Search Results - "De A. Lima, Ana Paula C."

Protease activated receptor signaling is required for African trypanosome traversal of human brain microvascular endothelial cells by Grab, Dennis J, Garcia-Garcia, Jose C, Nikolskaia, Olga V, Kim, Yuri V, Brown, Amanda, Pardo, Carlos A, Zhang, Yongqing, Becker, Kevin G, Wilson, Brenda A, de A Lima, Ana Paula C, Scharfstein, Julio, Dumler, J Stephen

“…Using human brain microvascular endothelial cells (HBMECs) as an in vitro model for how African trypanosomes cross the human blood-brain barrier (BBB) we…”
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Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease by Nikolskaia, Olga V, de A Lima, Ana Paula C, Kim, Yuri V, Lonsdale-Eccles, John D, Fukuma, Toshihide, Scharfstein, Julio, Grab, Dennis J

“…In this study we investigated why bloodstream forms of Trypanosoma brucei gambiense cross human brain microvascular endothelial cells (BMECs), a human…”
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Cloning and characterization of the phosphoglucomutase of Trypanosoma cruzi and functional complementation of a Saccharomyces cerevisiae PGM null mutant by Penha, Luciana L, Mendonça-Previato, Lucia, Previato, Jose O, Scharfstein, Julio, Heise, Norton, Lima, Ana Paula C. de A

“…Trypanosoma cruzi is the etiological agent of Chagas' disease, a chronic illness characterized by progressive cardiomyopathy and/or denervation of the…”
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The substrate specificity of cruzipain 2, a cysteine protease isoform from Trypanosoma cruzi by Dos Reis, Flavia C. G., Júdice, Wagner A. S., Juliano, Maria A., Juliano, Luiz, Scharfstein, Julio, De A. Lima, Ana Paula C.

“…Abstract Papain-like cysteine proteases are important for the survival of the flagellated protozoa Trypanosoma cruzi, the causative agent of Chagas' Disease…”
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Chagasin, the endogenous cysteine-protease inhibitor of Trypanosoma cruzi, modulates parasite differentiation and invasion of mammalian cells by Santos, Camila C, Sant'Anna, Celso, Terres, Amanda, Cunha-e-Silva, Narcisa L, Scharfstein, Julio, de A. Lima, Ana Paula C

“…Chagasin is a Trypanosoma cruzi protein that was recently characterized as a tight-binding inhibitor of papain-like cysteine proteases (CPs). Considering that…”
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Role of chagasin-like inhibitors as endogenous regulators of cysteine proteases in parasitic protozoa by SANTOS, Camila C, SCHARFSTEIN, Julio, LIMA, Ana Paula C. De A

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Blood-brain barrier traversal by African trypanosomes requires calcium signaling induced by parasite cysteine protease by Nikolskaia, Olga V., de A. Lima, Ana Paula C., Kim, Yuri V., Lonsdale-Eccles, John D., Fukuma, Toshihide, Scharfstein, Julio, Grab, Dennis J.

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Altered expression of cruzipain and a cathepsin B-like target in a Trypanosoma cruzi cell line displaying resistance to synthetic inhibitors of cysteine-proteinases by Yong, Vladimir, Schmitz, Verônica, Vannier-Santos, Marcos André, de A. Lima, Ana Paula C, Lalmanach, Gilles, Juliano, Luiz, Gauthier, Francis, Scharfstein, Julio

“…The therapeutic potential of synthetic inhibitors to the major cysteine-proteinase from Trypanosoma cruzi (cruzain or cruzipain) was recently demonstrated in…”
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Identification of new cysteine protease gene isoforms in Trypanosoma cruzi by Lima, A P, Tessier, D C, Thomas, D Y, Scharfstein, J, Storer, A C, Vernet, T

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