Search Results - "Dawe, J."
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Physical activity, common brain pathologies, and cognition in community-dwelling older adults
Published in Neurology (19-02-2019)“…OBJECTIVETo examine the associations of physical activity, Alzheimer disease (AD), and other brain pathologies and cognition in older adults. METHODSWe studied…”
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Inferring protein expression changes from mRNA in Alzheimer’s dementia using deep neural networks
Published in Nature communications (03-02-2022)“…Identifying the molecular systems and proteins that modify the progression of Alzheimer’s disease and related dementias (ADRD) is central to drug target…”
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3
Statistical analysis of an LES shallow cumulus cloud ensemble using a cloud tracking algorithm
Published in Atmospheric chemistry and physics (26-01-2012)“…A technique for the tracking of individual clouds in a Large Eddy Simulation (LES) is presented. We use this technique on an LES of a shallow cumulus cloud…”
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Contribution of TDP and hippocampal sclerosis to hippocampal volume loss in older-old persons
Published in Neurology (14-01-2020)“…OBJECTIVETo investigate the contribution of Alzheimer disease (AD) vs non-AD neuropathologies to hippocampal atrophy. METHODSThe Religious Orders Study and…”
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Direct entrainment and detrainment rate distributions of individual shallow cumulus clouds in an LES
Published in Atmospheric chemistry and physics (13-08-2013)“…Probability distribution functions of shallow cumulus cloud core entrainment and detrainment rates are calculated using 4362 individual cumulus clouds isolated…”
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Neuropathologic correlates of hippocampal atrophy in the elderly: a clinical, pathologic, postmortem MRI study
Published in PloS one (17-10-2011)“…The volume of the hippocampus measured with structural magnetic resonance imaging (MRI) is increasingly used as a biomarker for Alzheimer's disease (AD)…”
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Motor function is the primary driver of the associations of sarcopenia and physical frailty with adverse health outcomes in community-dwelling older adults
Published in PloS one (02-02-2021)“…This study tested the hypothesis that sarcopenia and its constituent components, reduced lean muscle mass and impaired motor function, are associated with…”
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Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data
Published in PLoS medicine (25-04-2017)“…The molecular underpinnings of the dissociation of cognitive performance and neuropathological burden are poorly understood, and there are currently no known…”
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Early mathematical models of COVID-19 vaccination in high-income countries: a systematic review
Published in Public health (London) (01-11-2024)“…Since COVID-19 first emerged in 2019, mathematical models have been developed to predict transmission and provide insight into disease control strategies. A…”
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Association Between Quantitative Gait and Balance Measures and Total Daily Physical Activity in Community-Dwelling Older Adults
Published in The journals of gerontology. Series A, Biological sciences and medical sciences (17-04-2018)“…Total daily physical activity is associated with a wide range of adverse health outcomes. We examined the extent to which quantitative measures of gait and…”
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Total daily physical activity, brain pathologies, and parkinsonism in older adults
Published in PloS one (29-04-2020)“…We examined the association of physical activity, postmortem brain pathologies, and parkinsonism proximate to death in older adults. We studied the brains of…”
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Dividing attention during the Timed Up and Go enhances associations of several subtask performances with MCI and cognition
Published in PloS one (03-08-2022)“…We tested the hypothesis that dividing attention would strengthen the ability to detect mild cognitive impairment (MCI) and specific cognitive abilities from…”
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Postmortem MRI of human brain hemispheres: T2 relaxation times during formaldehyde fixation
Published in Magnetic resonance in medicine (01-04-2009)“…Unlike in vivo imaging, postmortem MRI allows for invasive examination of the tissue specimen immediately after the MR scan. However, natural tissue…”
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Physical activity, brain tissue microstructure, and cognition in older adults
Published in PloS one (07-07-2021)“…To test whether postmortem MRI captures brain tissue characteristics that mediate the association between physical activity and cognition in older adults…”
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15
Financial incentives to increase engagement across the hepatitis C care cascade among people at risk of or diagnosed with hepatitis C: A systematic review
Published in The International journal of drug policy (01-11-2024)“…•Evidence for effectiveness of incentives to promote HCV care outcomes.•No randomised controlled trial assessed effectiveness of incentives for HCV…”
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Newborn screening for spinal muscular atrophy: The Wisconsin first year experience
Published in Neuromuscular disorders : NMD (01-02-2022)“…•SMA newborn screening via homozygous SMN1 exon 7 deletion without carrier identified.•Cost of SMA screening minimized by multiplexing with another screened…”
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Volumetric brain correlates of gait associated with cognitive decline in community-dwelling older adults
Published in Frontiers in aging neuroscience (04-10-2023)“…To determine the extent to which the regional brain volumes associated with slow gait speed can inform subsequent cognitive decline in older adults from the…”
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Expanding instrumented gait testing in the community setting: A portable, depth-sensing camera captures joint motion in older adults
Published in PloS one (15-05-2019)“…Currently, it is not feasible to obtain laboratory-based measures of joint motion in large numbers of older adults. We assessed the utility of a portable…”
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Ex-vivo quantitative susceptibility mapping of human brain hemispheres
Published in PloS one (20-12-2017)“…Ex-vivo brain quantitative susceptibility mapping (QSM) allows investigation of brain characteristics at essentially the same point in time as histopathologic…”
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Ankle arthroscopy to manage sequelae after ankle fractures
Published in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA (01-11-2015)“…Purpose The role of ankle arthroscopy in managing the consequences of ankle fractures is yet to be fully established. This study aims to assess this procedure…”
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