Search Results - "Davis, Ellen M."
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Structural and Biochemical Characterization of the Catalytic Core of the Metastatic Factor P-Rex1 and Its Regulation by PtdIns(3,4,5)P3
Published in Structure (London) (03-05-2016)“…Phosphatidylinositol 3,4,5-trisphosphate (PIP3)-dependent Rac exchanger 1 (P-Rex1) is a Rho guanine nucleotide exchange factor synergistically activated by…”
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1911-P: The Physiological Role of GLP-1 in Regulating Pancreatic Inflammation in a Sepsis Model
Published in Diabetes (New York, N.Y.) (01-06-2020)“…Patients who have diabetes mellitus (both type 1 and type 2) have increased susceptibility to sepsis. Among the hormones that are altered by sepsis, there is…”
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2488-PUB: The Role of GLP-1 in Metabolic Responses during Sepsis
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Sepsis is characterized by a dysregulated immune response that can result in end organ damage and is the number one cause of death in the ICU. Among the…”
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Structural and Functional Characterization of the Metastatic RhoGEF P‐Rex1 and its Regulation by PtdIns(3,4,5) P 3 : Towards Inhibitory Small Molecule Development
Published in The FASEB journal (01-04-2016)“…Abstract only Phosphatidylinositol 3,4,5‐trisphosphate (PIP 3 )‐dependent Rac exchanger 1 (P‐Rex1) is a Rho guanine‐nucleotide exchange factor (RhoGEF) that…”
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GLP-1 Integrates the Innate Immune System to Glucose Homeostasis
Published in Diabetes (New York, N.Y.) (01-07-2018)“…Glucagon-like peptide-1 (GLP-1) is a gut peptide that increases post prandially and functions to increase insulin secretion and improve glucose homeostasis…”
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Structural and Functional Studies of the Metastatic Factors P‐Rex1 and P‐Rex2: Toward Small Molecule Inhibitor Development
Published in The FASEB journal (01-04-2017)“…Abstract only Phosphatidylinositol 3,4,5‐trisphosphate (PIP 3 )‐dependent Rac exchanger 1 (P‐Rex1) is a Rho guanine‐nucleotide exchange factor (RhoGEF) that…”
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Readers' Guide to Periodical Literature and Magazine Index: A Comparison
Published in Reference services review (01-04-1983)“…Since 1901 the public has relied on H.W. Wilson's Readers' Guide to Periodical Literature to locate articles of general interest related to its information…”
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