Search Results - "Davies, Melanie J"

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    Type 2 diabetes by Chatterjee, Sudesna, MD, Khunti, Kamlesh, Prof, Davies, Melanie J, Prof

    Published in The Lancet (British edition) (03-06-2017)
    “…Summary 415 million people live with diabetes worldwide, and an estimated 193 million people have undiagnosed diabetes. Type 2 diabetes accounts for more than…”
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    Journal Article
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    Pathophysiology of type 1 and type 2 diabetes mellitus: a 90-year perspective by Zaccardi, Francesco, Webb, David R, Yates, Thomas, Davies, Melanie J

    Published in Postgraduate medical journal (01-02-2016)
    “…Diabetes mellitus is a complex metabolic disorder associated with an increased risk of microvascular and macrovascular disease; its main clinical…”
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    Journal Article Book Review
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    Diabetic peripheral neuropathy: advances in diagnosis and strategies for screening and early intervention by Selvarajah, Dinesh, Kar, Debasish, Khunti, Kamlesh, Davies, Melanie J, Scott, Adrian R, Walker, Jeremy, Tesfaye, Solomon

    Published in The lancet. Diabetes & endocrinology (01-12-2019)
    “…Diabetic peripheral neuropathy (DPN) is a common complication of both type 1 and 2 diabetes. It is a leading cause of lower-limb amputation and disabling…”
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    Efficacy and safety of glucagon‐like peptide‐1 receptor agonists in type 2 diabetes: A systematic review and mixed‐treatment comparison analysis by Htike, Zin Z., Zaccardi, Francesco, Papamargaritis, Dimitris, Webb, David R., Khunti, Kamlesh, Davies, Melanie J.

    Published in Diabetes, obesity & metabolism (01-04-2017)
    “…Aims To compare efficacy and safety of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) in people with type 2 diabetes. Materials and methods We…”
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    Journal Article
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    Healthy lifestyle and life expectancy in people with multimorbidity in the UK Biobank: A longitudinal cohort study by Chudasama, Yogini V, Khunti, Kamlesh, Gillies, Clare L, Dhalwani, Nafeesa N, Davies, Melanie J, Yates, Thomas, Zaccardi, Francesco

    Published in PLoS medicine (01-09-2020)
    “…Whether a healthy lifestyle impacts longevity in the presence of multimorbidity is unclear. We investigated the associations between healthy lifestyle and life…”
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    Journal Article
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    Uses and Limitations of the Restricted Mean Survival Time: Illustrative Examples From Cardiovascular Outcomes and Mortality Trials in Type 2 Diabetes by Kloecker, David E, Davies, Melanie J, Khunti, Kamlesh, Zaccardi, Francesco

    Published in Annals of internal medicine (21-04-2020)
    “…The restricted mean survival time (RMST) has been advocated as an alternative or a supplement to the hazard ratio for reporting the effect of an intervention…”
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    Journal Article
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    Impact of COVID-19 on routine care for chronic diseases: A global survey of views from healthcare professionals by Chudasama, Yogini V., Gillies, Clare L., Zaccardi, Francesco, Coles, Briana, Davies, Melanie J., Seidu, Samuel, Khunti, Kamlesh

    “…Routine care for chronic disease is an ongoing major challenge. We aimed to evaluate the global impact of COVID-19 on routine care for chronic diseases. An…”
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    Journal Article
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    Physical activity, multimorbidity, and life expectancy: a UK Biobank longitudinal study by Chudasama, Yogini V, Khunti, Kamlesh K, Zaccardi, Francesco, Rowlands, Alex V, Yates, Thomas, Gillies, Clare L, Davies, Melanie J, Dhalwani, Nafeesa N

    Published in BMC medicine (12-06-2019)
    “…Multimorbidity is an emerging public health priority. Physical activity (PA) is recommended as one of the main lifestyle behaviours, yet the benefits of PA for…”
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    Journal Article
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    The Effect of Glucagon-Like Peptide 1 Receptor Agonists on Weight Loss in Type 2 Diabetes: A Systematic Review and Mixed Treatment Comparison Meta-Analysis by Potts, Jessica E, Gray, Laura J, Brady, Emer M, Khunti, Kamlesh, Davies, Melanie J, Bodicoat, Danielle H

    Published in PloS one (29-06-2015)
    “…To determine the effects of glucagon-like peptide-1 receptor agonists compared with placebo and other anti-diabetic agents on weight loss in overweight or…”
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    Journal Article
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    Associations Between Sedentary Behaviors and Cognitive Function: Cross-Sectional and Prospective Findings From the UK Biobank by Bakrania, Kishan, Edwardson, Charlotte L, Khunti, Kamlesh, Bandelow, Stephan, Davies, Melanie J, Yates, Thomas

    Published in American journal of epidemiology (01-03-2018)
    “…Abstract We investigated the cross-sectional and prospective associations between different sedentary behaviors and cognitive function in a large sample of…”
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    Journal Article
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    Association between polypharmacy and falls in older adults: a longitudinal study from England by Dhalwani, Nafeesa N, Fahami, Radia, Sathanapally, Harini, Seidu, Sam, Davies, Melanie J, Khunti, Kamlesh

    Published in BMJ open (01-10-2017)
    “…ObjectivesAssess the longitudinal association between polypharmacy and falls and examine the differences in this association by different thresholds for…”
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    Journal Article
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    Promoting inclusion in clinical trials—a rapid review of the literature and recommendations for action by Bodicoat, Danielle H, Routen, Ash C, Willis, Andrew, Ekezie, Winifred, Gillies, Clare, Lawson, Claire, Yates, Thomas, Zaccardi, Francesco, Davies, Melanie J, Khunti, Kamlesh

    “…Abstract Background Without inclusion of diverse research participants, it is challenging to understand how study findings will translate into the real world…”
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    Journal Article
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    Sedentary time and markers of chronic low-grade inflammation in a high risk population by Henson, Joseph, Yates, Thomas, Edwardson, Charlotte L, Khunti, Kamlesh, Talbot, Duncan, Gray, Laura J, Leigh, Thomas M, Carter, Patrice, Davies, Melanie J

    Published in PloS one (29-10-2013)
    “…Sedentary behaviour has been identified as a distinct risk factor for several health outcomes. Nevertheless, little research has been conducted into the…”
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    Incorporating and interpreting regulatory guidance on estimands in diabetes clinical trials: The PIONEER 1 randomized clinical trial as an example by Aroda, Vanita R., Saugstrup, Trine, Buse, John B., Donsmark, Morten, Zacho, Jeppe, Davies, Melanie J.

    Published in Diabetes, obesity & metabolism (01-10-2019)
    “…Regulatory guidelines describe the use of estimands in designing and conducting clinical trials. Estimands ensure alignment of the objectives with the design,…”
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    Journal Article
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    Guideline recommendations and the positioning of newer drugs in type 2 diabetes care by Marx, Nikolaus, Davies, Melanie J, Grant, Peter J, Mathieu, Chantal, Petrie, John R, Cosentino, Francesco, Buse, John B

    Published in The lancet. Diabetes & endocrinology (01-01-2021)
    “…Cardiovascular outcome trials in patients with type 2 diabetes at high cardiovascular risk have led to remarkable advances in our understanding of the…”
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    Association of sedentary behaviour with metabolic syndrome: a meta-analysis by Edwardson, Charlotte L, Gorely, Trish, Davies, Melanie J, Gray, Laura J, Khunti, Kamlesh, Wilmot, Emma G, Yates, Thomas, Biddle, Stuart J H

    Published in PloS one (13-04-2012)
    “…In recent years there has been a growing interest in the relationship between sedentary behaviour (sitting) and health outcomes. Only recently have there been…”
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    Journal Article