Search Results - "De Simone, Marco"
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The coding and long noncoding single-cell atlas of the developing human fetal striatum
Published in Science (American Association for the Advancement of Science) (07-05-2021)“…Deciphering how the human striatum develops is necessary for understanding the diseases that affect this region. To decode the transcriptional modules that…”
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Modal Coupling in Presence of Dry Friction
Published in Machines (Basel) (01-03-2018)“…In this paper, we analyze the behavior of a single pad system in the presence of dry friction. The goal is to investigate the path that leads a stable…”
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Unmanned Ground Vehicle Modelling in Gazebo/ROS-Based Environments
Published in Machines (Basel) (01-06-2019)“…The fusion of different technologies is the base of the fourth industrial revolution. Companies are encouraged to integrate new tools in their production…”
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4
Obstacle Avoidance System for Unmanned Ground Vehicles by Using Ultrasonic Sensors
Published in Machines (Basel) (01-06-2018)“…Artificial intelligence is the ability of a computer to perform the functions and reasoning typical of the human mind. In its purely informatic aspect, it…”
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Single Cell T Cell Receptor Sequencing: Techniques and Future Challenges
Published in Frontiers in immunology (18-07-2018)“…The peculiarity of T cell is their ability to recognize an infinite range of self and foreign antigens. This ability is achieved during thymic development…”
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Itch/AIP4 Associates with and Promotes p63 Protein Degradation
Published in Cell cycle (Georgetown, Tex.) (15-08-2006)“…P63, a protein related to the tumor suppressor p53, is a transcription factor that plays an important role in epidermal differentiation and limb development…”
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Transcriptional Landscape of Human Tissue Lymphocytes Unveils Uniqueness of Tumor-Infiltrating T Regulatory Cells
Published in Immunity (Cambridge, Mass.) (15-11-2016)“…Tumor-infiltrating regulatory T lymphocytes (Treg) can suppress effector T cells specific for tumor antigens. Deeper molecular definitions of…”
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p63 is a cereblon substrate involved in thalidomide teratogenicity
Published in Nature chemical biology (01-11-2019)“…Cereblon (CRBN) is a primary target of thalidomide and mediates its multiple pharmacological activities, including teratogenic and antimyeloma activities. CRBN…”
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Multibody modeling and nonlinear control of the pantograph/catenary system
Published in Archive of applied mechanics (1991) (15-08-2019)“…In this paper, a closed-chain multibody model of a pantograph/catenary system is developed and used for the optimal design of a nonlinear controller based on…”
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Circulating microRNAs are new and sensitive biomarkers of myocardial infarction
Published in European heart journal (01-11-2010)“…Aims Circulating microRNAs (miRNAs) may represent a novel class of biomarkers; therefore, we examined whether acute myocardial infarction (MI) modulates miRNAs…”
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Clonally expanded EOMES+ Tr1-like cells in primary and metastatic tumors are associated with disease progression
Published in Nature immunology (01-06-2021)“…Regulatory T (T reg ) cells are a barrier for tumor immunity and a target for immunotherapy. Using single-cell transcriptomics, we found that CD4 + T cells…”
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Metabolic targeting of cancer associated fibroblasts overcomes T-cell exclusion and chemoresistance in soft-tissue sarcomas
Published in Nature communications (20-03-2024)“…T cell-based immunotherapies have exhibited promising outcomes in tumor control; however, their efficacy is limited in immune-excluded tumors…”
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Combined PD-L1/TGFβ blockade allows expansion and differentiation of stem cell-like CD8 T cells in immune excluded tumors
Published in Nature communications (05-08-2023)“…TGFβ signaling is associated with non-response to immune checkpoint blockade in patients with advanced cancers, particularly in the immune-excluded phenotype…”
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circCsnk1g3- and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment
Published in Nature communications (25-11-2022)“…Exonic circular RNAs (circRNAs) produce predominantly non-coding RNA species that have been recently profiled in many tumors. However, their functional…”
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Design of a Non-Back-Drivable Screw Jack Mechanism for the Hitch Lifting Arms of Electric-Powered Tractors
Published in Actuators (01-12-2022)“…The agricultural sector is constantly evolving. The rise in the world’s population generates an increasingly growing demand for food, resulting in the need for…”
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PRGdb: a bioinformatics platform for plant resistance gene analysis
Published in Nucleic acids research (01-01-2010)“…PRGdb is a web accessible open-source (http://www.prgdb.org) database that represents the first bioinformatic resource providing a comprehensive overview of…”
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Non-Prehensile Manipulation Actions and Visual 6D Pose Estimation for Fruit Grasping Based on Tactile Sensing
Published in Robotics (Basel) (01-08-2023)“…Robotic manipulation in cluttered environments is one of the challenges roboticists are currently facing. When the objects to handle are delicate fresh fruits,…”
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Induction of a distinct macrophage population and protection from lung injury and fibrosis by Notch2 blockade
Published in Nature communications (06-11-2024)“…Macrophages are pleiotropic and diverse cells that populate all tissues of the body. Besides tissue-specific resident macrophages such as alveolar macrophages,…”
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Lack of Methyl-CpG Binding Protein 2 (MeCP2) Affects Cell Fate Refinement During Embryonic Cortical Development
Published in Cerebral cortex (New York, N.Y. 1991) (01-05-2018)“…Abstract During differentiation, neurons progressively restrict their fate repressing the expression of specific genes. Here we describe the involvement in…”
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Experimental Comparison of Two 6D Pose Estimation Algorithms in Robotic Fruit-Picking Tasks
Published in Robotics (Basel) (01-09-2024)“…This paper presents an experimental comparison between two existing methods representative of two categories of 6D pose estimation algorithms nowadays commonly…”
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