Search Results - "Davyt, Marcos"
-
1
Translation velocity determines the efficacy of engineered suppressor tRNAs on pathogenic nonsense mutations
Published in Nature communications (05-04-2024)“…Nonsense mutations – the underlying cause of approximately 11% of all genetic diseases – prematurely terminate protein synthesis by mutating a sense codon to a…”
Get full text
Journal Article -
2
On the Track of the Missing tRNA Genes: A Source of Non-Canonical Functions?
Published in Frontiers in molecular biosciences (16-03-2021)“…Cellular tRNAs appear today as a diverse population of informative macromolecules with conserved general elements ensuring essential common functions and…”
Get full text
Journal Article -
3
Teaching during the COVID-19 Pandemic: Sharing Results and Data Obtained from the Ames Test
Published in Journal of microbiology & biology education (01-12-2021)“…We present a resource for instructors that contains results and data sets from the Ames test. Our aim is to share the results we have collected in previous…”
Get full text
Journal Article -
4
Fine-tuning the metabolic rewiring and adaptation of translational machinery during an epithelial-mesenchymal transition in breast cancer cells
Published in Cancer & metabolism (19-07-2020)“…During breast cancer progression, the epithelial to mesenchymal transition has been associated with metastasis and endocrine therapy resistance; however, the…”
Get full text
Journal Article -
5
Effect of mRNA/tRNA mutations on translation speed: Implications for human diseases
Published in The Journal of biological chemistry (01-09-2023)“…Recent discoveries establish tRNAs as central regulators of mRNA translation dynamics, and therefore cotranslational folding and function of the encoded…”
Get full text
Journal Article -
6
Engineered tRNAs suppress nonsense mutations in cells and in vivo
Published in Nature (London) (22-06-2023)“…Nonsense mutations are the underlying cause of approximately 11% of all inherited genetic diseases 1 . Nonsense mutations convert a sense codon that is decoded…”
Get full text
Journal Article -
7
Ready to migrate? Reading cellular signs of migration in an epithelial to mesenchymal transition model
Published in Biocell (2022)“…The epithelial to mesenchymal transition (EMT) is a cellular program that drives de-differentiation of cells in both physiological and pathological processes…”
Get full text
Journal Article