Search Results - "Day, Emily S."

Gold nanoparticle‐mediated photothermal therapy: applications and opportunities for multimodal cancer treatment by Riley, Rachel S., Day, Emily S.

“…Photothermal therapy (PTT), in which nanoparticles embedded within tumors generate heat in response to exogenously applied laser light, has been well…”
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Elucidating the Fundamental Mechanisms of Cell Death Triggered by Photothermal Therapy by Melamed, Jilian R, Edelstein, Rachel S, Day, Emily S

“…Photothermal therapy (PTT) utilizes nanoparticles embedded within tumors as exogenous energy absorbers to convert laser light energy into heat to ablate cancer…”
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Spherical Nucleic Acid Nanoparticles: Therapeutic Potential by Kapadia, Chintan H., Melamed, Jilian R., Day, Emily S.

“…Spherical nucleic acids (SNAs) are highly oriented, well organized, polyvalent structures of nucleic acids conjugated to hollow or solid core nanoparticles…”
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A New Era for Cancer Treatment: Gold-Nanoparticle-Mediated Thermal Therapies by Kennedy, Laura C., Bickford, Lissett R., Lewinski, Nastassja A., Coughlin, Andrew J., Hu, Ying, Day, Emily S., West, Jennifer L., Drezek, Rebekah A.

“…Nanotechnology‐based cancer treatment approaches potentially provide localized, targeted therapies that aim to enhance efficacy, reduce side effects, and…”
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Dual Regulation of miR-34a and Notch Signaling in Triple-Negative Breast Cancer by Antibody/miRNA Nanocarriers by Valcourt, Danielle M., Day, Emily S.

“…Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer that lacks expression of the three most common receptors present on other…”
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Antibody-nanoparticle conjugates to enhance the sensitivity of ELISA-based detection methods by Billingsley, Margaret M, Riley, Rachel S, Day, Emily S

“…Accurate antigen detection is imperative for clinicians to diagnose disease, assess treatment success, and predict patient prognosis. The most common technique…”
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Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma by Jensen, Samuel A, Day, Emily S, Ko, Caroline H, Hurley, Lisa A, Luciano, Janina P, Kouri, Fotini M, Merkel, Timothy J, Luthi, Andrea J, Patel, Pinal C, Cutler, Joshua I, Daniel, Weston L, Scott, Alexander W, Rotz, Matthew W, Meade, Thomas J, Giljohann, David A, Mirkin, Chad A, Stegh, Alexander H

“…Glioblastoma multiforme (GBM) is a neurologically debilitating disease that culminates in death 14 to 16 months after diagnosis. An incomplete understanding of…”
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Nanoparticles for thermal cancer therapy by Day, Emily S, Morton, Jennifer G, West, Jennifer L

“…Advances in nanotechnology are enabling many new diagnostic and therapeutic approaches in cancer. In this review, examples where nanoparticles are employed to…”
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Gold Nanoshell-Linear Tetrapyrrole Conjugates for Near Infrared-Activated Dual Photodynamic and Photothermal Therapies by Wang, Jianxin, Potocny, Andrea M, Rosenthal, Joel, Day, Emily S

“…Photodynamic therapy (PDT) is a treatment in which photoactive compounds delivered to cancerous tissues are excited with light and then transfer the absorbed…”
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Cancer Cell Membrane Wrapped Nanoparticles for the Delivery of a Bcl‑2 Inhibitor to Triple-Negative Breast Cancer by Scully, Mackenzie A., Wilkins, Dana E., Dang, Megan N., Hoover, Elise C., Aboeleneen, Sara B., Day, Emily S.

“…Overexpression of the antiapoptotic protein B-cell lymphoma 2 (Bcl-2) is correlated with poor survival outcomes in triple-negative breast cancer (TNBC), making…”
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Introduction to Editorial Board Member: Professor Jennifer L. West by Day, Emily S.

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Combination cancer imaging and phototherapy mediated by membrane-wrapped nanoparticles by Aboeleneen, Sara B, Scully, Mackenzie A, Kramarenko, George C, Day, Emily S

“…Cancer is a devastating health problem with inadequate treatment options. Many conventional treatments for solid-tumor cancers lack tumor specificity, which…”
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Nanotechnologies for the detection and treatment of endometriosis by Sahni, Maneesha, Day, Emily S

“…Endometriosis is an incurable gynecologic disease characterized by endometrial-like tissue growth outside of the uterine cavity. It affects approximately 10%…”
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Spherical Nucleic Acid Architecture Can Improve the Efficacy of Polycation-Mediated siRNA Delivery by Melamed, Jilian R., Kreuzberger, Nicole L., Goyal, Ritu, Day, Emily S.

“…Clinical translation of small interfering RNA (siRNA) nanocarriers is hindered by limited knowledge regarding the parameters that regulate interactions between…”
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Nanoshell-mediated photothermal therapy improves survival in a murine glioma model by Day, Emily S., Thompson, Patrick A., Zhang, Linna, Lewinski, Nastassja A., Ahmed, Nabil, Drezek, Rebekah A., Blaney, Susan M., West, Jennifer L.

“…We are developing a novel treatment for high-grade gliomas using near infrared-absorbing silica–gold nanoshells that are thermally activated upon exposure to a…”
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Membrane-wrapped nanoparticles for photothermal cancer therapy by Aboeleneen, Sara B., Scully, Mackenzie A., Harris, Jenna C., Sterin, Eric H., Day, Emily S.

“…Cancer is a global health problem that needs effective treatment strategies. Conventional treatments for solid-tumor cancers are unsatisfactory because they…”
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Antibody-conjugated gold-gold sulfide nanoparticles as multifunctional agents for imaging and therapy of breast cancer by Day, Emily S, Bickford, Lissett R, Slater, John H, Riggall, Nicholas S, Drezek, Rebekah A, West, Jennifer L

“…The goal of this study was to develop near-infrared (NIR) resonant gold-gold sulfide nanoparticles (GGS-NPs) as dual contrast and therapeutic agents for cancer…”
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FZD7-Targeted Nanoparticles to Enhance Doxorubicin Treatment of Triple-Negative Breast Cancer by Hoover, Elise C., Ruggiero, Olivia M., Swingler, Rachel N., Day, Emily S.

“…Doxorubicin (DOX) is a chemotherapy agent commonly used to treat triple-negative breast cancer (TNBC), but it has insufficient efficacy against the disease and…”
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Biomimetic Nanoparticles for the Treatment of Hematologic Malignancies by Powsner, Emily H., Harris, Jenna C., Day, Emily S.

“…Hematologic malignancies are a prevalent group of cancers that originate from abnormal hematopoietic stem cells (HSCs) in the bone marrow. As these cells…”
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Megakaryocyte membrane‐wrapped nanoparticles for targeted cargo delivery to hematopoietic stem and progenitor cells by Das, Samik, Harris, Jenna C., Winter, Erica J., Kao, Chen‐Yuan, Day, Emily S., Papoutsakis, Eleftherios Terry

“…Hematopoietic stem and progenitor cells (HSPCs) are desirable targets for gene therapy but are notoriously difficult to target and transfect. Existing viral…”
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