Search Results - "Davis, Julian R. E"

Dynamic analysis of stochastic transcription cycles by Harper, Claire V, Finkenstädt, Bärbel, Woodcock, Dan J, Friedrichsen, Sönke, Semprini, Sabrina, Ashall, Louise, Spiller, David G, Mullins, John J, Rand, David A, Davis, Julian R E, White, Michael R H

“…In individual mammalian cells the expression of some genes such as prolactin is highly variable over time and has been suggested to occur in stochastic pulses…”
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Acromegaly surgery in Manchester revisited - The impact of reducing surgeon numbers and the 2010 consensus guidelines for disease remission by Wang, Yi Yuen, Higham, Claire, Kearney, Tara, Davis, Julian R.E., Trainer, Peter, Gnanalingham, Kanna K.

“…Summary Introduction  Surgical remission rates for acromegaly vary and are dependent on the tumour morphology, biochemical definition of disease remission and…”
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The Role of the Aryl Hydrocarbon Receptor-Interacting Protein Gene in Familial and Sporadic Pituitary Adenomas by Leontiou, Chrysanthia A., Gueorguiev, Maria, van der Spuy, Jacqueline, Quinton, Richard, Lolli, Francesca, Hassan, Sevda, Chahal, Harvinder S., Igreja, Susana C., Jordan, Suzanne, Rowe, Janice, Stolbrink, Marie, Christian, Helen C., Wray, Jessica, Bishop-Bailey, David, Berney, Dan M., Wass, John A. H., Popovic, Vera, Ribeiro-Oliveira, Antônio, Gadelha, Monica R., Monson, John P., Akker, Scott A., Davis, Julian R. E., Clayton, Richard N., Yoshimoto, Katsuhiko, Iwata, Takeo, Matsuno, Akira, Eguchi, Kuniki, Musat, Mâdâlina, Flanagan, Daniel, Peters, Gordon, Bolger, Graeme B., Chapple, J. Paul, Frohman, Lawrence A., Grossman, Ashley B., Korbonits, Márta

“…Context: Mutations have been identified in the aryl hydrocarbon receptor-interacting protein (AIP) gene in familial isolated pituitary adenomas (FIPA). It is…”
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Disentangling juxtacrine from paracrine signalling in dynamic tissue by Momiji, Hiroshi, Hassall, Kirsty L, Featherstone, Karen, McNamara, Anne V, Patist, Amanda L, Spiller, David G, Christian, Helen C, White, Michael R H, Davis, Julian R E, Finkenstädt, Bärbel F, Rand, David A

“…Prolactin is a major hormone product of the pituitary gland, the central endocrine regulator. Despite its physiological importance, the cell-level mechanisms…”
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Identification of Melatonin-Regulated Genes in the Ovine Pituitary Pars Tuberalis, a Target Site for Seasonal Hormone Control by Dupré, Sandrine M, Burt, Dave W, Talbot, Richard, Downing, Alison, Mouzaki, Daphne, Waddington, David, Malpaux, Benoit, Davis, Julian R. E, Lincoln, Gerald A, Loudon, Andrew S. I

“…The pars tuberalis (PT) of the pituitary gland expresses a high density of melatonin (MEL) receptors and is believed to regulate seasonal physiology by…”
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Spatially coordinated dynamic gene transcription in living pituitary tissue by Featherstone, Karen, Hey, Kirsty, Momiji, Hiroshi, McNamara, Anne V, Patist, Amanda L, Woodburn, Joanna, Spiller, David G, Christian, Helen C, McNeilly, Alan S, Mullins, John J, Finkenstädt, Bärbel F, Rand, David A, White, Michael R H, Davis, Julian R E

“…Transcription at individual genes in single cells is often pulsatile and stochastic. A key question emerges regarding how this behaviour contributes to tissue…”
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Reconstruction of transcriptional dynamics from gene reporter data using differential equations by Finkenstädt, Bärbel, Heron, Elizabeth A., Komorowski, Michal, Edwards, Kieron, Tang, Sanyi, Harper, Claire V., Davis, Julian R. E., White, Michael R. H., Millar, Andrew J., Rand, David A.

“…Motivation: Promoter-driven reporter genes, notably luciferase and green fluorescent protein, provide a tool for the generation of a vast array of time-course…”
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Perrault syndrome: further evidence for genetic heterogeneity by Jenkinson, Emma M., Clayton-Smith, Jill, Mehta, Sarju, Bennett, Christopher, Reardon, Willie, Green, Andrew, Pearce, Simon H. S., De Michele, Giuseppe, Conway, Gerard S., Cilliers, Deirdre, Moreton, Natalie, Davis, Julian R. E., Trump, Dorothy, Newman, William G.

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Peritonitis Activates Transcription of the Human Prolactin Locus in Myeloid Cells in a Humanized Transgenic Rat Model by Semprini, Sabrina, McNamara, Anne V, Awais, Raheela, Featherstone, Karen, Harper, Claire V, McNeilly, Judith R, Patist, Amanda, Rossi, Adriano G, Dransfield, Ian, McNeilly, Alan S, Davis, Julian R.E, White, Michael R.H, Mullins, John J

“…Prolactin (PRL) is mainly expressed in the pituitary in rodents, whereas in humans, expression is observed in many extrapituitary sites, including lymphocytes…”
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Perrault Syndrome Is Caused by Recessive Mutations in CLPP, Encoding a Mitochondrial ATP-Dependent Chambered Protease by Jenkinson, Emma M., Rehman, Atteeq U., Walsh, Tom, Clayton-Smith, Jill, Lee, Kwanghyuk, Morell, Robert J., Drummond, Meghan C., Khan, Shaheen N., Naeem, Muhammad Asif, Rauf, Bushra, Billington, Neil, Schultz, Julie M., Urquhart, Jill E., Lee, Ming K., Berry, Andrew, Hanley, Neil A., Mehta, Sarju, Cilliers, Deirdre, Clayton, Peter E., Kingston, Helen, Smith, Miriam J., Warner, Thomas T., Black, Graeme C., Trump, Dorothy, Davis, Julian R.E., Ahmad, Wasim, Leal, Suzanne M., Riazuddin, Sheikh, King, Mary-Claire, Friedman, Thomas B., Newman, William G.

“…Perrault syndrome is a genetically and clinically heterogeneous autosomal-recessive condition characterized by sensorineural hearing loss and ovarian failure…”
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Calcium dynamics and chromatin remodelling underlie heterogeneity in prolactin transcription by Harper, Claire V, McNamara, Anne V, Spiller, David G, Charnock, Jayne C, White, Michael R H, Davis, Julian R E

“…Pituitary cells have been reported to show spontaneous calcium oscillations and dynamic transcription cycles. To study both processes in the same living cell…”
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Transition in endocrinology: the challenge of maintaining continuity by Downing, Jennifer, Gleeson, Helena K., Clayton, Peter E., Davis, Julian R. E., Wales, Jerry K., Callery, Peter

“…Objective Transition from child to adult status is a crucial stage in young people's lives. It is important that young people continue to receive appropriate…”
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Transient asystole during endoscopic transsphenoidal surgery for Acromegaly: an example of trigeminocardiac reflex by Abou-Zeid, Ahmed H, Davis, Julian R. E, Kearney, Tara, Gnanalingham, Kanna K

“…Cardiac arrhythmias are rare during transsphenoidal surgery and is often secondary to stimulation of the trigeminal nerve endings that supply the nasal…”
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Tumor Necrosis Factor-α Activates the Human Prolactin Gene Promoter via Nuclear Factor-κB Signaling by Friedrichsen, Sönke, Harper, Claire V, Semprini, Sabrina, Wilding, Michael, Adamson, Antony D, Spiller, Dave G, Nelson, Glyn, Mullins, John J, White, Michael R. H, Davis, Julian R. E

“…Pituitary function has been shown to be regulated by an increasing number of intrapituitary factors, including cytokines. Here we show that the important…”
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A stochastic transcriptional switch model for single cell imaging data by Hey, Kirsty L, Momiji, Hiroshi, Featherstone, Karen, Davis, Julian R E, White, Michael R H, Rand, David A, Finkenstädt, Bärbel

“…Gene expression is made up of inherently stochastic processes within single cells and can be modeled through stochastic reaction networks (SRNs). In…”
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Newly recognized recessive syndrome characterized by dysmorphic features, hypogonadotropic hypogonadism, severe microcephaly, and sensorineural hearing loss maps to 3p21.3 by Jenkinson, Emma M., Kingston, Helen, Urquhart, Jill, Khan, Naz, Melville, Athalie, Swinton, Martin, Crow, Yanick J., Davis, Julian R.E., Trump, Dorothy, Newman, William G.

“…We present a newly recognized, likely autosomal recessive, pleiotropic disorder seen in four individuals (three siblings and their nephew) from a…”
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Role of Estrogen Response Element in the Human Prolactin Gene: Transcriptional Response and Timing by McNamara, Anne V, Adamson, Antony D, Dunham, Lee S. S, Semprini, Sabrina, Spiller, David G, McNeilly, Alan S, Mullins, John J, Davis, Julian R. E, White, Michael R. H

“…The use of bacterial artificial chromosome (BAC) reporter constructs in molecular physiology enables the inclusion of large sections of flanking DNA, likely to…”
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No Difference in Mood and Quality of Life in DHEA-S Deficient Adults with Addison's Disease vs. Type 2 Diabetes Patients with Normal DHEA-S Levels: Implications for Management of These Conditions by Heald, Adrian H, Walther, Andreas, Davis, Julian R E, Moreno, Gabriela Y C, Kane, John, Livingston, Mark, Fowler, Helen L

“…Patients with Addison's disease have relatively high rates of depression and anxiety symptoms compared with population-based reference samples. Addison's…”
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Dynamic organisation of prolactin gene expression in living pituitary tissue by Harper, Claire V, Featherstone, Karen, Semprini, Sabrina, Friedrichsen, Sönke, McNeilly, Judith, Paszek, Pawel, Spiller, David G, McNeilly, Alan S, Mullins, John J, Davis, Julian R.E, White, Michael R.H

“…Gene expression in living cells is highly dynamic, but temporal patterns of gene expression in intact tissues are largely unknown. The mammalian pituitary…”
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Identification of Eya3 and TAC1 as Long-Day Signals in the Sheep Pituitary by Dupré, Sandrine M., Miedzinska, Katarzyna, Duval, Chloe V., Yu, Le, Goodman, Robert L., Lincoln, Gerald A., Davis, Julian R.E., McNeilly, Alan S., Burt, David D., Loudon, Andrew S.I.

“…Seasonally breeding mammals such as sheep use photoperiod, encoded by the nocturnal secretion of the pineal hormone melatonin, as a critical cue to drive…”
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