Search Results - "Davis Jones, Gabriel"
-
1
An Investigation of Levetiracetam in Alzheimer's Disease (ILiAD): a double-blind, placebo-controlled, randomised crossover proof of concept study
Published in Current controlled trials in cardiovascular medicine (31-07-2021)“…Although Alzheimer's disease affects around 800,000 people in the UK and costs almost £23 billion per year, currently licenced treatments only offer modest…”
Get full text
Journal Article -
2
Protective effects of medium chain triglyceride diet in a mouse model of Dravet syndrome
Published in Epilepsia (Copenhagen) (01-12-2021)“…Objective Dravet syndrome (DS) is a severe developmental and epileptic encephalopathy with early childhood onset. Patients with DS do not respond well to…”
Get full text
Journal Article -
3
The weekend effect for stroke patients admitted to intensive care: A retrospective cohort analysis
Published in PloS one (10-06-2020)“…Objectives To examine the effect of weekend admission on short and long-term morbidity and mortality, for patients admitted to intensive care after suffering a…”
Get full text
Journal Article -
4
An evaluation of the effectiveness of perampanel in people with epilepsy who have previously undergone resective surgery and/or implantation of a vagal nerve stimulator
Published in Epilepsy & behavior (01-03-2021)“…About 30% of people with epilepsy (PWE) are drug-resistant. Those with focal seizures may be suitable for epilepsy surgery. Those not amenable to resective…”
Get full text
Journal Article -
5
Prevalence of all epilepsies in urban informal settlements in Nairobi, Kenya: a two-stage population-based study
Published in The Lancet global health (01-08-2024)“…WHO estimates that more than 50 million people worldwide have epilepsy and 80% of cases are in low-income and middle-income countries. Most studies in Africa…”
Get full text
Journal Article -
6
Development and validation of a diagnostic aid for convulsive epilepsy in sub-Saharan Africa: a retrospective case-control study
Published in The Lancet. Digital health (01-04-2023)“…Identification of convulsive epilepsy in sub-Saharan Africa relies on access to resources that are often unavailable. Infrastructure and resource requirements…”
Get full text
Journal Article -
7
The impact of COVID‐19 on people with epilepsy: Global results from the coronavirus and epilepsy study
Published in Epilepsia open (01-10-2024)“…Objective To characterize the experience of people with epilepsy and aligned healthcare workers (HCWs) during the first 18 months of the COVID‐19 pandemic and…”
Get full text
Journal Article -
8
Development of EpiRisk: An online clinical tool for estimating the risk of major congenital malformations in pregnant women treated for epilepsy
Published in Epilepsia open (01-06-2018)“…Antiepileptic drugs (AEDs) are known to associate with an increased risk of major congenital malformations (MCMs) in children born to women who become pregnant…”
Get full text
Journal Article -
9
Small RNAs in the pathogenesis of preeclampsia
Published in Placenta (Eastbourne) (17-06-2024)“…Preeclampsia is a major contributor to maternal and fetal morbidity and mortality. The disorder can be classified into early- and late-onset subtypes, both of…”
Get full text
Journal Article -
10
A method to isolate syncytiotrophoblast-derived medium-large extracellular vesicle small RNA from maternal plasma
Published in Placenta (Eastbourne) (04-04-2024)“…Syncytiotrophoblast-derived extracellular vesicles (STB-EVs) have an important role in placental research: both as mediators of feto-maternal signalling and as…”
Get full text
Journal Article -
11
Differential 5'-tRNA Fragment Expression in Circulating Preeclampsia Syncytiotrophoblast Vesicles Drives Macrophage Inflammation
Published in Hypertension (Dallas, Tex. 1979) (01-04-2024)“…The relationship between placental pathology and the maternal syndrome of preeclampsia is incompletely characterized. Mismatch between placental nutrient…”
Get full text
Journal Article -
12
Placental capillary pericytes release excess extracellular vesicles under hypoxic conditions inducing a pro-angiogenic profile in term pregnancy
Published in Biochemical and biophysical research communications (09-04-2023)“…Pericytes are multifunctional cells wrapped around capillary endothelia, essential for vascular health, development, and blood flow regulation, although their…”
Get full text
Journal Article -
13
Exploring the capabilities of ChatGPT in women’s health: obstetrics and gynaecology
Published in npj women's health (15-07-2024)“…Artificial Intelligence (AI) is transforming healthcare, with Large Language Models (LLMs) like ChatGPT offering novel capabilities. This study evaluates…”
Get full text
Journal Article -
14
Maternal serum soluble fms-like tyrosine kinase-1–to–placental growth factor ratio distinguishes growth-restricted from non–growth-restricted small-for-gestational-age fetuses
Published in AJOG global reports (01-02-2024)“…Fetal growth restriction secondary to chronic placental insufficiency is a major cause of perinatal morbidity and mortality. A significant proportion of…”
Get full text
Journal Article -
15
Computerized Analysis of Antepartum Cardiotocography: A Review
Published in Maternal-fetal medicine (Online) (01-04-2022)Get full text
Journal Article -
16
OP 18 Comparing the sflt-1/plgf ratio with other biomarkers as a predictive test for pre-eclampsia – A clinical audit
Published in Pregnancy hypertension (01-07-2017)“…The recently published PROGNOSIS study (NEJM 2016 374:1:13–22) demonstrated the sFlt-1/PlGF ratio biomarker test to have significant clinical utility as a…”
Get full text
Journal Article -
17
Maternal serum soluble fms-like tyrosine kinase-1–to–placental growth factor ratio distinguishes growth-restricted from non–growth-restricted small-for-gestational-age fetusesAJOG Global Reports at a Glance
Published in AJOG global reports (01-02-2024)“…BACKGROUND: Fetal growth restriction secondary to chronic placental insufficiency is a major cause of perinatal morbidity and mortality. A significant…”
Get full text
Journal Article -
18
Safety, tolerability, and efficacy outcomes of the Investigation of Levetiracetam in Alzheimer's disease (ILiAD) study: a pilot, double-blind placebo-controlled crossover trial
Published in Epilepsia open (14-10-2024)“…To assess whether the antiseizure medication levetiracetam may improve cognition in individuals with Alzheimer's disease who have not previously experienced a…”
Get full text
Journal Article -
19
Mapping somatosensory connectivity in adult mice using diffusion MRI tractography and super-resolution track density imaging
Published in NeuroImage (Orlando, Fla.) (15-11-2014)“…In this study we combined ultra-high field diffusion MRI fiber tracking and super-resolution track density imaging (TDI) to map the relay locations and…”
Get full text
Journal Article -
20
PatchCTG: Patch Cardiotocography Transformer for Antepartum Fetal Health Monitoring
Published 12-11-2024“…Antepartum Cardiotocography (CTG) is vital for fetal health monitoring, but traditional methods like the Dawes-Redman system are often limited by high…”
Get full text
Journal Article