Search Results - "Davies, Paul C W"

A Bacterium That Can Grow by Using Arsenic Instead of Phosphorus by Wolfe-Simon, Felisa, Blum, Jodi Switzer, Kulp, Thomas R., Gordon, Gwyneth W., Hoeft, Shelley E., Pett-Ridge, Jennifer, Stolz, John F., Webb, Samuel M., Weber, Peter K., Davies, Paul C. W., Anbar, Ariel D., Oremland, Ronald S.

“…Life is mostly composed of the elements carbon, hydrogen, nitrogen, oxygen, sulfur, and phosphorus. Although these six elements make up nucleic acids,…”
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Isotropic 3D nuclear morphometry of normal, fibrocystic and malignant breast epithelial cells reveals new structural alterations by Nandakumar, Vivek, Kelbauskas, Laimonas, Hernandez, Kathryn F, Lintecum, Kelly M, Senechal, Patti, Bussey, Kimberly J, Davies, Paul C W, Johnson, Roger H, Meldrum, Deirdre R

“…Grading schemes for breast cancer diagnosis are predominantly based on pathologists' qualitative assessment of altered nuclear structure from 2D brightfield…”
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Ancient hot and cold genes and chemotherapy resistance emergence by Wu, Amy, Zhang, Qiucen, Lambert, Guillaume, Khin, Zayar, Gatenby, Robert A., Kim, Hyunsung John, Pourmand, Nader, Bussey, Kimberly, Davies, Paul C. W., Sturm, James C., Austin, Robert H.

“…We use a microfabricated ecology with a doxorubicin gradient and population fragmentation to produce a strong Darwinian selective pressure that drives forward…”
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Electron-mirror duality and thermality by Ievlev, Evgenii, Good, Michael R. R., Davies, Paul C. W.

“…Classical electromagnetic radiation from moving point charges is foundational, but the thermal dynamics responsible for classical acceleration temperature are…”
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Formal Definitions of Unbounded Evolution and Innovation Reveal Universal Mechanisms for Open-Ended Evolution in Dynamical Systems by Adams, Alyssa, Zenil, Hector, Davies, Paul C. W., Walker, Sara Imari

“…Open-ended evolution (OEE) is relevant to a variety of biological, artificial and technological systems, but has been challenging to reproduce in silico . Most…”
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Physical Universality, State-Dependent Dynamical Laws and Open-Ended Novelty by Adams, Alyssa, Berner, Angelica, Davies, Paul, Walker, Sara

“…A major conceptual step forward in understanding the logical architecture of living systems was advanced by von Neumann with his universal constructor, a…”
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Quantum non-barking dogs by Imari Walker, Sara, Davies, Paul C W, Samantray, Prasant, Aharonov, Yakir

“…Quantum weak measurements with states both pre- and post-selected offer a window into a hitherto neglected sector of quantum mechanics. A class of such systems…”
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The algorithmic origins of life by Walker, Sara Imari, Davies, Paul C. W.

“…Although it has been notoriously difficult to pin down precisely what is it that makes life so distinctive and remarkable, there is general agreement that its…”
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The informational architecture of the cell by Walker, Sara Imari, Kim, Hyunju, Davies, Paul C. W.

“…We compare the informational architecture of biological and random networks to identify informational features that may distinguish biological networks from…”
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Cancer progression as a sequence of atavistic reversions by Lineweaver, Charles H., Bussey, Kimberly J., Blackburn, Anneke C., Davies, Paul C. W.

“…It has long been recognized that cancer onset and progression represent a type of reversion to an ancestral quasi‐unicellular phenotype. This general concept…”
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Reverting to single-cell biology: The predictions of the atavism theory of cancer by Bussey, Kimberly J., Davies, Paul C.W.

“…Cancer or cancer-like phenomena pervade multicellular life, implying deep evolutionary roots. Many of the hallmarks of cancer recapitulate unicellular…”
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Response to Comments on “A Bacterium That Can Grow Using Arsenic Instead of Phosphorus” by Wolfe-Simon, Felisa, Blum, Jodi Switzer, Kulp, Thomas R., Gordon, Gwyneth W., Hoeft, Shelley E., Pett-Ridge, Jennifer, Stolz, John F., Webb, Samuel M., Weber, Peter K., Davies, Paul C. W., Anbar, Ariel D., Oremland, Ronald S.

“…Concerns have been raised about our recent study suggesting that arsenic (As) substitutes for phosphorus in major biomolecules of a bacterium that tolerates…”
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Infrared Acceleration Radiation by Good, Michael R. R., Davies, Paul C. W.

“…We present an exactly soluble electron trajectory that permits an analysis of the soft (deep infrared) radiation emitted, the existence of which has been…”
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Ancestral gene regulatory networks drive cancer by Bussey, Kimberly J., Cisneros, Luis H., Lineweaver, Charles H., Davies, Paul C. W.

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Astrobiological Implications of Interstellar Material in the Solar System by Davies, Paul C W, Worden, S Peter

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Targeting cancer's weaknesses (not its strengths): Therapeutic strategies suggested by the atavistic model by Lineweaver, Charles H., Davies, Paul C. W., Vincent, Mark D.

“…In the atavistic model of cancer progression, tumor cell dedifferentiation is interpreted as a reversion to phylogenetically earlier capabilities. The more…”
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Self-organization and entropy reduction in a living cell by Davies, Paul C.W., Rieper, Elisabeth, Tuszynski, Jack A.

“…In this paper we discuss the entropy and information aspects of a living cell. Particular attention is paid to the information gain on assembling and…”
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Signatures of a shadow biosphere by Davies, Paul C W, Benner, Steven A, Cleland, Carol E, Lineweaver, Charles H, McKay, Christopher P, Wolfe-Simon, Felisa

“…Astrobiologists are aware that extraterrestrial life might differ from known life, and considerable thought has been given to possible signatures associated…”
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Cancer as a dynamical phase transition by Davies, Paul Cw, Demetrius, Lloyd, Tuszynski, Jack A

“…This paper discusses the properties of cancer cells from a new perspective based on an analogy with phase transitions in physical systems. Similarities in…”
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The Quantum Vacuum of Spacetime with a Fundamental Length by Davies, Paul C. W, Tee, Philip

“…Phys. Rev. D 110, 025009 2024 A quantum theory of gravity implies a fine-grained structure of spacetime, which can be conveniently modeled as some form of…”
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