Search Results - "Davis, Kathryn A"
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Interictal epileptiform activity outside the seizure onset zone impacts cognition
Published in Brain (London, England : 1878) (01-08-2017)“…See Kleen and Kirsch (doi:10.1093/awx178) for a scientific commentary on this article.Cognitive deficits are common among epilepsy patients. In these patients,…”
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Spatial distribution of interictal spikes fluctuates over time and localizes seizure onset
Published in Brain (London, England : 1878) (01-02-2020)“…The location of interictal spikes is used to aid surgical planning in patients with medically refractory epilepsy; however, their spatial and temporal dynamics…”
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What life course theoretical models best explain the relationship between exposure to childhood adversity and psychopathology symptoms: recency, accumulation, or sensitive periods?
Published in Psychological medicine (01-11-2018)“…Although childhood adversity is a potent determinant of psychopathology, relatively little is known about how the characteristics of adversity exposure,…”
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Closed-loop stimulation of temporal cortex rescues functional networks and improves memory
Published in Nature communications (06-02-2018)“…Memory failures are frustrating and often the result of ineffective encoding. One approach to improving memory outcomes is through direct modulation of brain…”
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Dynamic Network Drivers of Seizure Generation, Propagation and Termination in Human Neocortical Epilepsy
Published in PLoS computational biology (01-12-2015)“…The epileptic network is characterized by pathologic, seizure-generating 'foci' embedded in a web of structural and functional connections. Clinically, seizure…”
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White Matter Network Architecture Guides Direct Electrical Stimulation through Optimal State Transitions
Published in Cell reports (Cambridge) (03-09-2019)“…Optimizing direct electrical stimulation for the treatment of neurological disease remains difficult due to an incomplete understanding of its physical…”
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Characterizing the role of the structural connectome in seizure dynamics
Published in Brain (London, England : 1878) (01-07-2019)“…How does the human brain's structural scaffold give rise to its intricate functional dynamics? This is a central question in translational neuroscience that is…”
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Direct Brain Stimulation Modulates Encoding States and Memory Performance in Humans
Published in Current biology (08-05-2017)“…People often forget information because they fail to effectively encode it. Here, we test the hypothesis that targeted electrical stimulation can modulate…”
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Lateralized hippocampal oscillations underlie distinct aspects of human spatial memory and navigation
Published in Nature communications (21-06-2018)“…The hippocampus plays a vital role in various aspects of cognition including both memory and spatial navigation. To understand electrophysiologically how the…”
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Quantitative EEG predicts outcomes in children after cardiac arrest
Published in Neurology (14-05-2019)“…OBJECTIVETo determine whether quantitative EEG (QEEG) features predict neurologic outcomes in children after cardiac arrest. METHODSWe performed a…”
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A framework For brain atlases: Lessons from seizure dynamics
Published in NeuroImage (Orlando, Fla.) (01-07-2022)“…•Brain atlases include a diverse set of maps of the brain and contain a wide variety of features used throughout the neuroscience community.•A framework for…”
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Data integration: Combined imaging and electrophysiology data in the cloud
Published in NeuroImage (Orlando, Fla.) (01-01-2016)“…There has been an increasing effort to correlate electrophysiology data with imaging in patients with refractory epilepsy over recent years. IEEG.org provides…”
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Mechanistic target of rapamycin complex 1 and 2 in human temporal lobe epilepsy
Published in Annals of neurology (01-02-2018)“…Objective Temporal lobe epilepsy (TLE) is a chronic epilepsy syndrome defined by seizures and progressive neurological disabilities, including cognitive…”
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Universal automated high frequency oscillation detector for real-time, long term EEG
Published in Clinical neurophysiology (01-02-2016)“…Highlights • An unsupervised, automated detector runs faster than real time and identified nearly 1.5 million HFOs that were spatially correlated with…”
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Resting state functional connectivity demonstrates increased segregation in bilateral temporal lobe epilepsy
Published in Epilepsia (Copenhagen) (01-05-2023)“…Objective Temporal lobe epilepsy (TLE) is the most common type of focal epilepsy. An increasingly identified subset of patients with TLE consists of those who…”
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The effects of direct brain stimulation in humans depend on frequency, amplitude, and white-matter proximity
Published in Brain stimulation (01-09-2020)“…Researchers have used direct electrical brain stimulation to treat a range of neurological and psychiatric disorders. However, for brain stimulation to be…”
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Predictive modeling of evoked intracranial EEG response to medial temporal lobe stimulation in patients with epilepsy
Published in Communications biology (28-09-2024)“…Despite promising advancements, closed-loop neurostimulation for drug-resistant epilepsy (DRE) still relies on manual tuning and produces variable outcomes,…”
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Quantifying trial‐by‐trial variability during cortico‐cortical evoked potential mapping of epileptogenic tissue
Published in Epilepsia (Copenhagen) (01-04-2023)“…Objective Measuring cortico‐cortical evoked potentials (CCEPs) is a promising tool for mapping epileptic networks, but it is not known how variability in brain…”
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Similar patterns of neural activity predict memory function during encoding and retrieval
Published in NeuroImage (Orlando, Fla.) (15-07-2017)“…Neural networks that span the medial temporal lobe (MTL), prefrontal cortex, and posterior cortical regions are essential to episodic memory function in…”
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Mapping the structural and functional network architecture of the medial temporal lobe using 7T MRI
Published in Human brain mapping (01-02-2018)“…Medial temporal lobe (MTL) subregions play integral roles in memory function and are differentially affected in various neurological and psychiatric disorders…”
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