Search Results - "Davies, Q"

Autocatalytic Cleavage of the EMR2 Receptor Occurs at a Conserved G Protein-coupled Receptor Proteolytic Site Motif by Lin, Hsi-Hsien, Chang, Gin-Wen, Davies, John Q, Stacey, Martin, Harris, James, Gordon, Siamon

“…Post-translational cleavage at the G protein-coupled receptor proteolytic site (GPS) has been demonstrated in many class B2 G protein-coupled receptors as well…”
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The epidermal growth factor–like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans by Stacey, Martin, Chang, Gin-Wen, Davies, John Q., Kwakkenbos, Mark J., Sanderson, Ralph D., Hamann, Jörg, Gordon, Siamon, Lin, Hsi-Hsien

“…Using multivalent protein probes, an evolutionarily conserved endogenous ligand for EMR2, a human myeloid cell–restricted EGF-TM7 receptor, was identified on…”
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One‐Pot, Three‐Component Sulfonimidamide Synthesis Exploiting the Sulfinylamine Reagent N‐Sulfinyltritylamine, TrNSO by Davies, Thomas Q., Hall, Adrian, Willis, Michael C.

“…Sulfonimidamides are increasingly important molecules in medicinal chemistry and agrochemistry, but their preparation requires lengthy synthetic sequences,…”
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Rediscovering Sulfinylamines as Reagents for Organic Synthesis by Davies, Thomas Q., Willis, Michael C.

“…Sulfinylamines (R−N=S=O), monoaza analogues of sulfur dioxide, have been known for well over a century, and their reactivity as sulfur electrophiles and in…”
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Cervical cancer still presents symptomatically 20 years after the introduction of a structured national screening programme by Myriokefalitaki, E., Potdar, N., Barnfield, L., Davies, Q., Moss, E. L.

“…Objective To investigate the pattern of presentation of cervical cancer and to identify the characteristics of women who present symptomatically with cervical…”
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Ligation of the adhesion-GPCR EMR2 regulates human neutrophil function by Yona, Simon, Lin, Hsi-Hsien, Dri, Pietro, Davies, John Q, Hayhoe, Richard P.G, Lewis, Sion M, Heinsbroek, Sigrid E.M, Brown, K. Alun, Perretti, Mauro, Hamann, Jörg, Treacher, David F, Gordon, Siamon, Stacey, Martin

“…At present, ~150 different members of the adhesion-G protein-coupled receptor (GPCR) family have been identified in metazoans. Surprisingly, very little is…”
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Nickel-Catalyzed Enantioselective Coupling of Aldehydes and Electron-Deficient 1,3-Dienes Following an Inverse Regiochemical Course by Davies, Thomas Q., Kim, Jae Yeon, Fürstner, Alois

“…The nickel catalyzed reductive coupling of aldehydes with sorbate esters and related electron-deficient 1,3-dienes are known in the literature to occur at the…”
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Modular Sulfondiimine Synthesis Using a Stable Sulfinylamine Reagent by Zhang, Ze-Xin, Davies, Thomas Q, Willis, Michael C

“…Sulfondiiminesthe double aza-analogues of sulfoneshold significant potential as leads in discovery chemistry, yet their application in this arena has been…”
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A Silyl Sulfinylamine Reagent Enables the Modular Synthesis of Sulfonimidamides via Primary Sulfinamides by Ding, Mingyan, Zhang, Ze-Xin, Davies, Thomas Q, Willis, Michael C

“…A new N-silyl sulfinylamine reagent allows the rapid preparation of a broad range of (hetero)­aryl, alkenyl, and alkyl primary sulfinamides, using Grignard,…”
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Primary Sulfonamide Synthesis Using the Sulfinylamine Reagent N‑Sulfinyl‑O‑(tert-butyl)hydroxylamine, t‑BuONSO by Davies, Thomas Q, Tilby, Michael J, Skolc, David, Hall, Adrian, Willis, Michael C

“…Sulfonamides have played a defining role in the history of drug development and continue to be prevalent today. In particular, primary sulfonamides are common…”
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Harnessing Sulfinyl Nitrenes: A Unified One-Pot Synthesis of Sulfoximines and Sulfonimidamides by Davies, Thomas Q, Tilby, Michael J, Ren, Jack, Parker, Nicholas A, Skolc, David, Hall, Adrian, Duarte, Fernanda, Willis, Michael C

“…Sulfoximines and sulfonimidamides are promising compounds for medicinal and agrochemistry. As monoaza analogues of sulfones and sulfonamides, respectively,…”
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Changes in the treatment of endometrial cancer by Faust, G, Davies, Q, Symonds, P

“…Please cite this paper as: Faust G, Davies Q, Symonds P. Changes in the treatment of endometrial cancer. BJOG 2010;117:1043–1046…”
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Nickel-Catalyzed Enantioselective Synthesis of Pre-Differentiated Homoallylic syn- or anti-1,2-Diols from Aldehydes and Dienol Ethers by Davies, Thomas Q, Murphy, John J, Dousset, Maxime, Fürstner, Alois

“…Nickel catalysis allied with cyclodiphosphazane or VAPOL-derived phosphoramidite ligands provides selective access to monoprotected vicinal diols by reductive…”
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The Role of Receptor Oligomerization in Modulating the Expression and Function of Leukocyte Adhesion-G Protein-coupled Receptors by Davies, John Q., Chang, Gin-Wen, Yona, Simon, Gordon, Siamon, Stacey, Martin, Lin, Hsi-Hsien

“…The human leukocyte adhesion-G protein-coupled receptors (GPCRs), the epidermal growth factor (EGF)-TM7 proteins, are shown here to function as homo- and…”
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Frontispiece: Rediscovering Sulfinylamines as Reagents for Organic Synthesis by Davies, Thomas Q., Willis, Michael C.

“…Recent applications of N‐sulfinylamines: The use of N‐sulfinylamines (R−N=S=O) in sulfoximine and sulfonimidamide synthesis, heterocycle formation and…”
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CD312, the human adhesion-GPCR EMR2, is differentially expressed during differentiation, maturation, and activation of myeloid cells by Chang, Gin-Wen, Davies, John Q., Stacey, Martin, Yona, Simon, Bowdish, Dawn M.E., Hamann, Jörg, Chen, Tse-Ching, Lin, Chun-Yen, Gordon, Siamon, Lin, Hsi-Hsien

“…EMR2/CD312 is a member of the adhesion-GPCR family that contains extracellular EGF-like domains. Previously it has been shown to interact with chondroitin…”
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A distinctive vulval fibroma of so-called prepubertal type in a postmenopausal patient by Ajibona, O O, Richards, C J, Davies, Q

“…The case of a 65-year-old female patient who has had a large right vulval mass for over 30 years is reported here. The mass was excised, but the hypocellular…”
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“So Take This Magic Flute and Blow. It Will Protect Us As We Go”: Impempe Yomlingo (2007–11) and South Africa’s Ongoing Transition by Davies, Sheila Boniface, Davies, J. Q

“…Davies and Davies examine the many ways in which Impempe Yomlingo performs transition. Fraught political debates regarding the ongoing transition from…”
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Ectopic prolactin secretion secondary to an ovarian tumour by Gururaj, Sowmya, Nisal, K, Davies, Q, Deen, S, McNally, P G

“…Summary Ectopic hormone secretion is a well-recognised phenomenon; however, ectopic prolactin secretion is exceptionally rare. Hoffman and colleagues reported…”
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Isolation and culture of murine macrophages by Davies, John Q, Gordon, Siamon

“…The two most convenient sources of primary murine macrophages are the bone marrow and the peritoneal cavity. Resident peritoneal macrophages can readily be…”
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