Search Results - "De Vincentis, Antonio"
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Molecular and histological traits of reduced lysosomal acid lipase activity in the fatty liver
Published in Cell death & disease (18-11-2021)“…Recent studies demonstrated reduced blood lysosomal acid lipase (LAL) activity in patients with nonalcoholic fatty liver disease (NAFLD). We aimed to verify…”
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Hepatitis C virus and metabolic disorder interactions towards liver damage and atherosclerosis
Published in World journal of gastroenterology : WJG (21-03-2014)“…Hepatitis C virus(HCV)is one of the main causes of liver disease worldwide,and alterations of glucose metabolism have reached pandemic proportions in western…”
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3
Low Alanine Aminotransferase Levels in the Elderly Population: Frailty, Disability, Sarcopenia, and Reduced Survival
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (14-06-2018)“…Although low alanine aminotransferase (ALT) levels have been associated with poor outcomes in the elderly population, the determinants subtending this…”
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Exhaled breath analysis in hepatology: State-of-the-art and perspectives
Published in World journal of gastroenterology : WJG (14-08-2019)“…Liver disease is characterized by breath exhalation of peculiar volatile organic compounds (VOCs). Thanks to the availability of sensitive technologies for…”
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Impact of Low Muscle Mass and Low Muscle Strength According to EWGSOP2 and EWGSOP1 in Community-Dwelling Older People
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (18-06-2020)“…Abstract Background A universal definition of sarcopenia is still lacking. Since the European criteria have been recently revised, we aimed at studying…”
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Microarray-based Detection of Critical Overexpressed Genes in the Progression of Hepatic Fibrosis in Non-alcoholic Fatty Liver Disease: A Protein-protein Interaction Network Analysis
Published in Current medicinal chemistry (01-01-2024)“…Non-alcoholic fatty liver disease (NAFLD) is a prevalent cause of chronic liver disease and encompasses a broad spectrum of disorders, including simple…”
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Prevalence, risk factors, and treatment of anemia in hospitalized older patients across geriatric and nephrological settings in Italy
Published in Scientific reports (24-08-2024)“…Anemia is a common but often underdiagnosed and undertreated geriatric syndrome in hospitalized older patients. In this retrospective multicenter study, we…”
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Non-alcoholic fatty liver disease and steatohepatitis: State of the art on effective therapeutics based on the gold standard method for diagnosis
Published in Molecular metabolism (Germany) (01-08-2021)“…The prevalence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (NAFLD/NASH) is increasing. NAFLD/NASH may progress to cirrhosis and…”
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Association between non-invasive liver fibrosis scores and occurrence of health adverse outcomes in older people
Published in Digestive and liver disease (01-09-2019)“…The relation between liver fibrosis scores and health outcomes in older people has been barely investigated. We aimed to evaluate the association of four liver…”
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Poor accuracy and sustainability of the first‐step FIB4 EASL pathway for stratifying steatotic liver disease risk in the general population
Published in Alimentary pharmacology & therapeutics (01-06-2024)“…Summary Background and Aims The European Association for the Study of the Liver introduced a clinical pathway (EASL CP) for screening significant/advanced…”
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Neurotrophic keratopathy: Pros and cons of current treatments
Published in The ocular surface (01-10-2019)“…Several therapeutics have been proposed for neurotrophic keratitis, but no direct comparison among different approaches is available. To compare…”
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Metabolic and genetic determinants for progression to severe liver disease in subjects with obesity from the UK Biobank
Published in International Journal of Obesity (01-03-2022)“…Background Obesity is among the main determinants of nonalcoholic fatty liver disease progression towards severe liver disease (SLD). However, risk factors for…”
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Combined evaluation of aminotransferases improves risk stratification for overall and cause-specific mortality in older patients
Published in Aging clinical and experimental research (01-12-2021)“…Background Recent studies identified low levels of alanine aminotransferase (ALT) as strong predictors of mortality in older people. Aims Here we verified if…”
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Voltammetric analysis for distinguishing portal hypertension-related from malignancy-related ascites: A proof of concept study
Published in PloS one (21-05-2020)“…Serum-ascites albumin gradient (SAAG) remains the most sensitive and specific marker for the differentiation of ascites due to portal hypertension from ascites…”
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Orthogeriatric co-management for the care of older subjects with hip fracture: recommendations from an Italian intersociety consensus
Published in Aging clinical and experimental research (01-09-2021)“…Background Health outcomes of older subjects with hip fracture (HF) may be negatively influenced by multiple comorbidities and frailty. An integrated…”
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Prevalence, clinical characteristics, and disease burden of chronic cough in Italy: a cross-sectional study
Published in BMC pulmonary medicine (20-06-2024)“…Chronic cough has been associated with reduced health-related quality of life, negative impacts on sleep, work, and other daily activities, and increased use…”
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Management of hip fracture in the older people: rationale and design of the Italian consensus on the orthogeriatric co-management
Published in Aging clinical and experimental research (01-07-2020)“…Background Hip fracture (HF) is a burdening health problem in older people. The orthogeriatric approach has been shown to favour functional recovery and reduce…”
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Real-world experience with obeticholic acid in patients with primary biliary cholangitis
Published in JHEP reports (01-04-2021)“…Obeticholic acid (OCA) is the second-line treatment approved for patients with primary biliary cholangitis (PBC) and an inadequate response or intolerance to…”
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Lysosomal Acid Lipase Activity Is Reduced Both in Cryptogenic Cirrhosis and in Cirrhosis of Known Etiology
Published in PloS one (24-05-2016)“…Liver cirrhosis is characterized by a severe acquired reduction of LAL-activity, the precise causes and consequences of which need to be further addressed…”
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