Search Results - "Dawes, Timothy J.W"

Tranexamic Acid in Patients Undergoing Coronary-Artery Surgery by Jimenez-Rivera, Juan J, Iribarren-Sarrías, Jose L, Martínez-Sanz, Rafael, Wang, Dian-Shi, Mazer, C. David, Orser, Beverley A, Milojevic, Milan, Kappetein, A. Pieter, Head, Stuart J, Dawes, Timothy J.W, Price, Susanna, Myles, Paul S, Smith, Julian A, Painter, Thomas

“…To the Editor: Myles et al. (Jan. 12 issue) 1 found that the risk of death was not significantly higher with tranexamic acid than with placebo among patients…”
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Genetic and functional insights into the fractal structure of the heart by Meyer, Hannah V., Dawes, Timothy J. W., Serrani, Marta, Bai, Wenjia, Tokarczuk, Paweł, Cai, Jiashen, de Marvao, Antonio, Henry, Albert, Lumbers, R. Thomas, Gierten, Jakob, Thumberger, Thomas, Wittbrodt, Joachim, Ware, James S., Rueckert, Daniel, Matthews, Paul M., Prasad, Sanjay K., Costantino, Maria L., Cook, Stuart A., Birney, Ewan, O’Regan, Declan P.

“…The inner surfaces of the human heart are covered by a complex network of muscular strands that is thought to be a remnant of embryonic development 1 , 2 . The…”
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Reevaluating the Genetic Contribution of Monogenic Dilated Cardiomyopathy by Mazzarotto, Francesco, Tayal, Upasana, Buchan, Rachel J., Midwinter, William, Wilk, Alicja, Whiffin, Nicola, Govind, Risha, Mazaika, Erica, de Marvao, Antonio, Dawes, Timothy J.W., Felkin, Leanne E., Ahmad, Mian, Theotokis, Pantazis I., Edwards, Elizabeth, Ing, Alexander Y., Thomson, Kate L., Chan, Laura L.H., Sim, David, Baksi, A. John, Pantazis, Antonis, Roberts, Angharad M., Watkins, Hugh, Funke, Birgit, O’Regan, Declan P., Olivotto, Iacopo, Barton, Paul J.R., Prasad, Sanjay K., Cook, Stuart A., Ware, James S., Walsh, Roddy

“…BACKGROUND:Dilated cardiomyopathy (DCM) is genetically heterogeneous, with >100 purported disease genes tested in clinical laboratories. However, many genes…”
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Body Fat Is Associated With Reduced Aortic Stiffness Until Middle Age by Corden, Ben, Keenan, Niall G, de Marvao, Antonio S.M, Dawes, Timothy J.W, DeCesare, Alain, Diamond, Tamara, Durighel, Giuliana, Hughes, Alun D, Cook, Stuart A, O’Regan, Declan P

“…Obesity is a major risk factor for cardiometabolic disease, but the effect of body composition on vascular aging and arterial stiffness remains uncertain. We…”
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Precursors of Hypertensive Heart Phenotype Develop in Healthy Adults by de Marvao, Antonio, PhD, Dawes, Timothy J.W., PhD, Shi, Wenzhe, PhD, Durighel, Giuliana, MSc, Rueckert, Daniel, PhD, Cook, Stuart A., PhD, O’Regan, Declan P., PhD

“…Abstract Objectives This study used high-resolution 3-dimensional cardiac magnetic resonance to define the anatomical and functional left ventricular (LV)…”
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Automatic 3D Bi-Ventricular Segmentation of Cardiac Images by a Shape-Refined Multi- Task Deep Learning Approach by Duan, Jinming, Bello, Ghalib, Schlemper, Jo, Bai, Wenjia, Dawes, Timothy J. W., Biffi, Carlo, de Marvao, Antonio, Doumoud, Georgia, O'Regan, Declan P., Rueckert, Daniel

“…Deep learning approaches have achieved state-of-the-art performance in cardiac magnetic resonance (CMR) image segmentation. However, most approaches have…”
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A bi-ventricular cardiac atlas built from 1000+ high resolution MR images of healthy subjects and an analysis of shape and motion by Bai, Wenjia, Shi, Wenzhe, de Marvao, Antonio, Dawes, Timothy J.W., O’Regan, Declan P., Cook, Stuart A., Rueckert, Daniel

“…•Constructed a cardiac atlas from 1000+ MR images.•Images from a unique data set with high resolution and image consistency.•Shape, motion and wall thickness…”
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Artificial intelligence and the cardiologist: what you need to know for 2020 by de Marvao, Antonio, Dawes, Timothy Jw, Howard, James Philip, O'Regan, Declan P

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Phenotypic Expression and Outcomes in Individuals With Rare Genetic Variants of Hypertrophic Cardiomyopathy by de Marvao, Antonio, McGurk, Kathryn A, Zheng, Sean L, Thanaj, Marjola, Bai, Wenjia, Duan, Jinming, Biffi, Carlo, Mazzarotto, Francesco, Statton, Ben, Dawes, Timothy J W, Savioli, Nicolò, Halliday, Brian P, Xu, Xiao, Buchan, Rachel J, Baksi, A John, Quinlan, Marina, Tokarczuk, Paweł, Tayal, Upasana, Francis, Catherine, Whiffin, Nicola, Theotokis, Pantazis I, Zhang, Xiaolei, Jang, Mikyung, Berry, Alaine, Pantazis, Antonis, Barton, Paul J R, Rueckert, Daniel, Prasad, Sanjay K, Walsh, Roddy, Ho, Carolyn Y, Cook, Stuart A, Ware, James S, O'Regan, Declan P

“…Hypertrophic cardiomyopathy (HCM) is caused by rare variants in sarcomere-encoding genes, but little is known about the clinical significance of these variants…”
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Predicting Peri-Operative Cardiorespiratory Adverse Events in Children with Idiopathic Pulmonary Arterial Hypertension Undergoing Cardiac Catheterization Using Echocardiography: A Cohort Study by Dawes, Timothy J W, Woodham, Valentine, Sharkey, Emma, McEwan, Angus, Derrick, Graham, Muthurangu, Vivek, Moledina, Shahin, Hepburn, Lucy

“…General anesthesia in children with idiopathic pulmonary arterial hypertension (PAH) carries an increased risk of peri-operative cardiorespiratory…”
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Deep-learning cardiac motion analysis for human survival prediction by Bello, Ghalib A., Dawes, Timothy J. W., Duan, Jinming, Biffi, Carlo, de Marvao, Antonio, Howard, Luke S. G. E., Gibbs, J. Simon R., Wilkins, Martin R., Cook, Stuart A., Rueckert, Daniel, O’Regan, Declan P.

“…Motion analysis is used in computer vision to understand the behaviour of moving objects in sequences of images. Optimizing the interpretation of dynamic…”
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Phosphodiesterase 5 inhibitor treatment and survival in interstitial lung disease pulmonary hypertension: A Bayesian retrospective observational cohort study by Dawes, Timothy J. W., McCabe, Colm, Dimopoulos, Konstantinos, Stewart, Iain, Bax, Simon, Harries, Carl, Samaranayake, Chinthaka B., Kempny, Aleksander, Molyneaux, Philip L., Seitler, Samuel, Semple, Thomas, Li, Wei, George, Peter M., Kouranos, Vasileios, Chua, Felix, Renzoni, Elisabetta A., Kokosi, Maria, Jenkins, Gisli, Wells, Athol U., Wort, Stephen J., Price, Laura C.

“…Background and Objective Pulmonary hypertension is a life‐limiting complication of interstitial lung disease (ILD‐PH). We investigated whether treatment with…”
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Three-dimensional cardiovascular imaging-genetics: a mass univariate framework by Biffi, Carlo, de Marvao, Antonio, Attard, Mark I, Dawes, Timothy J W, Whiffin, Nicola, Bai, Wenjia, Shi, Wenzhe, Francis, Catherine, Meyer, Hannah, Buchan, Rachel, Cook, Stuart A, Rueckert, Daniel, O'Regan, Declan P

“…Abstract Motivation Left ventricular (LV) hypertrophy is a strong predictor of cardiovascular outcomes, but its genetic regulation remains largely unexplained…”
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Moderate Physical Activity in Healthy Adults Is Associated With Cardiac Remodeling by Dawes, Timothy J W, Corden, Ben, Cotter, Sorcha, de Marvao, Antonio, Walsh, Roddy, Ware, James S, Cook, Stuart A, O'Regan, Declan P

“…Cardiac mass and volumes are often elevated in athletes, but it is not known whether moderate physical activity is also associated with cardiac dilatation and…”
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Precursors of Hypertensive Heart Phenotype Develop in Healthy Adults: A High-Resolution 3D MRI Study by de Marvao, Antonio, Dawes, Timothy J W, Shi, Wenzhe, Durighel, Giuliana, Rueckert, Daniel, Cook, Stuart A, O'Regan, Declan P

“…This study used high-resolution 3-dimensional cardiac magnetic resonance to define the anatomical and functional left ventricular (LV) properties associated…”
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Fractal Analysis of Right Ventricular Trabeculae in Pulmonary Hypertension by Dawes, Timothy J W, Cai, Jiashen, Quinlan, Marina, de Marvao, Antonio, Ostrowski, Philip J, Tokarczuk, Paweł F, Watson, Geoffrey M J, Wharton, John, Howard, Luke S G E, Gibbs, J Simon R, Cook, Stuart A, Wilkins, Martin R, O'Regan, Declan P

“…Purpose To measure right ventricular (RV) trabecular complexity by its fractal dimension (FD) in healthy subjects and patients with pulmonary hypertension (PH)…”
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Metabolic pathways associated with right ventricular adaptation to pulmonary hypertension: 3D analysis of cardiac magnetic resonance imaging by Attard, Mark I, Dawes, Timothy J W, de Marvao, Antonio, Biffi, Carlo, Shi, Wenzhe, Wharton, John, Rhodes, Christopher J, Ghataorhe, Pavandeep, Gibbs, J Simon R, Howard, Luke S G E, Rueckert, Daniel, Wilkins, Martin R, O'Regan, Declan P

“…We sought to identify metabolic pathways associated with right ventricular (RV) adaptation to pulmonary hypertension (PH). We evaluated candidate metabolites,…”
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Sex and regional differences in myocardial plasticity in aortic stenosis are revealed by 3D model machine learning by Bhuva, Anish N, Treibel, Thomas A, De Marvao, Antonio, Biffi, Carlo, Dawes, Timothy J W, Doumou, Georgia, Bai, Wenjia, Patel, Kush, Boubertakh, Redha, Rueckert, Daniel, O’Regan, Declan P, Hughes, Alun D, Moon, James C, Manisty, Charlotte H

“…Abstract Aims Left ventricular hypertrophy (LVH) in aortic stenosis (AS) varies widely before and after aortic valve replacement (AVR), and deeper phenotyping…”
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Artificial Intelligence for Cardiac Imaging-Genetics Research by de Marvao, Antonio, Dawes, Timothy J W, O'Regan, Declan P

“…Cardiovascular conditions remain the leading cause of mortality and morbidity worldwide, with genotype being a significant influence on disease risk. Cardiac…”
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