Search Results - "Davis, Verda A."

Early chronic suppression of microglial p38α in a model of Alzheimer's disease does not significantly alter amyloid-associated neuropathology by Braun, David J, Frazier, Hilaree N, Davis, Verda A, Coleman, Meggie J, Rogers, Colin B, Van Eldik, Linda J

“…The p38 alpha mitogen-activated protein kinase (p38α) is linked to both innate and adaptive immune responses and is under investigation as a target for drug…”
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A small molecule p38α MAPK inhibitor, MW150, attenuates behavioral deficits and neuronal dysfunction in a mouse model of mixed amyloid and vascular pathologies by Frazier, Hilaree N., Braun, David J., Bailey, Caleb S., Coleman, Meggie J., Davis, Verda A., Dundon, Stephen R., McLouth, Christopher J., Muzyk, Hana C., Powell, David K., Rogers, Colin B., Roy, Saktimayee M., Van Eldik, Linda J.

“…Inhibition of p38 alpha mitogen activated protein kinase (p38α) has shown great promise as a treatment for Alzheimer's disease (AD) in preclinical tests…”
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Tonic glutamate in CA1 of aging rats correlates with phasic glutamate dysregulation during seizure by Stephens, Michelle L., Williamson, Anne, Deel, Megan E., Bensalem‐Owen, Meriem, Davis, Verda A., Slevin, John, Pomerleau, Francois, Huettl, Peter, Gerhardt, Greg A.

“…Summary Objective Characterize glutamate neurotransmission in the hippocampus of awake‐behaving rodents during focal seizures in a model of aging. Methods We…”
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Kindling-induced asymmetric accumulation of hippocampal 7S SNARE complexes correlates with enhanced glutamate release by Matveeva, Elena A., Davis, Verda A., Whiteheart, Sidney W., Vanaman, Thomas C., Gerhardt, Greg A., Slevin, John T.

“…Summary Purpose:  To correlate kindling‐associated alterations of the neurotransmitter secretory machinery, glutamate release in the trisynaptic hippocampal…”
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Glutaraldehyde Cross-Linked Glutamate Oxidase Coated Microelectrode Arrays: Selectivity and Resting Levels of Glutamate in the CNS by Burmeister, Jason J, Davis, Verda A, Quintero, Jorge E, Pomerleau, Francois, Huettl, Peter, Gerhardt, Greg A

“…Glutaraldehyde is widely used as a cross-linking agent for enzyme immobilization onto microelectrodes. Recent studies and prior reports indicate changes in…”
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Cyclic AMP mediates circadian phase shifts induced by microinjection of serotonergic drugs in the hamster dorsal raphe nucleus by Duncan, Marilyn J., Davis, Verda A.

“…We have previously shown that pretreatment with a 5-HT 7 receptor antagonist, SB-269970-A, attenuated phase shifts induced by microinjections of serotonergic…”
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Short-term constant light potentiation of large-magnitude circadian phase shifts induced by 8-OH-DPAT: effects on serotonin receptors and gene expression in the hamster suprachiasmatic nucleus by Duncan, Marilyn J., Franklin, Kathleen M., Davis, Verda A., Grossman, Gregory H., Knoch, Megan E., Glass, J. David

“…Nonphotic phase‐shifting of mammalian circadian rhythms is thought to be mediated in part by serotonin (5‐HT) acting in the suprachiasmatic nucleus (SCN)…”
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Electronic (mis)communication in IACUC procedures. The more emails, the better by Davis, Verda A

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Response to Protocol Review: The More Emails, the Better by Davis, Verda A

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Early chronic suppression of microglial p38[alpha] in a model of Alzheimer's disease does not significantly alter amyloid-associated neuropathology by Braun, David J, Frazier, Hilaree N, Davis, Verda A, Coleman, Meggie J, Rogers, Colin B, Van Eldik, Linda J

“…The p38 alpha mitogen-activated protein kinase (p38[alpha]) is linked to both innate and adaptive immune responses and is under investigation as a target for…”
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Knockout of microglial P38A mapk in a mouse model of Alzheimer’s disease by Braun, David J., Davis, Verda A., Van Eldik, Linda J.

“…Background The p38a MAPK signaling pathway is a well‐established regulator of neuroinflammation, and pharmacological inhibitors of this pathway can protect…”
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Knockout of microglial P38A mapk in a mouse model of Alzheimer’s disease: Molecular and cell biology/neuroinflammation by Braun, David J., Davis, Verda A., Van Eldik, Linda J.

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Early loss of astrocyte p38alpha MAPK has sexually dimorphic impacts on measures of neuronal excitability and cytokines in aged mice by Gant, John C, Coleman, Meggie J., Davis, Verda A, Norris, Christopher M., Van Eldik, Linda J. J., Braun, David J

“…Background The p38alpha MAPK (p38) signaling pathway is ubiquitously expressed in the brain where it plays central roles in neuroinflammation, metabolism,…”
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Early loss of microglial p38α MAPK in the APPswe/PS1dE9 mouse model of Alzheimer’s disease alters soluble amyloid beta and reduces microglia co‐localization with amyloid plaques without affecting amyloid‐associated pathology by Frazier, Hilaree N, Braun, David J, Davis, Verda A, Coleman, Meggie J., Rogers, Colin B, Van Eldik, Linda J. J.

“…Background The p38 alpha mitogen‐activated protein kinase (p38α) pathway is linked to both innate and adaptive immune responses, and is currently under…”
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Early chronic suppression of microglial p38α in a model of Alzheimer's disease does not significantly alter amyloid-associated neuropathology by David J Braun, Hilaree N Frazier, Verda A Davis, Meggie J Coleman, Colin B Rogers, Linda J Van Eldik

“…The p38 alpha mitogen-activated protein kinase (p38α) is linked to both innate and adaptive immune responses and is under investigation as a target for drug…”
Get full text

Tonic glutamate in CA 1 of aging rats correlates with phasic glutamate dysregulation during seizure by Stephens, Michelle L., Williamson, Anne, Deel, Megan E., Bensalem‐Owen, Meriem, Davis, Verda A., Slevin, John, Pomerleau, Francois, Huettl, Peter, Gerhardt, Greg A.

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Electronic (Mis)Communication in IACUC Procedures by Silverman, Jerald

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