Search Results - "Davis, Alicia M"
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Small molecule-mediated allosteric activation of the base excision repair enzyme 8-oxoguanine DNA glycosylase and its impact on mitochondrial function
Published in Scientific reports (29-08-2022)“…8-Oxoguanine DNA glycosylase (OGG1) initiates base excision repair of the oxidative DNA damage product 8-oxoguanine. OGG1 is bifunctional; catalyzing glycosyl…”
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microRNA-142 guards against autoimmunity by controlling Treg cell homeostasis and function
Published in PLoS biology (01-02-2022)“…Regulatory T (Treg) cells are critical in preventing aberrant immune responses. Posttranscriptional control of gene expression by microRNA (miRNA) has recently…”
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Harnessing Rift Valley fever virus NSs gene for cancer gene therapy
Published in Cancer gene therapy (01-10-2022)“…One of the greatest challenges in the treatment of cancer is tumor heterogeneity which results in differential responses to chemotherapy and drugs that work…”
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Identification of influenza A nucleoprotein body domain residues essential for viral RNA expression expose antiviral target
Published in Virology journal (07-02-2017)“…Influenza A virus is controlled with yearly vaccination while emerging global pandemics are kept at bay with antiviral medications. Unfortunately, influenza A…”
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Emerging antiviral resistant strains of influenza A and the potential therapeutic targets within the viral ribonucleoprotein (vRNP) complex
Published in Virology journal (16-09-2014)“…Emerging antiviral resistant strains of influenza A virus are greatly limiting the therapies available to stop aggressive infections. Genome changes that…”
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Molecular modeling of polymer-clay nanocomposite precursors: Lysine in montmorillonite interlayers
Published in Journal of computational chemistry (30-04-2008)“…The layered structure of clays with interlayer cations leads to unique chemical and mechanical properties, which have been capitalized on in the field of…”
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7
microRNA-142 guards against autoimmunity by controlling T.sub.reg cell homeostasis and function
Published in PLoS biology (18-02-2022)“…Regulatory T (T.sub.reg) cells are critical in preventing aberrant immune responses. Posttranscriptional control of gene expression by microRNA (miRNA) has…”
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Small Molecule Ogg1 Activators Ameliorate mtDNA Oxidation and Promote Cell Health
Published in The FASEB journal (01-04-2016)“…Abstract only Chronic obstructive pulmonary disease (COPD) is characterized by progressive airflow limitation, loss of the alveolar unit, and increased levels…”
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Molecular modeling of polymer-clay nanocomposite precursors: Lysine in montmorillonite interlayers 4
Published in Journal of computational chemistry (30-04-2008)“…The layered structure of clays with interlayer cations leads to unique chemical and mechanical properties, which have been capitalized on in the field of…”
Get full text
Journal Article