Search Results - "Day, I.N.M."

IGF2BP1 , IGF2BP2 and IGF2BP3 genotype, haplotype and genetic model studies in metabolic syndrome traits and diabetes by Rodriguez, S, Eiriksdottir, G, Gaunt, T.R, Harris, T.B, Launer, L.J, Gudnason, V, Day, I.N.M

“…Abstract Objective Genetic variation at the insulin-like binding protein 2 ( IGF2BP2 ) gene has been associated with type 2 diabetes (T2D) by genome-wide…”
Get full text

Level of Ex Vivo Interleukin 6 Expression in Human Peripheral Fat Compared with Other Tissues by Sonnenberg, S, Shearman, C.P, Baxter, S, Morris, G.E, Cumming, D.V.E, Montgomery, H.E, Rose-Zerilli, M.J, Day, I.N.M

“…Objectives Adipose tissue is able to secrete a variety of active mediators into the circulation. One of these is Interleukin 6 (IL6). IL6 may play a causal…”
Get full text

Evidence for a third genetic locus causing familial hypercholesterolemia. A non-LDLR, non-APOB kindred by Haddad, L, Day, I N, Hunt, S, Williams, R R, Humphries, S E, Hopkins, P N

“…Monogenically inherited hypercholesterolemia is most commonly caused by mutations at the low density lipoprotein receptor (LDLR) locus causing familial…”
Get full text

Effect of vitamin D receptor gene on prostate cancer progression: genetic association study and meta-analysis by Chen, L, Smith, G.D, Donovan, J, Neal, D.E, Hamdy, F.C, Cox, A, Day, I.N.M, Rodriguez, S, Davis, M, Lewis, S.J

Get full text

A mitochondrial DNA sequence variant associated with schizophrenia and oxidative stress by Marchbanks, R.M., Ryan, Margaret, Day, I.N.M., Owen, M., McGuffin, P., Whatley, S.A.

“…We have previously reported a changed mitochondrial ( mt) gene expression in brain from patients with schizophrenia [Schizophr. Res. 14 (1995) 203]; now, we…”
Get full text

Electrophoresis for genotyping: microtiter array diagonal gel electrophoresis on horizontal polyacrylamide gels, hydrolink, or agarose by Day, I N, Humphries, S E

“…Electrophoresis of DNA has been performed traditionally in either an agarose or acrylamide gel matrix. Considerable effort has been directed to improved…”
Get more information

IGF1, growth pathway polymorphisms and schizophrenia: A pooling study by Gunnell, D., Lewis, S., Wilkinson, J., Georgieva, L., Davey, G. Smith, Day, I.N.M., Holly, J.M.P., O'Donovan, M.C., Owen, M.J., Kirov, G., Zammit, S.

“…It has been hypothesized that insulin‐like growth factors (IGFs) and components of the growth‐hormone (GH)‐IGF axis may underlie reported associations of poor…”
Get full text

Spectrum of LDL receptor gene mutations in heterozygous familial hypercholesterolemia by Day, INM, Whittall, RA, O'Dell, SD, Haddad, L, Bolla, MK, Gudnason, V, Humphries, SE

“…Familial hypercholesterolemia by usual definition reflects mutations of the LDL‐receptor gene. Extensive molecular characterization of mutations ascertained…”
Get full text

Gene environment interaction in determining risk of ischaemic heart disease by Humphries, S.E., Talmud, P.J., Cooper, J., Waterworth, D.M., Day, I.N.M., Miller, G.J.

Get full text

Evidence for a third genetic locus causing familial hypercholesterolemia: a non-LDLR, non-APOB kindred1 by L. Haddad, I.N.M. Day, S. Hunt, R.R. Williams, S.E. Humphries, P.N. Hopkins

“…Monogenically inherited hypercholesterolemia is most commonly caused by mutations at the low density lipoprotein receptor (LDLR) locus causing familial…”
Get full text

A study of mitochondrial DNA mutations in peripheral lymphocytes in an aging cohort by Zhang, B, Ye, S, Sayer, A A, Hammans, S R, Adio, S, Hinks, L J, Smythe, P J, Groot, D, Cooper, C, Day, I N M

“…Somatic mutation in the mitochondrial genome occurs much more rapidly than in the nuclear genome and is a feature, possibly contributory, of the aging of cells…”
Get more information

Patterns of DNA methylation of the parathyroid hormone-related protein gene in human lung carcinoma by Ganderton, R.H., Day, I.N.M., Briggs, R.S.J.

“…Humoral hypercalcaemia of malignancy often results from production of parathyroid hormone-related protein (PTHrP) by the tumour. We have investigated whether…”
Get full text

Analysis of the association of a heat shock protein70-1 gene promoter polymorphism with myocardial infarction and coronary risk traits by BOLLA, M. K, MILLER, G. J, DAY, I. N. M, YELLON, D. M, EVANS, A, LUC, G, CAMBOU, J. P, ARVEILER, D, CAMBIEN, F, LATCHMAN, D. S, HUMPHRIES, S. E

“…Heat shock proteins (HSP) are induced during coronary ischaemia, and abnormal expression of one HSP gene may cause hypertension in rats. We examined…”
Get full text

The effect of different mutations in the LDL receptor on plasma lipid concentrations and the age of onset of coronary artery disease in patients with familial hypercholestrolaemia (FH) by Gudnason, V., Whittall, R., Day, I.N.M., Soular, A.K., McCarthy, S.N., Day, L., Patterson, D., Seed, M., Thompson, G.R., Betteridge, J.D., Humphries, S.E.

Get full text

W14.345 Mutation scanning of LDLR in the whole population by Alharbi, K.K., Haddad, L., Ye, S., Lawlor, D.A., Whittall, R.A., Spanakis, E., Chen, X., Rassoulian, H., Simpson, I., Phillips, D.I.W., Cooper, C., Davey Smith, G., Humphries, S.E., Ebrahim, S., Day, I.N.M.

Get full text

Sequence conservation in the 3′-untranslated regions of neurone-specific enolase, lymphokine and protooncogene mRNAs by Day, I.N.M., Allsopp, M.T.E.P., Moore, D.C.McN, Thompson, R.J.

“…The C-terminal protein-coding and the entire 3′-untranslated regions of a cDNA corresponding to human neurone-specific enolase mRNA have been sequenced. The…”
Get full text

Localisation of neurone-specific enolase (ENO2) to 12p13 by Craig, S P, Day, I N, Thompson, R J, Craig, I W

“…We have localised the human cDNA for neurone-specific enolase (ENO2) to chromosome region 12p13 by in situ hybridisation. Two additional smaller peaks of…”
Get more information