Search Results - "Davis, Stanley S"

Formulation strategies for absorption windows by Davis, Stanley S.

“…The transit of a drug (formulation) through the GI tract will determine how long a compound will be in contact with its preferred absorptive site. A good…”
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Absorption enhancers for nasal drug delivery by DAVIS, Stanley S, ILIUM, Lisbeth

“…This paper describes the basic concepts for the transmucosal delivery of drugs, and in particular the use of the nasal route for delivery of challenging drugs…”
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Advances in the use of tocols as drug delivery vehicles by CONSTANTINIDES, Panayiotis P, JIHONG HAN, DAVIS, Stanley S

“…There has been increasing interest in recent years in the drug delivery applications of tocols and their derivatives. Their biocompatibility and potential to…”
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Evaluation of Direct Transport Pathways of Glycine Receptor Antagonists and an Angiotensin Antagonist from the Nasal Cavity to the Central Nervous System in the Rat Model by Charlton, Stuart T., Whetstone, Joanne, Fayinka, Susan T., Read, Kevin D., Illum, Lisbeth, Davis, Stanley S.

“…Purpose The aim of this study was to investigate and quantify drug movement to the brain via the neuro-olfactory system after intranasal dosing of four model…”
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LEAPT: Lectin-Directed Enzyme-Activated Prodrug Therapy by Robinson, Mark A., Charlton, Stuart T., Garnier, Philippe, Wang, Xiang-tao, Davis, Stanley S., Perkins, Alan C., Frier, Malcolm, Duncan, Ruth, Savage, Tony J., Wyatt, David A., Watson, Susan A., Davis, Benjamin G., Langer, Robert

“…Targeted drug delivery to selected sites allows reduced toxicity, enhanced efficiency and interchangeable target potential [Langer, R. (2001) Science 293,…”
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Physical properties and stability of two emulsion formulations of propofol by Han, Jihong, Davis, Stanley S., Washington, Clive

“…We have compared the physical properties of two commercial emulsion formulations of the intravenous anaesthetic propofol, (Diprivan®, AstraZeneca, and Propofol…”
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Design and evaluation of an emulsion vehicle for paclitaxel. I. Physicochemical properties and plasma stability by Han, Jihong, Davis, Stanley S, Papandreou, Catherine, Melia, Colin D, Washington, Clive

“…The current formulation of paclitaxel contains ethanol and Cremophor EL and has been reported to cause serious adverse reactions. The purpose of the present…”
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Design and Evaluation of an Emulsion Vehicle for Paclitaxel. II. Suppression of the Crystallization of Paclitaxel by Freeze-Drying Technique by Han, Jihong, Washington, Clive, Davis, Stanley S.

“…Although paclitaxel is soluble in vitamin E up to 40 mg per g, crystallization was detected at loadings higher than 15 mg per g. Water appeared to be an…”
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In vitro cell interaction and in vivo biodistribution of poly(lactide-co-glycolide) nanospheres surface modified by poloxamer and poloxamine copolymers by Dunn, Susan E, Coombes, Allan G.A, Garnett, Martin C, Davis, Stanley S, Davies, Martyn C, Illum, Lisbeth

“…Biodegradable poly(lactide-co-glycolide) (PLGA) nanospheres in the size range 80–150 nm have been produced, using an interfacial polymer deposition…”
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The use of soluble polymers and polymer microparticles to provide improved vaccine responses after parenteral and mucosal delivery by Davis, Stanley S.

“…It is important when developing new vaccine systems to give proper attention to the question of delivery. In some cases the judicious choice of a delivery…”
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In vitro evaluation of the mucoadhesive properties of chitosan microspheres by He, Ping, Davis, Stanley S., Illum, Lisbeth

“…The mucoadhesive properties of chitosan and chitosan microspheres were evaluated by studying the interaction between mucin and chitosan in aqueous solution by…”
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Chitosan microspheres prepared by spray drying by He, Ping, Davis, Stanley S, Illum, Lisbeth

“…Non-crosslinked and crosslinked chitosan microspheres were prepared by a spray drying method. The microspheres so prepared had a good sphericity and a smooth…”
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Octanol−, Chloroform−, and Propylene Glycol Dipelargonat−Water Partitioning of Morphine-6-glucuronide and Other Related Opiates by Avdeef, Alex, Barrett, David A, Shaw, P. Nicholas, Knaggs, Roger D, Davis, Stanley S

“…The pK a and log P values of morphine-6-β-d-glucuronide (M6G) and morphine-3-β-d-glucuronide (M3G) and a range of structurally-related opiates (morphine,…”
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A mucosal vaccine against diphtheria: formulation of cross reacting material (CRM 197) of diphtheria toxin with chitosan enhances local and systemic antibody and Th2 responses following nasal delivery by McNeela, Edel A, O'Connor, David, Jabbal-Gill, Inderjit, Illum, Lisbeth, Davis, Stanley S, Pizza, Mariagrazia, Peppoloni, Samuele, Rappuoli, Rino, Mills, Kingston H.G

“…The development of new generation vaccines against diphtheria is dependent on the identification of antigens and routes of immunization that are capable of…”
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Evaluation of effect of ephedrine on the transport of drugs from the nasal cavity to the systemic circulation and the central nervous system by Charlton, Stuart T., Davis, Stanley S., Illum, Lisbeth

“…It has been shown that vasoconstrictive drugs such as ephedrine derivatives are able to decrease systemic absorption of drugs administered by mucosal surfaces…”
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Preparation and characterisation of rose Bengal-loaded surface-modified albumin nanoparticles by Lin, Wu, Garnett, Martin C., Davis, Stanley S., Schacht, Etienne, Ferruti, Paulo, Illum, Lisbeth

“…Surface-modified albumin nanoparticles were prepared from two poly(ethylene glycol)–human serum albumin conjugates: poly(thioetheramido acid)–poly(ethylene…”
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Parenteral polymers by Davis, Stanley S

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Preparation of biodegradable, surface engineered PLGA nanospheres with enhanced lymphatic drainage and lymph node uptake by HAWLEY, A. E, ILLUM, L, DAVIS, S. S

“…Nanospheres can be utilised for the targeting of drugs and diagnostic agents to the regional lymph nodes. The surface modification of model polystyrene, (PS),…”
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Surface modification of poly(lactide-co-glycolide) nanospheres by biodegradable poly(lactide)-poly(ethylene glycol) copolymers by STOLNIK, S, DUNN, S. E, ILLUM, L, GARNETT, M. C, DAVIES, M. C, COOMBES, A. G. A, TAYLOR, D. C, IRVING, M. P, PURKISS, S. C, TADROS, T. F, DAVIS, S. S

“…The modification of surface properties of biodegradable poly(lactide-co- glycolide) (PLGA) and model polystyrene nanospheres by poly(lactide)-poly(ethylene…”
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Structure and Mucoadhesion of Mussel Glue Protein in Dilute Solution by Deacon, Matt P, Davis, Stanley S, Waite, J. Herbert, Harding, Stephen E

“…Purified mussel adhesive protein mefp-1 (Mytilus edulis foot protein 1) has been studied regarding its state of oligomerization and gross conformation in…”
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