Search Results - "Daza, Ray"

Pax6, Tbr2, and Tbr1 Are Expressed Sequentially by Radial Glia, Intermediate Progenitor Cells, and Postmitotic Neurons in Developing Neocortex by Englund, Chris, Fink, Andy, Lau, Charmaine, Pham, Diane, Daza, Ray A. M, Bulfone, Alessandro, Kowalczyk, Tom, Hevner, Robert F

“…The developing neocortex contains two types of progenitor cells for glutamatergic, pyramidal-projection neurons. The first type, radial glia, produce neurons…”
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Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity by Mihalas, Anca B., Elsen, Gina E., Bedogni, Francesco, Daza, Ray A.M., Ramos-Laguna, Kevyn A., Arnold, Sebastian J., Hevner, Robert F.

“…Intermediate progenitors (IPs) amplify the production of pyramidal neurons, but their role in selective genesis of cortical layers or neuronal subtypes remains…”
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Intermediate Neuronal Progenitors (Basal Progenitors) Produce Pyramidal–Projection Neurons for All Layers of Cerebral Cortex by Kowalczyk, Tom, Pontious, Adria, Englund, Chris, Daza, Ray A. M., Bedogni, Francesco, Hodge, Rebecca, Attardo, Alessio, Bell, Chris, Huttner, Wieland B., Hevner, Robert F.

“…The developing cerebral cortex contains apical and basal types of neurogenic progenitor cells. Here, we investigated the cellular properties and neurogenic…”
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Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex by Bedogni, Francesco, Hodge, Rebecca D., Elsen, Gina E., Nelson, Branden R., Daza, Ray A. M., Beyer, Richard P., Bammler, Theo K., Rubenstein, John L. R., Hevner, Robert F., Rakic, Pasko

“…Areas and layers of the cerebral cortex are specified by genetic programs that are initiated in progenitor cells and then, implemented in postmitotic neurons…”
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Transcription factors in glutamatergic neurogenesis: Conserved programs in neocortex, cerebellum, and adult hippocampus by Hevner, Robert F., Hodge, Rebecca D., Daza, Ray A.M., Englund, Chris

“…Glutamatergic, pyramidal-projection neurons are produced in the embryonic cerebral cortex by a series of genetically programmed fate choices, implemented in…”
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Dystroglycan on Radial Glia End Feet Is Required for Pial Basement Membrane Integrity and Columnar Organization of the Developing Cerebral Cortex by Myshrall, Timothy D, Moore, Steven A, Ostendorf, Adam P, Satz, Jakob S, Kowalczyk, Tom, Nguyen, Huy, Daza, Ray A.M, Lau, Charmaine, Campbell, Kevin P, Hevner, Robert F

“…ABSTRACTInteractions between the embryonic pial basement membrane (PBM) and radial glia (RG) are essential for morphogenesis of the cerebral cortex because…”
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Development of the Deep Cerebellar Nuclei: Transcription Factors and Cell Migration from the Rhombic Lip by Fink, Andrew J, Englund, Chris, Daza, Ray A. M, Pham, Diane, Lau, Charmaine, Nivison, Mary, Kowalczyk, Tom, Hevner, Robert F

“…The deep cerebellar nuclei (DCN) are the main output centers of the cerebellum, but little is known about their development. Using transcription factors as…”
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Intermediate progenitors support migration of neural stem cells into dentate gyrus outer neurogenic niches by Nelson, Branden R, Hodge, Rebecca D, Daza, Ray Am, Tripathi, Prem Prakash, Arnold, Sebastian J, Millen, Kathleen J, Hevner, Robert F

“…The hippocampal dentate gyrus (DG) is a unique brain region maintaining neural stem cells (NCSs) and neurogenesis into adulthood. We used multiphoton imaging…”
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Unipolar Brush Cells of the Cerebellum Are Produced in the Rhombic Lip and Migrate through Developing White Matter by Englund, Chris, Kowalczyk, Tom, Daza, Ray A. M, Dagan, Avner, Lau, Charmaine, Rose, Matthew F, Hevner, Robert F

“…Unipolar brush cells (UBCs) are glutamatergic interneurons in the cerebellar cortex and dorsal cochlear nucleus. We studied the development of UBCs, using…”
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AUTS2 Regulates RNA Metabolism and Dentate Gyrus Development in Mice by Castanza, Anthony S, Ramirez, Sanja, Tripathi, Prem P, Daza, Ray A M, Kalume, Franck K, Ramirez, Jan-Marino, Hevner, Robert F

“…Abstract Human AUTS2 mutations are linked to a syndrome of intellectual disability, autistic features, epilepsy, and other neurological and somatic disorders…”
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Homozygous Mutations in CSF1R Cause a Pediatric-Onset Leukoencephalopathy and Can Result in Congenital Absence of Microglia by Oosterhof, Nynke, Chang, Irene J., Karimiani, Ehsan Ghayoor, Kuil, Laura E., Jensen, Dana M., Daza, Ray, Young, Erica, Astle, Lee, van der Linde, Herma C., Shivaram, Giridhar M., Demmers, Jeroen, Latimer, Caitlin S., Keene, C. Dirk, Loter, Emily, Maroofian, Reza, van Ham, Tjakko J., Hevner, Robert F., Bennett, James T.

“…Microglia are CNS-resident macrophages that scavenge debris and regulate immune responses. Proliferation and development of macrophages, including microglia,…”
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protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map by Elsen, Gina E., Hodge, Rebecca D., Bedogni, Francesco, Daza, Ray A. M., Nelson, Branden R., Shiba, Naoko, Reiner, Steven L., Hevner, Robert F.

“…The cortical area map is initially patterned by transcription factor (TF) gradients in the neocortical primordium, which define a “protomap” in the embryonic…”
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Breast cancer cell-secreted miR-199b-5p hijacks neurometabolic coupling to promote brain metastasis by Ruan, Xianhui, Yan, Wei, Cao, Minghui, Daza, Ray Anthony M., Fong, Miranda Y., Yang, Kaifu, Wu, Jun, Liu, Xuxiang, Palomares, Melanie, Wu, Xiwei, Li, Arthur, Chen, Yuan, Jandial, Rahul, Spitzer, Nicholas C., Hevner, Robert F., Wang, Shizhen Emily

“…Breast cancer metastasis to the brain is a clinical challenge rising in prevalence. However, the underlying mechanisms, especially how cancer cells adapt a…”
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Unipolar (Dendritic) Brush Cells Are Morphologically Complex and Require Tbr2 for Differentiation and Migration by McDonough, Ashley, Elsen, Gina E, Daza, Ray M, Bachleda, Amelia R, Pizzo, Donald, DelleTorri, Olivia M, Hevner, Robert F

“…Previous studies demonstrated specific expression of transcription factor Tbr2 in unipolar brush cells (UBCs) of the cerebellum during development and…”
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Effects of Lipopolysaccharide and Progesterone Exposures on Embryonic Cerebral Cortex Development in Mice by Tronnes, Ashlie A, Koschnitzky, Jenna, Daza, Ray, Hitti, Jane, Ramirez, Jan Marino, Hevner, Robert

“…Our objective was to determine if progesterone pretreatment could ameliorate the detrimental effects of lipopolysaccharide (LPS)-induced inflammation on…”
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Autism susceptibility candidate 2 ( Auts2) encodes a nuclear protein expressed in developing brain regions implicated in autism neuropathology by Bedogni, Francesco, Hodge, Rebecca D., Nelson, Branden R., Frederick, Erika A, Shiba, Naoko, Daza, Ray A., Hevner, Robert F.

“…Autism susceptibility candidate 2 ( Auts2) is a gene associated with autism and mental retardation, whose function is unknown. Expression of Auts2 mRNA and…”
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Developmental exposure to diesel exhaust upregulates transcription factor expression, decreases hippocampal neurogenesis, and alters cortical lamina organization: relevance to neurodevelopmental disorders by Cole, Toby B, Chang, Yu-Chi, Dao, Khoi, Daza, Ray, Hevner, Robert, Costa, Lucio G

“…Exposure to traffic-related air pollution (TRAP) during development and/or in adulthood has been associated in many human studies with both neurodevelopmental…”
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Neuropathologic Features of Pontocerebellar Hypoplasia Type 6 by Joseph, Jeffrey T, Innes, A Micheil, Smith, Amanda C, Vanstone, Megan R, Schwartzentruber, Jeremy A, Bulman, Dennis E, Majewski, Jacek, Daza, Ray A, Hevner, Robert F, Michaud, Jean, Boycott, Kym M

“…ABSTRACTPontocerebellar hypoplasia is a group of severe developmental disorders with prenatal onset affecting the growth and function of the brainstem and…”
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A dual‐fluorescence reporter in the Eomes locus for live imaging and medium‐term lineage tracing by Probst, Simone, Daza, Ray A., Bader, Natalie, Hummel, Jonas F., Weiß, Matthias, Tanriver, Yakup, Hevner, Robert F., Arnold, Sebastian J.

“…Summary The T‐box transcription factor Eomes (also known as Tbr2) shows short‐lived expression in various localized domains of the embryo, including epiblast…”
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Beyond laminar fate: toward a molecular classification of cortical projection/pyramidal neurons by Hevner, Robert F, Daza, Ray A M, Rubenstein, John L R, Stunnenberg, Henk, Olavarria, Jaime F, Englund, Chris

“…Cortical projection neurons exhibit diverse morphological, physiological, and molecular phenotypes, but it is unknown how many distinct types exist. Many…”
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