Search Results - "Davies, Robert D"

Cubanes in Medicinal Chemistry: Synthesis of Functionalized Building Blocks by Wlochal, Joanna, Davies, Robert D. M, Burton, Jonathan

“…A collection of novel, pharma­ceutically relevant cubane-containing molecules has been prepared from the commercially available cubane-1,4-di­methyl­ester. A…”
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Tricyclic IndazolesA Novel Class of Selective Estrogen Receptor Degrader Antagonists by Scott, James S, Bailey, Andrew, Buttar, David, Carbajo, Rodrigo J, Curwen, Jon, Davey, Paul R. J, Davies, Robert D. M, Degorce, Sébastien L, Donald, Craig, Gangl, Eric, Greenwood, Ryan, Groombridge, Sam D, Johnson, Tony, Lamont, Scott, Lawson, Mandy, Lister, Andrew, Morrow, Christopher J, Moss, Thomas A, Pink, Jennifer H, Polanski, Radoslaw

“…Herein, we report the identification and synthesis of a series of tricyclic indazoles as a novel class of selective estrogen receptor degrader antagonists…”
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Formal Synthesis of Merrilactone A Using a Domino Cyanide 1,4-Addition–Aldol Cyclization by Nazef, Naim, Davies, Robert D. M, Greaney, Michael F

“…A formal synthesis of merrilactone A has been completed using a domino 1,4-addition–aldol process as the key step. Both iodo- and cyano-1,4-addition–aldol…”
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ECHO "Bootcamp": An Innovative Training Model to Onboard Providers in the Care of Gender Diverse Patients by Hoffner-Heinike, Alexander, Iwamoto, Sean J, Saxon, David R, Cogdall, Nicholas A, Davies, Robert D, Lee, Rita S, Chiappone, Alethea, Thomas, John F, Rothman, Micol S

“…Extension for Community Health Outcomes (ECHO) is a model of continuing medical education meant to connect academic medical center-based specialists with…”
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Randomized Controlled Trial of Osmotic-Release Methylphenidate With Cognitive-Behavioral Therapy in Adolescents With Attention-Deficit/Hyperactivity Disorder and Substance Use Disorders by Riggs, Paula D., M.D, Winhusen, Theresa, Ph.D, Davies, Robert D., M.D, Leimberger, Jeffrey D., Ph.D, Mikulich-Gilbertson, Susan, Ph.D, Klein, Constance, L.C.S.W, Macdonald, Marilyn, B.A, Lohman, Michelle, R.N, Bailey, Genie L., M.D, Haynes, Louise, M.S.W, Jaffee, William B., Ph.D, Haminton, Nancy, MPA, Hodgkins, Candace, Ph.D, Whitmore, Elizabeth, Ph.D, Trello-Rishel, Kathlene, M.D, Tamm, Leanne, Ph.D, Acosta, Michelle C., Ph.D, Royer-Malvestuto, Charlotte, M.Ed, Subramaniam, Geetha, M.D, Fishman, Marc, M.D, Holmes, Beverly W., M.S.W, Kaye, Mary Elyse, B.S.N, Vargo, Mark A., Ph.D, Woody, George E., M.D, Nunes, Edward V., M.D, Liu, David, M.D

“…Objective To evaluate the efficacy and safety of osmotic-release methylphenidate (OROS-MPH) compared with placebo for attention-deficit/hyperactivity disorder…”
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Gender-affirming hormone therapy, mental health, and surgical considerations for aging transgender and gender diverse adults by Iwamoto, Sean J., Defreyne, Justine, Kaoutzanis, Christodoulos, Davies, Robert D., Moreau, Kerrie L., Rothman, Micol S.

“…As the transgender and gender diverse (TGD) population ages, more transfeminine and transmasculine individuals present to clinic to initiate or continue their…”
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Identification, Optimization, and Pharmacology of Acylurea GHS-R1a Inverse Agonists by McCoull, William, Barton, Peter, Brown, Alastair J. H, Bowker, Suzanne S, Cameron, Jennifer, Clarke, David S, Davies, Robert D. M, Dossetter, Alexander G, Ertan, Anne, Fenwick, Mark, Green, Clive, Holmes, Jane L, Martin, Nathaniel, Masters, David, Moore, Jane E, Newcombe, Nicholas J, Newton, Claire, Pointon, Helen, Robb, Graeme R, Sheldon, Christopher, Stokes, Stephen, Morgan, David

“…Ghrelin plays a major physiological role in the control of food intake, and inverse agonists of the ghrelin receptor (GHS-R1a) are widely considered to offer…”
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Tetrahydroisoquinoline Phenols: Selective Estrogen Receptor Downregulator Antagonists with Oral Bioavailability in Rat by Scott, James S, Bailey, Andrew, Davies, Robert D. M, Degorce, Sébastien L, MacFaul, Philip A, Gingell, Helen, Moss, Thomas, Norman, Richard A, Pink, Jennifer H, Rabow, Alfred A, Roberts, Bryan, Smith, Peter D

“…A series of tetrahydroisoquinoline phenols was modified to give an estrogen receptor downregulator-antagonist profile. Optimization around the core, alkyl side…”
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Identification, optimisation and in vivo evaluation of oxadiazole DGAT-1 inhibitors for the treatment of obesity and diabetes by McCoull, William, Addie, Matthew S., Birch, Alan M., Birtles, Susan, Buckett, Linda K., Butlin, Roger J., Bowker, Suzanne S., Boyd, Scott, Chapman, Stephen, Davies, Robert D.M., Donald, Craig S., Green, Clive P., Jenner, Chloe, Kemmitt, Paul D., Leach, Andrew G., Moody, Graeme C., Morentin Gutierrez, Pablo, Newcombe, Nicholas J., Nowak, Thorsten, Packer, Martin J., Plowright, Alleyn T., Revill, John, Schofield, Paul, Sheldon, Chris, Stokes, Steve, Turnbull, Andrew V., Wang, Steven J.Y., Whalley, David P., Matthew Wood, J.

“…A novel series of DGAT-1 inhibitors was discovered from an oxadiazole amide high throughput screening (HTS) hit. Optimisation of potency and ligand…”
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Discovery and Optimization of Pyrrolopyrimidine Inhibitors of Interleukin‑1 Receptor Associated Kinase 4 (IRAK4) for the Treatment of Mutant MYD88L265P Diffuse Large B‑Cell Lymphoma by Scott, James S, Degorce, Sébastien L, Anjum, Rana, Culshaw, Janet, Davies, Robert D. M, Davies, Nichola L, Dillman, Keith S, Dowling, James E, Drew, Lisa, Ferguson, Andrew D, Groombridge, Sam D, Halsall, Christopher T, Hudson, Julian A, Lamont, Scott, Lindsay, Nicola A, Marden, Stacey K, Mayo, Michele F, Pease, J. Elizabeth, Perkins, David R, Pink, Jennifer H, Robb, Graeme R, Rosen, Alan, Shen, Minhui, McWhirter, Claire, Wu, Dedong

“…Herein we report the optimization of a series of pyrrolopyrimidine inhibitors of interleukin-1 receptor associated kinase 4 (IRAK4) using X-ray crystal…”
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Transgender Mental Health by Davies, Robert D

“…Davies reviews Transgender Mental Health by Eric Yarbrough…”
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Total Synthesis of the Callipeltoside Aglycon by Paterson, Ian, Davies, Robert D. M., Marquez, Rodolfo

“…Following macrolactonization, a Sonogashira coupling leads efficiently from 1 and 2 to the aglycon of the structurally unique cytotoxic macrolide…”
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Stereocontrolled Total Synthesis of (−)-Callipeltoside A by Paterson, Ian, Davies, Robert D. M, Heimann, Annekatrin C, Marquez, Rodolfo, Meyer, Arndt

“…A highly stereocontrolled total synthesis of the cytotoxic macrolide (−)-callipeltoside A has been achieved in 23 steps (4.8% overall). Notable features…”
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Gender-Affirming Hormone Use in Transgender Individuals: Impact on Behavioral Health and Cognition by Nguyen, Hillary B., Chavez, Alexis M., Lipner, Emily, Hantsoo, Liisa, Kornfield, Sara L., Davies, Robert D., Epperson, C. Neill

“…Purpose of Review With increasing numbers of transgender and gender non-binary individuals presenting for care, knowing how to elucidate the mental health and…”
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Gender Minority Stress, Depression, and Anxiety in a Transgender High School Student by Davies, Robert D, Kessel, Barbara

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The (Slow) Depathologizing of Gender Incongruence by Davies, Robert D., Davies, Madeline E.

“…Psychiatric nosology has at times mirrored cultural mores and societal values, pathologizing behaviors seen at the time to be either immoral or outside the…”
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Providing supportive transgender mental health care: A systemized narrative review of patient experiences, preferences, and outcomes by Panchal, Zoë, Piper, Christi, Whitmore, Charles, Davies, Robert D.

“…Transgender populations have high rates of many mental health diagnoses, but often delay or avoid mental health care due to prior poor experiences or fear of…”
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Wading Through the Flood of Nontraditional Therapies by Davies, Robert D

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A Four-Week Reflective Writing Program in the Psychiatry Clerkship: Testing Effects on Reflective Capacity by Whitmore, Charles A., Sakai, Joseph, Mikulich-Gilbertson, Susan K., Davies, Robert D.

“…Objective Reflective capacity is the ability to review and reconstruct the importance, emotional impact, and outcomes of an experience to give it added meaning…”
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Preliminary Evidence on the Effectiveness of Psychological Treatments Delivered at a University Counseling Center by Minami, Takuya, Davies, D. Robert, Tierney, Sandra Callen, Bettmann, Joanna E, McAward, Scott M, Averill, Lynnette A, Huebner, Lois A, Weitzman, Lauren M, Benbrook, Amy R, Serlin, Ronald C, Wampold, Bruce E

“…Treatment data from a university counseling center (UCC) that utilized the Outcome Questionnaire-45.2 (OQ-45; M. J. Lambert et al., 2004 ), a self-report…”
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