

“…Optimal use of current therapeutic opportunities for chronic myeloid leukemia patients requires integration of clinical and laboratory monitoring. Assessment…”
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Present and future of molecular monitoring in chronic myeloid leukaemia by Soverini, Simona, De Benedittis, Caterina, Mancini, Manuela, Martinelli, Giovanni

“…Summary Currently, physicians treating chronic myeloid leukaemia (CML) patients can rely on a wide spectrum of therapeutic options: the best use of such…”
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Prospective assessment of NGS-detectable mutations in CML patients with nonoptimal response: the NEXT-in-CML study by Soverini, Simona, Bavaro, Luana, De Benedittis, Caterina, Martelli, Margherita, Iurlo, Alessandra, Orofino, Nicola, Sica, Simona, Sorà, Federica, Lunghi, Francesca, Ciceri, Fabio, Galimberti, Sara, Baratè, Claudia, Bonifacio, Massimiliano, Scaffidi, Luigi, Castagnetti, Fausto, Gugliotta, Gabriele, Albano, Francesco, Russo Rossi, Antonella Vita, Stagno, Fabio, di Raimondo, Francesco, D'Adda, Mariella, di Bona, Eros, Abruzzese, Elisabetta, Binotto, Gianni, Sancetta, Rosaria, Salvucci, Marzia, Capodanno, Isabella, Girasoli, Mariella, Coluzzi, Sabrina, Attolico, Immacolata, Musolino, Caterina, Calistri, Elisabetta, Annunziata, Mario, Bocchia, Monica, Stella, Stefania, Serra, Anna, Errichiello, Santa, Saglio, Giuseppe, Pane, Fabrizio, Vigneri, Paolo, Mignone, Flavio, Laginestra, Maria Antonella, Pileri, Stefano Aldo, Percesepe, Antonio, Tenti, Elena, Rosti, Gianantonio, Baccarani, Michele, Cavo, Michele, Martinelli, Giovanni

“…In chronic myeloid leukemia (CML) patients, tyrosine kinase inhibitors (TKIs) may select for drug-resistant BCR-ABL1 kinase domain (KD) mutants. Although…”
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Drug resistance and BCR‐ABL kinase domain mutations in Philadelphia chromosome–positive acute lymphoblastic leukemia from the imatinib to the second‐generation tyrosine kinase inhibitor era: The main changes are in the type of mutations, but not in the frequency of mutation involvement by Soverini, Simona, De Benedittis, Caterina, Papayannidis, Cristina, Paolini, Stefania, Venturi, Claudia, Iacobucci, Ilaria, Luppi, Mario, Bresciani, Paola, Salvucci, Marzia, Russo, Domenico, Sica, Simona, Orlandi, Ester, Intermesoli, Tamara, Gozzini, Antonella, Bonifacio, Massimiliano, Rigolin, Gian Matteo, Pane, Fabrizio, Baccarani, Michele, Cavo, Michele, Martinelli, Giovanni

“…BACKGROUND Patients with Philadelphia chromosome–positive (Ph+) acute lymphoblastic leukemia (ALL) frequently relapse on imatinib with acquisition of BCR‐ABL…”
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Next-generation deep sequencing improves detection of BCR-ABL1 kinase domain mutations emerging under tyrosine kinase inhibitor treatment of chronic myeloid leukemia patients in chronic phase by Machova Polakova, Katerina, Kulvait, Vojtech, Benesova, Adela, Linhartova, Jana, Klamova, Hana, Jaruskova, Monika, de Benedittis, Caterina, Haferlach, Torsten, Baccarani, Michele, Martinelli, Giovanni, Stopka, Tomas, Ernst, Thomas, Hochhaus, Andreas, Kohlmann, Alexander, Soverini, Simona

“…Purpose Here, we studied whether amplicon next-generation deep sequencing (NGS) could improve the detection of emerging BCR - ABL1 kinase domain mutations in…”
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Transarterial radioembolization in patients with hepatocellular carcinoma of intermediate B2 substage by Cappelli, Alberta, Sangro, Paloma, Mosconi, Cristina, Deppe, Iris, Terzi, Eleonora, Bilbao, Jose I., Rodriguez-Fraile, Macarena, De Benedittis, Caterina, Ricke, Jens, Golfieri, Rita, Sangro, Bruno

“…Purpose Patients with hepatocellular carcinoma (HCC) of intermediate stage (BCLC-B according to the Barcelona Clinic Liver Cancer classification) are a…”
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Diagnostic Accuracy of North America Expert Consensus Statement on Reporting CT Findings in Patients Suspected of Having COVID-19 Infection: An Italian Single-Center Experience by Ciccarese, Federica, Coppola, Francesca, Spinelli, Daniele, Galletta, Giovanni Luca, Lucidi, Vincenzo, Paccapelo, Alexandro, De Benedittis, Caterina, Balacchi, Caterina, Golfieri, Rita

“…To evaluate the diagnostic accuracy of the four standardized categories for CT reporting proposed by the Radiological Society of North America (RSNA) to…”
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