Search Results - "De, Bundel D"
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Dopamine D2 receptors gate generalization of conditioned threat responses through mTORC1 signaling in the extended amygdala
Published in Molecular psychiatry (01-11-2016)“…Overgeneralization of conditioned threat responses is a robust clinical marker of anxiety disorders. In overgeneralization, responses that are appropriate to…”
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Dysfunctional astrocytic regulation of glutamate transmission in a rat model of depression
Published in Molecular psychiatry (01-05-2013)“…Depression is usually associated with alterations in the monoaminergic system. However, new evidences suggest the involvement of the glutamatergic system in…”
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Optical activation of endogenous metabotropic glutamate receptor 4 (mGlu4) in the amygdala dynamically regulates symptoms associated with persistent inflammatory pain
Published in Molecular Psychiatry (01-03-2018)Get full text
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Dynamic modulation of inflammatory pain-related affective and sensory symptoms by optical control of amygdala metabotropic glutamate receptor 4
Published in Molecular psychiatry (01-03-2018)“…Contrary to acute pain, chronic pain does not serve as a warning signal and must be considered as a disease per se . This pathology presents a sensory and…”
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Effects of disrupted ghrelin receptor function on fear processing, anxiety and saccharin preference in mice
Published in Psychoneuroendocrinology (01-12-2019)“…•Exposure to a high-fat diet reduces ghrelin receptor function.•Exposure to a high-fat diet does not alter fear or anxiety-like behaviour but lowers saccharin…”
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Antidepressant Drugs Specifically Inhibiting Noradrenaline Reuptake Enhance Recognition Memory in Rats
Published in Behavioral neuroscience (01-12-2015)“…Patients suffering from major depression often experience memory deficits even after the remission of mood symptoms, and many antidepressant drugs do not…”
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Slc7a11 (xCT) protein expression is not altered in the depressed brain and system xc- deficiency does not affect depression-associated behaviour in the corticosterone mouse model
Published in The world journal of biological psychiatry (28-05-2019)“…Objectives: The cystine/glutamate antiporter (system xc-) is believed to contribute to nonvesicular glutamate release from glial cells in various brain areas…”
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Spatial distribution of D1R- and D2R-expressing medium-sized spiny neurons differs along the rostro-caudal axis of the mouse dorsal striatum
Published in Frontiers in neural circuits (2013)“…The striatum projection neurons are striatonigral and striatopallidal medium-sized spiny neurons (MSNs) that preferentially express D1 (D1R) and D2 (D2R)…”
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Trans-Modulation of the Somatostatin Type 2A Receptor Trafficking by Insulin-Regulated Aminopeptidase Decreases Limbic Seizures
Published in The Journal of neuroscience (26-08-2015)“…Within the hippocampus, the major somatostatin (SRIF) receptor subtype, the sst2A receptor, is localized at postsynaptic sites of the principal neurons where…”
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P.2.018 Antidepressants specifically inhibiting noradrenaline reuptake enhance recognition memory in rats
Published in European neuropsychopharmacology (01-03-2012)Get full text
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Deletion of insulin-regulated aminopeptidase in mice decreases susceptibility to pentylenetetrazol-induced generalized seizures
Published in Seizure (London, England) (01-10-2011)“…Abstract The peptide angiotensin IV (Ang IV) influences seizure susceptibility in rat and mouse models. Indeed, Ang IV has been shown to protect rats from…”
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Fear modulation by transcranial direct current stimulation
Published in Brain stimulation (01-03-2019)Get full text
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Accelerated high-frequency repetitive transcranial magnetic stimulation positively influences the behavior, monoaminergic system, and cerebral perfusion in anxious aggressive dogs: A case study
Published in Journal of veterinary behavior (01-09-2019)“…Accelerated high-frequency repetitive transcranial magnetic stimulation (aHF-rTMS) was proven to produce fast clinical effects in humans suffering from…”
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Acute accelerated high frequency TMS augments homovanillic acid and 3,4-dihydroxyphenylacetic acid in the cerebrospinal fluid of healthy dogs
Published in Brain stimulation (01-03-2019)Get full text
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Hippocampal and prefrontal dopamine D1/5 receptor involvement in the memory-enhancing effect of reboxetine
Published in The international journal of neuropsychopharmacology (01-10-2013)“…Dopamine modulates cognitive functions through regulation of synaptic transmission and plasticity in the hippocampus and prefrontal cortex (PFC). Thus,…”
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Angiotensin IV and LVV-haemorphin 7 enhance spatial working memory in rats: Effects on hippocampal glucose levels and blood flow
Published in Neurobiology of learning and memory (01-07-2009)“…The IRAP ligands Angiotensin IV (Ang IV) and LVV-haemorphin 7 (LVV-H7) enhance performance in a range of memory paradigms in normal rats and ameliorate memory…”
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Hippocampal sst1 receptors are autoreceptors and do not affect seizures in rats
Published in Neuroreport (10-03-2010)“…Somatostatin-14 (SRIF-14) exerts anticonvulsive effects in several rat seizure models, generally attributed to sst2 receptor activation. Whereas sst1…”
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Involvement of insulin-regulated aminopeptidase and/or aminopeptidase N in the angiotensin IV-induced effect on dopamine release in the striatum of the rat
Published in Brain research (02-02-2007)“…Abstract Locally administered angiotensin IV causes a dose-dependent increase of the dopamine levels in the striatum of the rat. The aminopeptidases…”
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Loss of system x(c)- does not induce oxidative stress but decreases extracellular glutamate in hippocampus and influences spatial working memory and limbic seizure susceptibility
Published in The Journal of neuroscience (13-04-2011)“…System x(c)- exchanges intracellular glutamate for extracellular cystine, giving it a potential role in intracellular glutathione synthesis and nonvesicular…”
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