Search Results - "Davis, Justin W"

Differential susceptibility to colorectal cancer due to naturally occurring gut microbiota by Ericsson, Aaron C, Akter, Sadia, Hanson, Marina M, Busi, Susheel B, Parker, Taybor W, Schehr, Rebecca J, Hankins, Miriam A, Ahner, Carin E, Davis, Justin W, Franklin, Craig L, Amos-Landgraf, James M, Bryda, Elizabeth C

“…Recent studies investigating the human microbiome have identified particular bacterial species that correlate with the presence of colorectal cancer. To…”
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Reduced ITPase activity and favorable IL28B genetic variant protect against ribavirin-induced anemia in interferon-free regimens by Vasanthakumar, Aparna, Davis, Justin W, Abunimeh, Manal, Söderholm, Jonas, Zha, Jiuhong, Dumas, Emily O, Cohen, Daniel E, Waring, Jeffrey F, Lagging, Martin

“…Genetic variants of inosine triphosphatase (ITPA) that confer reduced ITPase activity are associated with protection against ribavirin(RBV)-induced hemolytic…”
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The Clinical Response of Upadacitinib and Risankizumab Is Associated With Reduced Inflammatory Bowel Disease Anti-TNF-α Inadequate Response Mechanisms by Wang, Jing, Macoritto, Michael, Guay, Heath, Davis, Justin W, Levesque, Marc C, Cao, Xiaohong

“…Abstract Background Janus kinase (JAK) 1 inhibitor upadacitinib and IL-23 inhibitor risankizumab are efficacious in inflammatory bowel disease (IBD) patients…”
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Pathological response in children and adults with large unresected intermediate-grade or high-grade soft tissue sarcoma receiving preoperative chemoradiotherapy with or without pazopanib (ARST1321): a multicentre, randomised, open-label, phase 2 trial by Weiss, Aaron R, Chen, Yen-Lin, Scharschmidt, Thomas J, Chi, Yueh-Yun, Tian, Jing, Black, Jennifer O, Davis, Jessica L, Fanburg-Smith, Julie C, Zambrano, Eduardo, Anderson, James, Arens, Robin, Binitie, Odion, Choy, Edwin, Davis, Justin W, Hayes-Jordan, Andrea, Kao, Simon C, Kayton, Mark L, Kessel, Sandy, Lim, Ruth, Meyer, William H, Million, Lynn, Okuno, Scott H, Ostrenga, Andrew, Parisi, Marguerite T, Pryma, Daniel A, Randall, R Lor, Rosen, Mark A, Schlapkohl, Mary, Shulkin, Barry L, Smith, Ethan A, Sorger, Joel I, Terezakis, Stephanie, Hawkins, Douglas S, Spunt, Sheri L, Wang, Dian

“…Outcomes for children and adults with advanced soft tissue sarcoma are poor with traditional therapy. We investigated whether the addition of pazopanib to…”
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Psoriatic skin molecular and histopathologic profiles after treatment with risankizumab versus ustekinumab by Visvanathan, Sudha, Baum, Patrick, Vinisko, Richard, Schmid, Ramona, Flack, Mary, Lalovic, Bojan, Kleiner, Oliver, Fuentes-Duculan, Judilyn, Garcet, Sandra, Davis, Justin W., Grebe, Kristie M., Fine, Jay S., Padula, Steven J., Krueger, James G.

“…IL-23 contributes to the activation, maintenance, and proliferation of TH17 cells and plays a major role in psoriasis pathophysiology. IL-23p19 inhibition with…”
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Association of peripheral blood DNA methylation level with Alzheimer's disease progression by Li, Qingqin S, Vasanthakumar, Aparna, Davis, Justin W, Idler, Kenneth B, Nho, Kwangsik, Waring, Jeffrey F, Saykin, Andrew J

“…Identifying biomarkers associated with Alzheimer's disease (AD) progression may enable patient enrichment and improve clinical trial designs. Epigenome-wide…”
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Harnessing peripheral DNA methylation differences in the Alzheimer's Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease by Vasanthakumar, Aparna, Davis, Justin W, Idler, Kenneth, Waring, Jeffrey F, Asque, Elizabeth, Riley-Gillis, Bridget, Grosskurth, Shaun, Srivastava, Gyan, Kim, Sungeun, Nho, Kwangsik, Nudelman, Kelly N H, Faber, Kelley, Sun, Yu, Foroud, Tatiana M, Estrada, Karol, Apostolova, Liana G, Li, Qingqin S, Saykin, Andrew J

“…Alzheimer's disease (AD) is a chronic progressive neurodegenerative disease impacting an estimated 44 million adults worldwide. The causal pathology of AD…”
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Selective IL-23 Inhibition by Risankizumab Modulates the Molecular Profile in the Colon and Ileum of Patients With Active Crohn's Disease: Results From a Randomised Phase II Biopsy Sub-study by Visvanathan, Sudha, Baum, Patrick, Salas, Azucena, Vinisko, Richard, Schmid, Ramona, Grebe, Kristie M, Davis, Justin W, Wallace, Kori, Böcher, Wulf O, Padula, Steven J, Fine, Jay S, Panés, Julián

“…We aimed to investigate the underlying mechanism of action of risankizumab, a monoclonal antibody targeting the IL-23 p19 subunit, previously reported to…”
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Telomere Shortening in the Alzheimer's Disease Neuroimaging Initiative Cohort by Nudelman, Kelly N H, Lin, Jue, Lane, Kathleen A, Nho, Kwangsik, Kim, Sungeun, Faber, Kelley M, Risacher, Shannon L, Foroud, Tatiana M, Gao, Sujuan, Davis, Justin W, Weiner, Michael W, Saykin, Andrew J

“…Although shorter telomeres have been associated with Alzheimer's disease (AD), it is unclear whether longitudinal change in telomere length is associated with…”
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Integrative analysis of DNA methylation and gene expression identifies genes associated with biological aging in Alzheimer's disease by Kim, Bo‐Hyun, Vasanthakumar, Aparna, Li, Qingqin S., Nudelman, Kelly N.H., Risacher, Shannon L., Davis, Justin W., Idler, Kenneth, Lee, Jong‐Min, Seo, Sang Won, Waring, Jeffrey F., Saykin, Andrew J., Nho, Kwangsik

“…Introduction The acceleration of biological aging is a risk factor for Alzheimer's disease (AD). Here, we performed weighted gene co‐expression network…”
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Comparison of exposure response relationship of atrasentan between North American and Asian populations by Heerspink, Hiddo J. L., Makino, Hirofumi, Andress, Dennis, Brennan, John J., Correa‐Rotter, Ricardo, Coll, Blai, Davis, Justin W., Idler, Ken, Kohan, Donald E., Liu, Mohan, Perkovic, Vlado, Remuzzi, Giuseppe, Tobe, Sheldon W., Toto, Robert, Parving, Hans‐Henrik, de Zeeuw, Dick

“…Aims The selective endothelin (ET) A receptor antagonist atrasentan has been shown to lower albuminuria in North American and Asian patients with type 2…”
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In vivo tropisms and kinetics of rat theilovirus infection in immunocompetent and immunodeficient rats by Drake, Michael T., Besch-Williford, Cindy, Myles, Matthew H., Davis, Justin W., Livingston, Robert S.

“…► Introduce a rat model to study Theilovirus pathogenesis. ► Rat Theilovirus 1 has tropisms for the epithelial cells of the small intestine. ► Sustained high…”
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Association of peripheral blood DNA methylation levels with Alzheimer’s disease progression by Li, Qingqin S., Vasanthakumar, Aparna, Davis, Justin W., Idler, Kenneth, Nho, Kwangsik, Waring, Jeffrey, Saykin, Andrew J.

“…Background Identifying biomarkers associated with Alzheimer’s disease (AD) progression may enable patient enrichment and improve clinical trial designs…”
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Tu1763 – Systemic and Tissue Modulation of Il-23 Pathway Biomarkers in a Phase 2 Study of Risankizumab in Patients with Crohn's Disease by Salas, Azucena, Grebe, Kristie, Powell, Nick, Panes, Julian, Davis, Justin W., Hong, Feng, Pang, Yinuo, Suleiman, Ahmed, Wallace, Kori, Feagan, Brian G.

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Pathologic response in children and adults with large unresected intermediate- or high-grade soft tissue sarcoma receiving preoperative chemoradiation with or without pazopanib (ARST1321; PAZNTIS): a multicentre, randomised, open-label, phase 2 trial by Weiss, Aaron R., Chen, Yen-Lin, Scharschmidt, Thomas J., Chi, Yueh-Yun, Tian, Jing, Black, Jennifer O., Davis, Jessica L., Fanburg-Smith, Julie C., Zambrano, Eduardo, Anderson, James, Arens, Robin, Binitie, Odion, Choy, Edwin, Davis, Justin W., Hayes-Jordan, Andrea, Kao, Simon C., Kayton, Mark L., Kessel, Sandy, Lim, Ruth, Meyer, William H., Million, Lynn, Okuno, Scott H., Ostrenga, Andrew, Parisi, Marguerite T., Pryma, Daniel A., Randall, R. Lor, Rosen, Mark A., Schlapkohl, Mary, Shulkin, Barry L., Smith, Ethan A., Sorger, Joel I., Terezakis, Stephanie, Hawkins, Douglas S., Spunt, Sheri L., Wang, Dian

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DNA METHYLATION DYNAMICS IN ALZHEIMER’S DISEASE: DEVELOPMENT OF BIOMARKERS AND NOVEL DRUG TARGETS USING ADNI EPIGENETIC DATA by Vasanthakumar, Aparna, Davis, Justin W., Idler, Kenneth, Asque, Elizabeth, Riley-Gillis, Bridget, Kim, Sungeun, Nho, Kwangsik, Nudelman, Kelly N.H., Faber, Kelley, Bai, Yuchen, Sun, Yu, Foroud, Tatiana M., Estrada, Karol, Apostolova, Liana G., Li, Qingqin S., Saykin, Andrew J., Waring, Jeffrey

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P3‐120: DNA METHYLATION DYNAMICS IN ALZHEIMER'S DISEASE: DEVELOPMENT OF BIOMARKERS AND NOVEL DRUG TARGETS USING ADNI EPIGENETIC DATA by Vasanthakumar, Aparna, Davis, Justin W., Idler, Kenneth, Asque, Elizabeth, Riley-Gillis, Bridget, Kim, Sungeun, Nho, Kwangsik, Nudelman, Kelly N.H., Faber, Kelley, Bai, Yuchen, Sun, Yu, Foroud, Tatiana M., Estrada, Karol, Apostolova, Liana G., Li, Qingqin S., Saykin, Andrew J., Waring, Jeffrey

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Comparison of exposure response relationship of atrasentan between N orth A merican and A sian populations by Heerspink, Hiddo J. L., Makino, Hirofumi, Andress, Dennis, Brennan, John J., Correa‐Rotter, Ricardo, Coll, Blai, Davis, Justin W., Idler, Ken, Kohan, Donald E., Liu, Mohan, Perkovic, Vlado, Remuzzi, Giuseppe, Tobe, Sheldon W., Toto, Robert, Parving, Hans‐Henrik, de Zeeuw, Dick

“…Aims The selective endothelin ( ET ) A receptor antagonist atrasentan has been shown to lower albuminuria in N orth A merican and A sian patients with type 2…”
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DNA METHYLATION DYNAMICS IN ALZHEIMER’S DISEASE DIAGNOSIS AND PROGRESSION by Vasanthakumar, Aparna, Davis, Justin W., Idler, Kenneth, Kim, Sungeun, Nho, Kwangsik, Nudelman, Kelly N.H., Faber, Kelley, Bai, Yuchen, Foroud, Tatiana M., Estrada, Karol, Li, Qingqin, Saykin, Andrew J., Waring, Jeffrey

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P3‐120: DNA METHYLATION DYNAMICS IN ALZHEIMER'S DISEASE: DEVELOPMENT OF BIOMARKERS AND NOVEL DRUG TARGETS USING ADNI EPIGENETIC DATA by Vasanthakumar, Aparna, Davis, Justin W., Idler, Kenneth, Asque, Elizabeth, Riley-Gillis, Bridget, Kim, Sungeun, Nho, Kwangsik, Nudelman, Kelly N.H., Faber, Kelley, Bai, Yuchen, Sun, Yu, Foroud, Tatiana M., Estrada, Karol, Apostolova, Liana G., Li, Qingqin S., Saykin, Andrew J., Waring, Jeffrey

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