Search Results - "Davoodpour, Padideh"
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Interconnections between apoptotic, autophagic and necrotic pathways: implications for cancer therapy development
Published in Journal of cellular and molecular medicine (01-01-2013)“…Summary The rapid accumulation of knowledge on apoptosis regulation in the 1990s was followed by the development of several experimental anticancer‐ and…”
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2
Hepatic ACAT2 knock down increases ABCA1 and modifies HDL metabolism in mice
Published in PloS one (01-04-2014)“…ACAT2 is the exclusive cholesterol-esterifying enzyme in hepatocytes and enterocytes. Hepatic ABCA1 transfers unesterified cholesterol (UC) to apoAI, thus…”
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3
TiO 2 nanoparticles tested in a novel screening whole human blood model of toxicity trigger adverse activation of the kallikrein system at low concentrations
Published in Biomaterials (01-05-2015)“…There is a compelling need to understand and assess the toxicity of industrially produced nanoparticles (NPs). In order to appreciate the long-term effects of…”
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4
The thyroid receptor modulator KB3495 reduces atherosclerosis independently of total cholesterol in the circulation in ApoE deficient mice
Published in PloS one (04-12-2013)“…Thyroid hormones (TH) regulate cholesterol metabolism but their use as lipid-lowering drugs is restricted due to negative cardiac effects. TH mimetic compounds…”
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5
TGFβ1-Induced Activation of ATM and p53 Mediates Apoptosis in a Smad7-Dependent Manner
Published in Cell cycle (Georgetown, Tex.) (01-12-2006)“…ATM, a DNA-damage sensitive kinase and p53, are frequently inactivated in a variety of cancers as they together with γH2AX are critical guardians against DNA…”
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6
2-Methoxyestradiol-induced Apoptosis in Prostate Cancer Cells Requires Smad7
Published in The Journal of biological chemistry (15-04-2005)“…Prostate cancer is the second most common cause of death related to cancer in Western society. 2-Methoxyestradiol (2-ME), an endogenous metabolite of…”
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7
Reduced tumor growth in vivo and increased c-Abl activity in PC3 prostate cancer cells overexpressing the Shb adapter protein
Published in BMC cancer (15-08-2007)“…Induction of apoptosis is one strategy for treatment of prostate cancer. The Shb adapter protein has been found to regulate apoptosis in various cell types and…”
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8
TiO2 nanoparticles tested in a novel screening whole human blood model of toxicity trigger adverse activation of the kallikrein system at low concentrations
Published in Biomaterials (01-05-2015)“…Abstract There is a compelling need to understand and assess the toxicity of industrially produced nanoparticles (NPs). In order to appreciate the long-term…”
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Journal Article -
9
Contact (kallikrein/kinin) system activation in whole human blood induced by low concentrations of α-Fe2O3 nanoparticles
Published in Nanomedicine (01-04-2018)“…Iron-oxide nanoparticles (NPs) generated by environmental events are likely to represent health problems. α-Fe2O3 NPs were synthesized, characterized and…”
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10
Contact (kallikrein/kinin) system activation in whole human blood induced by low concentrations of α-Fe 2 O 3 nanoparticles
Published in Nanomedicine (01-04-2018)“…Iron-oxide nanoparticles (NPs) generated by environmental events are likely to represent health problems. α-Fe O NPs were synthesized, characterized and tested…”
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11
An overview of Brevinin superfamily: structure, function and clinical perspectives
Published in Advances in experimental medicine and biology (01-01-2014)“…Antimicrobial peptides are the backbone of first-line defense against various microorganisms in the animal kingdom. Thus, not surprisingly, they are gaining…”
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12
Virus-triggered autophagy in viral hepatitis - possible novel strategies for drug development
Published in Journal of viral hepatitis (01-12-2011)“…Autophagy is a very tightly regulated process that is important in many cellular processes including development, differentiation, survival and homoeostasis…”
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13
TGF beta 1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner
Published in Cell cycle (Georgetown, Tex.) (01-12-2006)“…ATM, a DNA-damage sensitive kinase and p53, are frequently inactivated in a variety of cancers as they together with gamma H2AX are critical guardians against…”
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Journal Article -
14
Hepatic ACAT2 Knock Down Increases ABCA1 and Modifies HDL Metabolism in Mice: e93552
Published in PloS one (01-04-2014)“…Objectives ACAT2 is the exclusive cholesterol-esterifying enzyme in hepatocytes and enterocytes. Hepatic ABCA1 transfers unesterified cholesterol (UC) to…”
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15
Effects of 2-ME on proliferation, apoptosis and PET-tracer uptake in human prostate cancer cell aggregates
Published in Nuclear medicine and biology (2004)Get full text
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Effects of 2-methoxyestradiol on proliferation, apoptosis and PET-tracer uptake in human prostate cancer cell aggregates
Published in Nuclear medicine and biology (01-10-2004)“…The purpose of this study was to investigate the potential use of PET in vivo to record cytotoxic effects of 2-methoxyestradiol (2-ME), an endogenous…”
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17
Synthesis and biological evaluation of novel carbon-11-labelled analogues of citalopram as potential radioligands for the serotonin transporter
Published in Bioorganic & medicinal chemistry (05-08-2003)“…Three serotonin reuptake inhibitors where the 5-cyano group in citalopram…”
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18
TGFbeta1-induced activation of ATM and p53 mediates apoptosis in a Smad7-dependent manner
Published in Cell cycle (Georgetown, Tex.) (01-12-2006)“…ATM, a DNA-damage sensitive kinase and p53, are frequently inactivated in a variety of cancers as they together with gammaH2AX are critical guardians against…”
Get full text
Journal Article