Search Results - "Davis, Mary D"

APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids by Zhao, Jing, Fu, Yuan, Yamazaki, Yu, Ren, Yingxue, Davis, Mary D., Liu, Chia-Chen, Lu, Wenyan, Wang, Xue, Chen, Kai, Cherukuri, Yesesri, Jia, Lin, Martens, Yuka A., Job, Lucy, Shue, Francis, Nguyen, Thanh Thanh, Younkin, Steven G., Graff-Radford, Neill R., Wszolek, Zbigniew K., Brafman, David A., Asmann, Yan W., Ertekin-Taner, Nilüfer, Kanekiyo, Takahisa, Bu, Guojun

“…APOE4 is the strongest genetic risk factor associated with late-onset Alzheimer’s disease (AD). To address the underlying mechanism, we develop cerebral…”
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Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS by Prudencio, Mercedes, Belzil, Veronique V, Batra, Ranjan, Ross, Christian A, Gendron, Tania F, Pregent, Luc J, Murray, Melissa E, Overstreet, Karen K, Piazza-Johnston, Amelia E, Desaro, Pamela, Bieniek, Kevin F, DeTure, Michael, Lee, Wing C, Biendarra, Sherri M, Davis, Mary D, Baker, Matthew C, Perkerson, Ralph B, van Blitterswijk, Marka, Stetler, Caroline T, Rademakers, Rosa, Link, Christopher D, Dickson, Dennis W, Boylan, Kevin B, Li, Hu, Petrucelli, Leonard

“…Evidence suggests that aberrant RNA processing contributes to amyotrophic lateral sclerosis (ALS). Using RNA sequencing, Prudencio et al . assessed the extent…”
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Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease by Shinohara, Mitsuru, Murray, Melissa E., Frank, Ryan D., Shinohara, Motoko, DeTure, Michael, Yamazaki, Yu, Tachibana, Masaya, Atagi, Yuka, Davis, Mary D., Liu, Chia-Chen, Zhao, Na, Painter, Meghan M., Petersen, Ronald C., Fryer, John D., Crook, Julia E., Dickson, Dennis W., Bu, Guojun, Kanekiyo, Takahisa

“…Cerebral amyloid angiopathy (CAA) often coexists with Alzheimer’s disease (AD). APOE4 is a strong genetic risk factor for both AD and CAA. Sex-dependent…”
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Tau and apolipoprotein E modulate cerebrovascular tight junction integrity independent of cerebral amyloid angiopathy in Alzheimer's disease by Liu, Chia‐Chen, Yamazaki, Yu, Heckman, Michael G., Martens, Yuka A., Jia, Lin, Yamazaki, Akari, Diehl, Nancy N., Zhao, Jing, Zhao, Na, DeTure, Michael, Davis, Mary D., Felton, Lindsey M., Qiao, Wenhui, Li, Yonghe, Li, Hongmei, Fu, Yuan, Wang, Na, Wren, Melissa, Aikawa, Tomonori, Holm, Marie‐Louise, Oue, Hiroshi, Linares, Cynthia, Allen, Mariet, Carrasquillo, Minerva M., Murray, Melissa E., Petersen, Ronald C., Ertekin‐Taner, Nilüfer, Dickson, Dennis W., Kanekiyo, Takahisa, Bu, Guojun

“…Introduction Cerebrovascular pathologies including cerebral amyloid angiopathy (CAA) and blood‐brain barrier (BBB) dysregulation are prominent features in the…”
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Author Correction: APOE4 exacerbates synapse loss and neurodegeneration in Alzheimer’s disease patient iPSC-derived cerebral organoids by Zhao, Jing, Fu, Yuan, Yamazaki, Yu, Ren, Yingxue, Davis, Mary D., Liu, Chia-Chen, Lu, Wenyan, Wang, Xue, Chen, Kai, Cherukuri, Yesesri, Jia, Lin, Martens, Yuka A., Job, Lucy, Shue, Francis, Nguyen, Thanh Thanh, Younkin, Steven G., Graff-Radford, Neill R., Wszolek, Zbigniew K., Brafman, David A., Asmann, Yan W., Ertekin-Taner, Nilüfer, Kanekiyo, Takahisa, Bu, Guojun

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APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes by Zhao, Jing, Davis, Mary D, Martens, Yuka A, Shinohara, Mitsuru, Graff-Radford, Neill R, Younkin, Steven G, Wszolek, Zbigniew K, Kanekiyo, Takahisa, Bu, Guojun

“…The ε4 allele of the APOE gene encoding apolipoprotein E (apoE) is a strong genetic risk factor for aging-related cognitive decline as well as late-onset…”
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Miro1 Marks Parkinson’s Disease Subset and Miro1 Reducer Rescues Neuron Loss in Parkinson’s Models by Hsieh, Chung-Han, Li, Li, Vanhauwaert, Roeland, Nguyen, Kong T., Davis, Mary D., Bu, Guojun, Wszolek, Zbigniew K., Wang, Xinnan

“…The identification of molecular targets and pharmacodynamic markers for Parkinson’s disease (PD) will empower more effective clinical management and…”
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APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid by Zhao, Na, Attrebi, Olivia N, Ren, Yingxue, Qiao, Wenhui, Sonustun, Berkiye, Martens, Yuka A, Meneses, Axel D, Li, Fuyao, Shue, Francis, Zheng, Jiaying, Van Ingelgom, Alexandra J, Davis, Mary D, Kurti, Aishe, Knight, Joshua A, Linares, Cynthia, Chen, Yixing, Delenclos, Marion, Liu, Chia-Chen, Fryer, John D, Asmann, Yan W, McLean, Pamela J, Dickson, Dennis W, Ross, Owen A, Bu, Guojun

“…The apolipoprotein E ( ) ε4 allele is the strongest genetic risk factor for late-onset Alzheimer's disease mainly by driving amyloid-β pathology. Recently, has…”
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APOE ε4/ε4 diminishes neurotrophic function of human iPSC-derived astrocytes by Zhao, Jing, Davis, Mary D., Martens, Yuka A., Shinohara, Mitsuru, Graff-Radford, Neill R., Younkin, Steven G., Wszolek, Zbigniew K., Kanekiyo, Takahisa, Bu, Guojun

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Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids by Zhao, Jing, Lu, Wenyan, Ren, Yingxue, Fu, Yuan, Martens, Yuka A., Shue, Francis, Davis, Mary D., Wang, Xue, Chen, Kai, Li, Fuyao, Liu, Chia-Chen, Graff-Radford, Neill R., Wszolek, Zbigniew K., Younkin, Steven G., Brafman, David A., Ertekin-Taner, Nilüfer, Asmann, Yan W., Dickson, Dennis W., Xu, Ziying, Pan, Meixia, Han, Xianlin, Kanekiyo, Takahisa, Bu, Guojun

“…APOE4 is a strong genetic risk factor for Alzheimer’s disease and Dementia with Lewy bodies; however, how its expression impacts pathogenic pathways in a…”
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Correction to: Apolipoprotein E regulates lipid metabolism and α‑synuclein pathology in human iPSC‑derived cerebral organoids by Zhao, Jing, Lu, Wenyan, Ren, Yingxue, Fu, Yuan, Martens, Yuka A., Shue, Francis, Davis, Mary D., Wang, Xue, Chen, Kai, Li, Fuyao, Liu, Chia-Chen, Graff-Radford, Neill R., Wszolek, Zbigniew K., Younkin, Steven G., Brafman, David A., Ertekin-Taner, Nilüfer, Asmann, Yan W., Dickson, Dennis W., Xu, Ziying, Pan, Meixia, Han, Xianlin, Kanekiyo, Takahisa, Bu, Guojun

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Frontotemporal dementia-associated N279K tau mutant disrupts subcellular vesicle trafficking and induces cellular stress in iPSC-derived neural stem cells by Wren, Melissa C, Zhao, Jing, Liu, Chia-Chen, Murray, Melissa E, Atagi, Yuka, Davis, Mary D, Fu, Yuan, Okano, Hirotaka J, Ogaki, Kotaro, Strongosky, Audrey J, Tacik, Pawel, Rademakers, Rosa, Ross, Owen A, Dickson, Dennis W, Wszolek, Zbigniew K, Kanekiyo, Takahisa, Bu, Guojun

“…Pallido-ponto-nigral degeneration (PPND), a major subtype of frontotemporal dementia with parkinsonism related to chromosome 17 (FTDP-17), is a progressive and…”
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Modeling Lewy body disease with SNCA triplication iPSC-derived cortical organoids and identifying therapeutic drugs by Jin, Yunjung, Li, Fuyao, Li, Zonghua, Ikezu, Tadafumi C, O'Leary, Justin, Selvaraj, Manikandan, Zhu, Yiyang, Martens, Yuka A, Koga, Shunsuke, Santhakumar, Hannah, Li, Yonghe, Lu, Wenyan, You, Yang, Lolo, Kiara, DeTure, Michael, Beasley, Alexandra I, Davis, Mary D, McLean, Pamela J, Ross, Owen A, Kanekiyo, Takahisa, Ikezu, Tsuneya, Caulfield, Thomas, Carr, Jonathan, Wszolek, Zbigniew K, Bu, Guojun, Dickson, Dennis W, Zhao, Na

“…Aggregated α-synuclein (α-SYN) proteins, encoded by the gene, are hallmarks of Lewy body disease (LBD), affecting multiple brain regions. However, the specific…”
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Regenerative Medicine in the State of Florida: Letter Outlining the Florida Organization for Regenerative Medicine by Bruce, Charles J., Bu, Guojun, Centanni, John M., Davis, Mary D., Dobson, Jon, Hare, Joshua M., Fields, Gregg B., Jove, Richard, Kenyon, Norma, Khan, Aisha, March, Keith, Matosevic, Sandro, Mahmood, Ayesha, Pepine, Carl J., Ricordi, Camillo, Shapiro, Shane A., Zylberberg, Claudia, Zylberberg, Ezequiel

“…The proliferation of new models like the Centre for Commercialization of Regenerative Medicine (CCRM) in Canada, the California Institute for Regenerative…”
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Correction to: Apolipoprotein E regulates lipid metabolism and [alpha]âsynuclein pathology in human iPSCâderived cerebral organoids by Zhao, Jing, Lu, Wenyan, Ren, Yingxue, Fu, Yuan, Martens, Yuka A, Shue, Francis, Davis, Mary D

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Apolipoprotein E regulates lipid metabolism and [alpha]-synuclein pathology in human iPSC-derived cerebral organoids by Zhao, Jing, Lu, Wenyan, Ren, Yingxue, Fu, Yuan, Martens, Yuka A, Shue, Francis, Davis, Mary D

“…APOE4 is a strong genetic risk factor for Alzheimer's disease and Dementia with Lewy bodies; however, how its expression impacts pathogenic pathways in a…”
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Applications of Vapor Pressure Measurements by Davis, H. S, Davis, Mary D

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The Detection of Arsenic in Sulfur by Davis, Harold S., Davis, Mary D.

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An Exchange on Lay Leadership/Response from Peter J. Giammalvo, PhD/Response from John O. Mudd, JD by Davis, Mary D, Giammalvo, Peter J, Mudd, John O

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A system for sharing routine surgical pathology specimens across institutions: the Shared Pathology Informatics Network by Drake, Thomas A., MD, Braun, Jonathan, MD, PhD, Marchevsky, Alberto, MD, Kohane, Isaac S., MD, PhD, Fletcher, Christopher, MD, FRCPath, Chueh, Henry, MD, MS, Beckwith, Bruce, MD, Berkowicz, David, MD, Kuo, Frank, MD, PhD, Zeng, Qing T., PhD, Balis, Ulysses, MD, Holzbach, Ana, PhD, McMurry, Andrew, Gee, Connie E., PhD, McDonald, Clement J., MD, Schadow, Gunther, MD, PhD, Davis, Mary, MD, Hattab, Eyas M., MD, Blevins, Lonnie, Hook, John, Becich, Michael, MD, PhD, Crowley, Rebecca S., MD, MS, Taube, Sheila E., PhD, Berman, Jules, PhD, MD

“…Summary This report presents an overview for pathologists of the development and potential applications of a novel Web enabled system allowing indexing and…”
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