Search Results - "Day, Judy D"
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Divergent COVID-19 Disease Trajectories Predicted by a DAMP-Centered Immune Network Model
Published in Frontiers in immunology (28-10-2021)“…COVID-19 presentations range from mild to moderate through severe disease but also manifest with persistent illness or viral recrudescence. We hypothesized…”
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2
Mathematical Modeling of Early Cellular Innate and Adaptive Immune Responses to Ischemia/Reperfusion Injury and Solid Organ Allotransplantation
Published in Frontiers in immunology (25-09-2015)“…A mathematical model of the early inflammatory response in transplantation is formulated with ordinary differential equations. We first consider the…”
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3
Solving Immunology?
Published in Trends in immunology (01-02-2017)“…Emergent responses of the immune system result from the integration of molecular and cellular networks over time and across multiple organs. High-content and…”
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Self-harm to preferentially harm the pathogens within: non-specific stressors in innate immunity
Published in Proceedings of the Royal Society. B, Biological sciences (13-04-2016)“…Therapies with increasing specificity against pathogens follow the immune system's evolutionary course in maximizing host defence while minimizing self-harm…”
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5
Pathogen transfer through environment–host contact: an agent-based queueing theoretic framework
Published in Mathematical medicine and biology (11-09-2018)“…Abstract Queueing theory studies the properties of waiting queues and has been applied to investigate direct host-to-host transmitted disease dynamics, but its…”
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Inflammation and disease: Modelling and modulation of the inflammatory response to alleviate critical illness
Published in Current opinion in systems biology (01-12-2018)“…Critical illness, a constellation of interrelated inflammatory and physiological derangements occurring subsequent to severe infection or injury, affects a…”
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Combining robust state estimation with nonlinear model predictive control to regulate the acute inflammatory response to pathogen
Published in Mathematical biosciences and engineering : MBE (01-10-2015)“…The inflammatory response aims to restore homeostasis by means of removing a biological stress, such as an invading bacterial pathogen. In cases of acute…”
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Journal Article -
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Self-harm to preferentially harm the pathogens within: non-specific stressors in innate immunity
Published in Proceedings of the Royal Society. B, Biological sciences (13-04-2016)“…Therapies with increasing specificity against pathogens follow the immune system's evolutionary course in maximizing host defence while minimizing self-harm…”
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Journal Article -
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Mathematical approaches to modeling, understanding, and controlling the acute inflammatory response to pathogen and endotoxin
Published 01-01-2007“…This thesis includes work dealing with topics related to the modeling, understanding, and controlling the acute inflammatory response. After the introductory…”
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Dissertation