Search Results - "Davio, C"
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Coumarins: old compounds with novel promising therapeutic perspectives
Published in Current medicinal chemistry (01-05-2010)“…Natural as well as synthetic coumarins have recently drawn much attention due to its broad pharmacological activities. Many coumarins and their derivatives…”
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The xenobiotic transporter ABCC4 /MRP4 promotes epithelial mesenchymal transition in pancreatic cancer
Published in Frontiers in pharmacology (24-07-2024)“…The xenobiotic transporter /MRP4 is highly expressed in pancreatic ductal adenocarcinoma (PDAC) and correlates with a more aggressive phenotype and metastatic…”
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Multidrug transporter MRP4/ABCC4 as a key determinant of pancreatic cancer aggressiveness
Published in Scientific reports (26-08-2020)“…Recent findings show that MRP4 is critical for pancreatic ductal adenocarcinoma (PDAC) cell proliferation. Nevertheless, the significance of MRP4 protein…”
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MRP4-mediated cAMP efflux is essential for mouse spermatozoa capacitation
Published in Journal of cell science (26-07-2019)“…Mammalian spermatozoa must undergo biochemical and structural changes to acquire the capacity for fertilization, in a process known as capacitation. Activation…”
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Fibronectin induces capacitation-associated events through the endocannabinoid system in bull sperm
Published in Theriogenology (01-09-2020)“…Mammalian ejaculated spermatozoa must undergo a series of changes in the female reproductive tract, collectively called capacitation, in order to fertilize the…”
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Melanocortin 4 receptor constitutive activity inhibits l-type voltage-gated calcium channels in neurons
Published in Neuroscience (27-03-2017)“…Highlights • We found that MC4R constitutive activity inhibits specifically CaV 1.2/1.3 and CaV 2.1 subtypes of CaV in a chronic manner. • Agonist-driven and…”
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P-020Targeting multidrug resistance - associated protein 4 (MRP4/ABCC4) in pancreatic cancer
Published in Annals of oncology (01-06-2016)Get full text
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Iron and holotransferrin induce cAMP-dependent differentiation of Schwann cells
Published in Neurochemistry international (01-10-2012)“…► We describe the effect of iron on myelin proteins in Schwann cells. ► We describe that iron promotes cAMP increase. ► We describe that iron promotes CREB…”
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Apotransferrin induces cAMP/CREB pathway and cell cycle exit in immature oligodendroglial cells
Published in Journal of neuroscience research (01-11-2004)“…We have demonstrated previously that a single intracranial injection of apotransferrin (aTf) in neonatal rats increases myelination and accelerates…”
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H1 and H2 histamine receptors in N-nitroso-N-methylurea (NMU)-induced carcinomas with atypical coupling to signal transducers
Published in Biochemical pharmacology (29-06-1995)“…Two specific binding sites for histamine were characterized in the cell membrane of N-nitroso-N-methylurea (NMU)-induced tumors. The first one, with higher…”
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H1 and H2 histamine receptors mediate the production of inositol phosphates but not cAMP in human breast epithelial cells
Published in Inflammation research (01-01-2002)“…In the present work we studied the H1 and H2 histamine receptor expression and function in HBL-100 and MCF-10A cells, derived from non-tumorigenic human breast…”
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Induction of mammary tumors in rat by intraperitoneal injection of NMU: histopathology and estral cycle influence
Published in Cancer letters (11-11-1994)“…In order to obtain an experimental model we induced mammary tumors in female Sprague-Dawley rats. The carcinogen N-nitroso-N-methylurea (NMU) was injected…”
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Effect of tamoxifen on intraperitoneal N-nitroso- N-methylurea induced tumors
Published in Cancer letters (27-02-1996)“…The effect of tamoxifen (TAM) was evaluated on a mammary tumor model induced in Sprague-Dawley rats by intraperitoneal administration of three N-nitroso-…”
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An experimental model of diabetes and cancer in rats
Published in European journal of cancer (1990) (01-05-1998)“…The aim of this study was to develop an experimental model for the study of cancer associated with diabetes. For diabetes induction, Sprague–Dawley rats were…”
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P-020 Targeting multidrug resistance – associated protein 4 (MRP4/ABCC4) in pancreatic cancer
Published in Annals of oncology (01-06-2016)Get full text
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Atypical association of H1 and H2 histamine receptors with signal transduction pathways during multistage mouse skin carcinogenesis
Published in Inflammation research (01-08-1997)“…In the present work we studied the association of histamine receptors with second messengers during multistage carcinogenesis in Sencar mice skin. 96 Sencar…”
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Tiotidine, a classical H 2 -antagonist, presents characteristics of an inverse agonist in U937 cell line
Published in Inflammation research (02-12-1998)Get full text
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Tiotidine, a classical H2-antagonist, presents characteristics of an inverse agonist in U937 cell line
Published in Inflammation research (1998)Get full text
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Atypical association of H 1 and H 2 histamine receptors with signal transduction pathways during multistage mouse skin carcinogenesis
Published in Inflammation research (01-08-1997)Get full text
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