Search Results - "Davydova, Tatiana V."

Intranasally Administered S100A9 Amyloids Induced Cellular Stress, Amyloid Seeding, and Behavioral Impairment in Aged Mice by Iashchishyn, Igor A, Gruden, Marina A, Moskalenko, Roman A, Davydova, Tatiana V, Wang, Chao, Sewell, Robert D. E, Morozova-Roche, Ludmilla A

“…Amyloid formation and neuroinflammation are major features of Alzheimer’s disease pathology. Proinflammatory mediator S100A9 was shown to act as a link between…”
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S100A9 Protein Aggregates Boost Hippocampal Glutamate Modifying Monoaminergic Neurochemistry: A Glutamate Antibody Sensitive Outcome on Alzheimer-like Memory Decline by Gruden, Marina A, Davydova, Tatiana V, Kudrin, Vladimir S, Wang, Chao, Narkevich, Victor B, Morozova-Roche, Ludmilla A, Sewell, Robert D. E

“…Alzheimer’s disease (AD) involves dementia conceivably arising from integrated inflammatory processes, amyloidogenesis, and neuronal apoptosis. Glutamate can…”
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The misfolded pro-inflammatory protein S100A9 disrupts memory via neurochemical remodelling instigating an Alzheimer’s disease-like cognitive deficit by Gruden, Marina A., Davydova, Tatiana V., Wang, Chao, Narkevich, Victor B., Fomina, Valentina G., Kudrin, Vladimir S., Morozova-Roche, Ludmilla A., Sewell, Robert D.E.

“…•Protein S100A9 oligomers and/or fibrils were given intranasally for 14 days in mice.•S100A9 oligomers and fibrils but not their mixture evoked passive…”
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Intranasal administration of alpha-synuclein aggregates: a Parkinson's disease model with behavioral and neurochemical correlates by Gruden, Marina A., Davydova, Tatiana V., Narkevich, Victor B., Fomina, Valentina G., Wang, Chao, Kudrin, Vladimir S., Morozova-Roche, Ludmilla A., Sewell, Robert D.E.

“…•α-Synuclein fibrils and/or oligomers were given intranasally for 14 days in mice.•Combined oligomers+fibrils caused rigidity and locomotor impairment.•Nigral…”
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Noradrenergic and serotonergic neurochemistry arising from intranasal inoculation with α-synuclein aggregates which incite parkinsonian-like symptoms by Gruden, Marina A., Davydova, Tatiana V., Narkevich, Victor B., Fomina, Valentina G., Wang, Chao, Kudrin, Vladimir S., Morozova-Roche, Ludmilla A., Sewell, Robert D.E.

“…•α-Synuclein fibrils and/or oligomers were given intranasally for 14 days in mice.•Combined oligomers+fibrils caused rigidity and locomotor impairment.•α-Syn…”
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