Search Results - "Dawood, Reham M"

The Impact of COVID-19 on Liver Injury by Dawood, Dr. Reham M., Salum, Ghada Maher, El-Meguid, Mai Abd

“…The current coronavirus disease outbreak of 2019 (COVID-19) has led to a global pandemic. The principal cause of mortality in COVID-19 is represented lung…”
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A multiepitope peptide vaccine against HCV stimulates neutralizing humoral and persistent cellular responses in mice by Dawood, Reham M, Moustafa, Rehab I, Abdelhafez, Tawfeek H, El-Shenawy, Reem, El-Abd, Yasmine, Bader El Din, Noha G, Dubuisson, Jean, El Awady, Mostafa K

“…Although DAAs hold promise to significantly reduce rates of chronic HCV infections, its eradication still requires development of an effective vaccine…”
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Bioinformatics prediction of B and T cell epitopes within the spike and nucleocapsid proteins of SARS-CoV2 by Dawood, Reham M., El-Meguid, Mai A., Salum, Ghada M., El-Wakeel, Khaled, Shemis, Mohamed, El Awady, Mostafa K.

“…The striking difference in severity of SARS CoV2 infection among global population is partly attributed to viral factors. With the spike (S) and nucleocapsid…”
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Correlation between IL28B/TLR4 genetic variants and HCC development with/without DAAs treatment in chronic HCV patients by Salum, Ghada M., Dawood, Reham M., Abd el-Meguid, Mai, Ibrahim, Noha E., Abdel Aziz, Ashraf O., El Awady, Mostafa K.

“…In Egypt, Sofosbuvir (SOF) in combination with Dataclasvir (DCV) is the broadly used DAAs with excellent therapeutic profile. This study is designed to explore…”
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Recognition of 7 genes signature (Cirrhosis Risk Score) in the diagnosed non-responders to DAAs therapy by intra-PBMCs nested HCV RNA PCR by Galal, Al-Shazly Gaber Mohamed, Dawood, Reham M, Awady, Mostafa K. El, El-Dessouky, Yasser Mohamed Mohamed, Mahmoud, Mohamed Mahmoud Abdel-Halim, Alla, Mohamed Darwish Ahmed Abd

“…Background and aims Predictors of chronic HCV response to oral antiviral therapy (OAT) are related to host genetic variations. Single nucleotide polymorphisms…”
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Transcriptional Dysregulation of Upstream Signaling of IFN Pathway in Chronic HCV Type 4 Induced Liver Fibrosis by Ibrahim, Marwa K, Salum, Ghada Maher, Bader El Din, Noha G, Dawood, Reham M, Barakat, Ahmed, Khairy, Ahmed, El Awady, Mostafa K

“…IFN orchestrates the expression of various genes to halt hepatitis C virus (HCV) replication with the possibility of either reduced or increased liver…”
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Seven gene signature explores the impact of DAAs on the appearance of hepatocellular carcinoma in HCV infected patients by Dawood, Reham M., El-Meguid, Mai Abd, Shousha, Hend Ibrahim, Elsayed, Ahmed, Nabeel, Mohamed Mahmoud, Yosry, Ayman, Abdelaziz, Ashraf, Salum, Ghada M.

“…HCV damages the hepatocytes ending with hepatocellular carcinoma (HCC). The direct-acting antivirals (DAAs) treatment has raised hopes for reducing the…”
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Vascular Endothelial Growth Factor Expression in Hepatitis C Virus-Induced Liver Fibrosis: A Potential Biomarker by Salum, Ghada M, Bader El Din, Noha G, Ibrahim, Marwa K, Anany, Mohamed A, Dawood, Reham M, Khairy, Ahmed, El Awady, Mostafa K

“…The major complication of hepatitis C virus (HCV) infection is the induction of hepatic fibrosis. In this study, we investigated the correlation between the…”
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Tumor necrosis factor-α-G308A polymorphism is associated with liver pathological changes in hepatitis C virus patients by Bader El Din, Noha G, Farouk, Sally, El-Shenawy, Reem, Ibrahim, Marwa K, Dawood, Reham M, Elhady, Mostafa M, Salem, Ahmed M, Zayed, Naglaa, Khairy, Ahmed, El Awady, Mostafa K

“…AIM To investigate the association of tumor necrosis factor alpha(TNFα)-G308 A polymorphism with different liver pathological changes in treatment-na?ve…”
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HCV treatment outcome depends on SNPs of IFNL3-Gene polymorphisms (rs12979860) and cirrhotic changes in liver parenchyma by Abd Alla, Mohamed Darwish Ahmed, Dawood, Reham M., Rashed, Hassan Abd EL-Hafeth, El-Dessouky, Yasser Mohammed, AbuFarrag, Galal AbdElhameed, Ammar, Islam Abdelmawla Emran, Mahmoud, Mohamed Mahmoud Abdel-Halim, Salum, Ghada M., Abu-Amer, Mohamed Zakaria, Sekeen, Mohamed Abd elrafaa Hassan, Heggazy, Mohamed Mousa Ibraheem, Altanbouly, Ahmed Mohamed Abdulhamid, Abd El-Meguid, Mai, El Awady, Mostafa K.

“…The allelic discrimination of IFNL3-(rs12979860 C > T) polymorphism reveals ambiguous associations with the effectiveness of oral HCV treatment. Solitary intra…”
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Biochemical differences between nano- and normal formulation of tamoxifen and other natural bioactive materials ameliorate breast cancer in experimental rats by Ezzat, Afaf, Abdelhamid, Abdou Osman, El Awady, Mostafa K., Dawood, Reham M., Mohammed, Dina Mostafa

“…Background Human breast cancer is the most prevalent malignancy in women all-over the world. The aim is to look further into the effectiveness of the…”
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Expression of Reactive Oxygen Species-Related Transcripts in Egyptian Children With Autism by Meguid, Nagwa A, Ghozlan, Said A S, Mohamed, Magda F, Ibrahim, Marwa K, Dawood, Reham M, Bader El Din, Noha G, Abdelhafez, Tawfeek H, Hemimi, Maha, El Awady, Mostafa K

“…The molecular basis of the pathophysiological role of oxidative stress in autism is understudied. Herein, we used polymerase chain reaction (PCR) array to…”
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HCV Therapy Follow-up Fractionation (CTF2) by Intra-PBMC Nested RNA PCR Recognizes Early Virologic Response and Relapse by Abd Alla, Mohamed Darwish Ahmed, Elibiary, Saleh Ahmed, Elshaboury, Ramy Hassan, Wu, George Y, Dawood, Reham M, El Awady, Mostafa Kamel

“…Sustained virologic response is evaluated by single-step reverse transcription (SRT) PCR assay, which assesses hepatitis C virus (HCV) clearance from plasma…”
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Comprehensive assessment of circulatory miRNAs as potential diagnostic markers in HCV recurrence post liver transplantation by Salum, Ghada M., Abd El Meguid, Mai, Fotouh, Basma E., Abdel Aziz, Ashraf O., Dawood, Reham M.

“…HCV recurrence after liver transplantation is one of the causal agents for graft rejection. This study aims to profile non-invasive biomarkers in patients with…”
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Predictors of Disease Recurrence Post Living Donor Liver Transplantation in End Stage Chronic HCV Patients by Dawood, Reham M., Abdel Aziz, Ashraf O., El Awady, Mostafa K., Hunter, Shereen Shoukry, Elbaz, Tamer Mahmoud, Abdelhafez, Tawfeek H., Bader El Din, Noha G., Abdel Aziz Riad, Mahmoud, Omran, Moataza H.

“…HCV recurrence represents a universal phenomenon after liver transplantation. In this study Fifty HCV patients who underwent living donor liver transplantation…”
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Recipient interleukin 6 gene polymorphism and expression predict HCV recurrence post liver transplantation by Dawood, Reham M., Salum, Ghada M., Abd El-Meguid, Mai, Shemis, Mohamed, Abdel Aziz, Ashraf O., El Awady, Mostafa K.

“…•Host factors controlling post LTX recurrence probably mimic chronic HCV related cirrhosis.•High levels of IL-6 are linked with higher risk of Hepatocellular…”
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Evaluation of the expression of fibrosis-related genes as non-invasive diagnostic biomarkers for cirrhotic HCV-infected patients by El-Meguid, Mai Abd, Lotaif, Lotaif Mostafa, Salum, Ghada M., Fotouh, Basma E., Salama, Rabab Maamoun, Salem, Mohamed Ibrahim Seif Elnasr, El Awady, Mostafa K., Abdel Aziz, Ashraf Omar, Dawood, Reham M.

“…•Liver cirrhosis triggers architectural disruption and chronic inflammation.•Early detection of cirrhosis is mandatory to minimize the mortality risk.•TGFβ…”
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Bioactive glass doped with noble metal nanoparticles for bone regeneration: in vitro kinetics and proliferative impact on human bone cell line by Mostafa, Amany A, El-Sayed, Mayyada M H, Emam, Ahmed N, Abd-Rabou, Ahmed A, Dawood, Reham M, Oudadesse, Hassane

“…This work investigates the bioactivity of novel silver-doped (BG-Ag) and gold-doped (BG-Au) quaternary 46S6 bioactive glasses synthesized a semi-solid-state…”
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Polymorphism in Variable Number of Tandem Repeats of Dopamine D4 Gene Is a Genetic Risk Factor in Attention Deficit Hyperactive Egyptian Children: Pilot Study by Shahin, Ola, Meguid, Nagwa A., Raafat, Omnia, Dawood, Reham M., Doss, Malak, Din, Noha G. Bader El, Awady, Mostafa K. El

“…Introduction The variable number of tandem repeats (VNTR) of the dopamine receptor D4 (DRD4) gene among humans may elucidate individual differences in…”
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Development of a gene signature for predicting cirrhosis risk score of chronic liver disease associated with HCV infection in Egyptians by Dawood, Reham M., Salum, Ghada M., El-Meguid, Mai Abd, Elsayed, Ahmed, Yosry, Ayman, Abdelaziz, Ashraf, Shousha, Hend Ibrahim, Nabeel, Mohamed Mahmoud, El Awady, Mostafa K.

“…Complex diseases such as fibrosis are likely polygenic. Lately, cirrhosis risk score (CRS) clearly discriminated Chronic HCV patients with high-risk versus…”
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