Search Results - "Davies, Les"

The Challenge: Assessment of risks posed by systemic insecticides to hymenopteran pollinators: New perception when we move from laboratory via (semi‐)field to landscape scale testing? by Heimbach, Fred, Schmuck, Richard, Grünewald, Bernd, Campbell, Peter, Sappington, Keith, Steeger, Thomas, Davies, Les P.

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Guidance on setting of acute reference dose (ARfD) for pesticides by Solecki, Roland, Davies, Les, Dellarco, Vicki, Dewhurst, Ian, Raaij, Marcel van, Tritscher, Angelika

“…This paper summarises and extends the work developed over the last decade by the Joint FAO/WHO Meeting on Pesticide Residues (JMPR) for acute health risk…”
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The Long Ashton Legacy: Characterising United Kingdom West Country cider apples using a genotyping by targeted sequencing approach by Harper, Helen, Winfield, Mark O., Copas, Liz, Przewieslik‐Allen, Sacha A., Barker, Gary L. A., Burridge, Amanda, Hughes, Bob R., Davies, Les, Edwards, Keith J.

“…Societal Impact Statement The English West Country is the home of cider making, providing the region with jobs and industry, as well as cultural reference…”
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Gnome, sweet gnome by Davies, Les

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Inhibition of adenosine kinase and adenosine uptake in guinea-pig CNS tissue by halogenated tubercidin analogues by Davies, Les P, Cook, Alan F

“…Two halogenated analogues of tubercidin (7-deazaadenosine) viz. 5-iodotubercidin and 5′-deoxy-5-iodotubercidin, previously were shown to be potent inhibitors…”
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New imidazo[1,2-b]pyridazine ligands for peripheral-type benzodiazepine receptors on mitochondria and monocytes by Davies, L P, Barlin, G B, Selley, M L

“…Several 6-chloro-2,3-disubstituted imidazo[1,2-b]pyridazines, selected from a number of synthetic imidazo[1,2-b]pyridazines which lacked significant binding…”
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A purinergic component in the anticonvulsant action of carbamazepine? by Skeritt, J H, Davies, L P, Johnston, G A

“…The tricyclic anticonvulsant carbamazepine inhibited the binding of [3H]phenylisopropyladenosine (PIA) to rat brain membranes with a K1 value of 44 microM,…”
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Risk management options for endocrine disruptors in national and international programs by Lamb, J. C., Koëter, H. B. W. M., Becker, R., Gies, A., Davies, Les, Inoue, T., Jacobs, A., Lyons, G., Matsumoto, M., Timm, G.

“…This workshop was convened to address common issues and concerns associated with risk management of endocrine-disrupting chemicals (EDCs). The talks described…”
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Peripheral benzodiazepine binding sites in heart and their interaction with dipyridamole by Davies, L P, Huston, V

“…Specific binding of [3H]diazepam to rat and guinea-pig heart tissue has been found. These binding sites are similar to those in lung, liver, kidney and mast…”
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Fluoxetine-induced lung damage by Davies, L P

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Interactions of the anticonvulsant carbamazepine with adenosine receptors. 1. Neurochemical studies by Skerritt, J H, Davies, L P, Johnston, G A

“…At therapeutic concentrations the tricyclic anticonvulsant carbamazepine inhibited the binding of the adenosine analogue [3H]L-N6-phenylisopropyladenosine…”
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Substituted imidazo[1,2-b]pyridazines. New compounds with activity at central and peripheral benzodiazepine receptors by Davies, L P, Barlin, G B, Ireland, S J, Ngu, M M

“…A large range of substituted imidazo[1,2-b]pyridazines have been synthesized, and a number of potent ligands at central benzodiazepine (Bz) receptors on rat…”
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Studies on several pyrrolo[2,3-d]pyrimidine analogues of adenosine which lack significant agonist activity at A1 and A2 receptors but have potent pharmacological activity in vivo by Davies, L P, Baird-Lambert, J, Marwood, J F

“…5'-Deoxy-5-iodotubercidin was previously reported to cause potent muscle relaxation and hypothermia when injected i.p. into mice. In normotensive rats, i.v…”
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Questions Asked by Davies, Les, Sweet, Matthew

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Halogenated pyrrolopyrimidine analogues of adenosine from marine organisms: pharmacological activities and potent inhibition of adenosine kinase by Davies, L P, Jamieson, D D, Baird-Lambert, J A, Kazlauskas, R

“…Two novel halogenated pyrrolopyrimidine analogues of adenosine, isolated from marine sources, have been examined for pharmacological and biochemical…”
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Neurochemical Studies on Amino Acid Transmitters by Davies, Les Philip

“…Several neurochemical correlates of synapticallyactive amino acids, including high affinity, sodium-dependent uptake into brain slices, calcium-dependent…”
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Pyrazolo[3,4-d]pyrimidines as adenosine antagonists by Davies, L P, Chow, S C, Skerritt, J H, Brown, D J, Johnston, G A

“…A large number of nitrogen heterocycles structurally related to caffeine and theophylline have been tested for activity as adenosine antagonists. Preliminary…”
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Pyrazolo [3,4-d] pyrimidines, a new class of adenosine antagonists by Davies, L P, Brown, D J, Chow, S C, Johnston, G A

“…A variety of nitrogen heterocycles structurally related to caffeine and theophylline have been tested for activity as adenosine receptor antagonists…”
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Displacement of [3H] diazepam binding in rat brain by dipyridamole and by 1-methylisoguanosine, a marine natural product with muscle relaxant activity by Davies, L P, Cook, A F, Poonian, M, Taylor, K M

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Purines interact with 'central' but not 'peripheral' benzodiazepine binding sites by Skerritt, J H, Chen Chow, S, Johnston, G A, Davies, L P

“…The effects of several purines and the purine uptake inhibitor, dipyridamole, on the binding, to rat brain membranes, of 4 benzodiazepines with different…”
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