Search Results - "Dawe, David"

Treatment and Prevention of Brain Metastases in Small Cell Lung Cancer by Rittberg, Rebekah, Banerji, Shantanu, Kim, Julian O., Rathod, Shrinivas, Dawe, David E.

“…Central nervous system (CNS) metastasis will develop in 50% of small cell lung cancer (SCLC) patients throughout disease course. Development of CNS metastasis…”
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Pembrolizumab plus chemotherapy versus chemotherapy in untreated advanced pleural mesothelioma in Canada, Italy, and France: a phase 3, open-label, randomised controlled trial by Chu, Quincy, Perrone, Francesco, Greillier, Laurent, Tu, Wei, Piccirillo, Maria Carmela, Grosso, Federica, Lo Russo, Giuseppe, Florescu, Marie, Mencoboni, Manlio, Morabito, Alessandro, Cecere, Fabiana Letizia, Ceresoli, Giovanni Luca, Dawe, David E, Zucali, Paolo Andrea, Pagano, Maria, Goffin, John R, Sanchez, Myriam Locatelli, Gridelli, Cesare, Zalcman, Gerard, Quantin, Xavier, Westeel, Virginie, Gargiulo, Piera, Delfanti, Sara, Tu, Dongsheng, Lee, Christopher W, Leighl, Natasha, Sederias, Joana, Brown-Walker, Pamela, Luo, Yiwen, Lantuejoul, Sylvie, Tsao, Ming-Sound, Scherpereel, Arnaud, Bradbury, Penelope, Laurie, Scott A, Seymour, Lesley

“…Pleural mesothelioma usually presents at an advanced, incurable stage. Chemotherapy with platinum-pemetrexed is a standard treatment. We hypothesised that the…”
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Rice yields in tropical/subtropical Asia exhibit large but opposing sensitivities to minimum and maximum temperatures by Welch, Jarrod R., Vincent, Jeffrey R., Auffhammer, Maximilian, Moya, Piedad F., Dobermann, Achim, Dawe, David, Khush, Gurdev S.

“…Data from farmer-managed fields have not been used previously to disentangle the impacts of daily minimum and maximum temperatures and solar radiation on rice…”
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Immunotherapy in Patients with Advanced Non-Small-Cell Lung Cancer Under-Represented by Clinical Trials by Meyers, Daniel E, Rittberg, Rebekah, Dawe, David E, Banerji, Shantanu

“…Since the initial US FDA approval of an immune checkpoint inhibitor (ICI) for the treatment of non-oncogene-driven non-small-cell lung cancer (NSCLC) nine…”
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Effect of Hospitalization During First Chemotherapy and Performance Status on Small-cell Lung Cancer Outcomes by Rittberg, Rebekah, Green, Susan, Aquin, Trevor, Bucher, Oliver, Banerji, Shantanu, Dawe, David E.

“…Small-cell lung cancer (SCLC) is highly responsive to chemotherapy (CT) and one of the few malignancies treated in hospitalized patients with poor Eastern…”
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The Role of Immunotherapy in the Treatment of Malignant Pleural Mesothelioma by Banerji, Shantanu, Meyers, Daniel E, Harlos, Craig, Dawe, David E

“…Malignant pleural mesothelioma is a rare and aggressive malignancy arising from mesothelial cells that line the serous membranes of the body. Cytotoxic…”
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Immune Signatures of Non-Small Cell Lung Cancer by Green, Susan, Dawe, David E, Banerji, Shantanu

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Stage IV breast, colorectal, and lung cancer at diagnosis in adults living with intellectual or developmental disabilities: A population‐based cross‐sectional study by Mahar, Alyson L., Biggs, Kelly, Hansford, Rebecca L., Derksen, Shelley, Griffiths, Rebecca, Enns, Jennifer E., Dawe, David E., Hallet, Julie, Kristjanson, Mark, Decker, Kathleen, Cobigo, Virginie, Shooshtari, Shahin, Stirling, Morgan, Kelly, Christine, Brownell, Marni, Turner, Donna, Ouellette‐Kuntz, Hélène

“…Background Cancer is a leading cause of death among people living with intellectual or developmental disabilities (IDD). Although studies have documented lower…”
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The impact of the modified frailty index on clinical outcomes for patients with stage IV non-small cell lung cancer receiving chemotherapy by Mathur, Shivani, Prince, Laura, Bucher, Oliver, Xue, Lin, Banerji, Shantanu, Dawe, David E.

“…Frailty impacts outcomes for patients with lung cancer, but no brief tools have been assessed in patients with metastatic disease. We evaluated the impact of…”
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Treatment Patterns, Toxicity, and Outcomes of Older Adults With Advanced Pancreatic Cancer Receiving First-line Palliative Chemotherapy by McAndrew, Erin N., Zhang, Hanbo, Lambert, Pascal, Rittberg, Rebekah, Dawe, David E., Kim, Christina A.

“…Advanced pancreatic cancer (APC) disproportionately impacts older adults. Randomized trials demonstrate improved overall survival (OS) with combination…”
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The effect of statin use on the incidence of prostate cancer: A population‐based nested case–control study by Dawe, David E., Ye, Xibiao, Czaykowski, Piotr, Jassal, Davinder, Singh, Harminder, Skarsgard, David, Aprikian, Armen, Mahmud, Salaheddin M

“…Preclinical studies suggest statins may help prevent prostate cancer (PC), but epidemiologic results are mixed. Many epidemiological studies have relatively…”
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Real world risk of infusion reactions and effectiveness of front-line obinutuzumab plus chlorambucil compared with other frontline treatments for chronic lymphocytic leukemia by Bourrier, Nicole, Landego, Ivan, Bucher, Oliver, Squires, Mandy, Streu, Erin, Hibbert, Irena, Whiteside, Theresa, Gibson, Spencer B, Geirnaert, Marc, Johnston, James B, Dawe, David E, Banerji, Versha

“…Chronic lymphocytic leukemia (CLL) is the most common type of leukemia in North America. Previous studies have shown improved progression free survival (PFS)…”
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Breast (female), colorectal, and lung cancer survival in people with intellectual or developmental disabilities: A population-based retrospective cohort study by Hansford, Rebecca L., Ouellette-Kuntz, Hélène, Griffiths, Rebecca, Hallet, Julie, Decker, Kathleen, Dawe, David E., Kristjanson, Mark, Cobigo, Virginie, Shooshtari, Shahin, Stirling, Morgan, Kelly, Christine, Brownell, Marni, Turner, Donna, Mahar, Alyson

“…Objectives Cancer is a leading cause of death among people living with intellectual or developmental disabilities (IDD). There is little empirical evidence…”
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Real-world predictors of survival in patients with limited-stage small-cell lung cancer in Manitoba, Canada by Dawe, David E, Rittberg, Rebekah, Syed, Iqra, Shanahan, Mary Kate, Moldaver, Daniel, Bucher, Oliver, Galloway, Katie, Reynolds, Kayla, Paul, James T, Harlos, Craig, Kim, Julian O, Banerji, Shantanu

“…Although therapy for limited-stage small-cell lung cancer (LS-SCLC) is administered with curative intent, most patients relapse and eventually die of recurrent…”
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Real-world predictors of survival in patients with extensive-stage small-cell lung cancer in Manitoba, Canada: a retrospective cohort study by Dawe, David E, Rittberg, Rebekah, Syed, Iqra, Shanahan, Mary Kate, Moldaver, Daniel, Bucher, Oliver, Galloway, Katie, Reynolds, Kayla, Paul, James T, Harlos, Craig, Kim, Julian O, Banerji, Shantanu

“…Extensive-stage small-cell lung cancer (ES-SCLC) is an incurable cancer with poor prognosis in which characteristics predictive of long-term survival are…”
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Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions by Hajj-Boutros, Guy, Faust, Andréa, Muscedere, John, Kim, Perry, Abumrad, Naji, Chevalier, Stéphanie, Aubertin-Leheudre, Mylene, Bergman, Howard, Bowdish, Dawn, Burford, Jessica, Carrington-Lawrence, Stacy, Côté, Hélène, Dawe, David E, Barreto, Philipe de Souto, Farrelly, Colin, Fowler, Robert, Gouspillou, Gilles, Harrington, Lea, Lautrup, Sofie, Howlett, Susan, Imani, Mahdi, Kirkland, James, Kuchel, George, Mallette, Frédérick A, Morais, José A, Newman, John C, Pullman, Daryl, Sierra, Felipe, Van Raamsdonk, Jeremy, Watt, Jennifer, Rylett, Rebecca Jane, Duque, Gustavo

“…The inaugural Canadian Conferences on Translational Geroscience were held as 2 complementary sessions in October and November 2023. The conferences explored…”
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Chemoradiotherapy versus radiotherapy alone in elderly patients with stage III non-small cell lung cancer: a systematic review and meta-analysis by Dawe, David E, Christiansen, David, Swaminath, Anand, Ellis, Peter M, Rothney, Janet, Rabbani, Rasheda, Abou-Setta, Ahmed M, Zarychanski, Ryan, Mahmud, Salaheddin M

“…Highlights • Elderly (≥70 years) stage III NSCLC patients are often excluded from standard CRT. • Our meta-analysis shows CRT is superior to RT (HR 0.66) in…”
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Brief Report: Canadian Cancer Trials Group IND.227: A Phase 2 Randomized Study of Pembrolizumab in Patients With Advanced Malignant Pleural Mesothelioma (NCT02784171) by Piccirillo, Maria Carmela, Chu, Quincy, Bradbury, Penelope, Tu, Wei, Coschi, Courtney H, Grosso, Federica, Florescu, Marie, Mencoboni, Manlio, Goffin, John R, Pagano, Maria, Ciardiello, Fortunato, Cecere, Fabiana Letizia, Vincent, Mark, Ferrara, Roberto, Dawe, David E, Hao, Desiree, Lee, Christopher W, Morabito, Alessandro, Gridelli, Cesare, Cavanna, Luigi, Iqbal, Mussawar, Blais, Normand, Leighl, Natasha B, Wheatley-Price, Paul, Tsao, Ming-Sound, Ugo, Francesca, El-Osta, Hazem, Gargiulo, Piera, Gaudreau, Pierre-Olivier, Tu, Dongsheng, Sederias, Joana, Brown-Walker, Pamela, Perrone, Francesco, Seymour, Lesley, Laurie, Scott A

“…Immune checkpoint inhibitors have activity in mesothelioma. IND.227 was a phase 2 trial (120 patients planned) comparing progression-free survival of standard…”
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Impact of age, comorbidity, and polypharmacy on receipt of systemic therapy in advanced cancers: A retrospective population-based study by Rittberg, Rebekah, Decker, Kathleen, Lambert, Pascal, Bravo, Jen, St. John, Philip, Turner, Donna, Czaykowski, Piotr, Dawe, David E.

“…Cancer incidence, comorbidity, and polypharmacy increase with age, but the interplay between these factors on receipt of systemic therapy (ST) in advanced…”
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Biologic and epidemiologic evidence assessing if statins prevent prostate cancer by Dawe, David E, Mahmud, Salaheddin

“…During their lives, 1 in 8 men will be diagnosed with prostate cancer. Several drugs have been shown to decrease prostate cancer risk, but have not been widely…”
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