Search Results - "Davies, Kate V.L."

Diminished responses to IL‐13 by human monocytes differentiated in vitro: role of the IL‐13Rα1 chain and STAT6 by Hart, Prue H., Bonder, Claudine S., Balogh, Julianna, Dickensheets, Harold L., Vazquez, Nancy, Davies, Kate V. L., Finlay‐Jones, John J., Donnelly, Raymond P.

“…The primary IL‐13 receptor complex on human monocytes is believed to be a heterodimer comprised of the IL‐4Rα chain and the IL‐2Rγ chain (γc)‐like molecule,…”
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Inflammatory processes in a murine model of intra-abdominal abscess formation by Finlay‐Jones, John J., Davies, Kate V. L., Sturm, Lana P., Kenny, Peter A., Hart, Prue H.

“…Abscess formation has been viewed as a host defense strategy to contain the spread of infection. However, abscesses are also serious and life‐threatening…”
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IFN-gamma downregulates interleukin-4 functional activity on monocytes by multiple mechanisms by Bonder, Claudine S, Davies, Kate V L, Hosszu, Emma K, Finlay-Jones, John J, Hart, Prue H

“…Interleukin-4 (IL-4) has potent anti-inflammatory properties on monocytes and suppresses lipopolysaccharide (LPS)-induced tumor necrosis factor-alpha…”
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ENDOGENOUS INTERFERON-α PRODUCTION BY DIFFERENTIATING HUMAN MONOCYTES REGULATES EXPRESSION AND FUNCTION OF THE IL-2/IL-4 RECEPTOR γ CHAIN by Bonder, Claudine S., Davies, Kate V.L., Liu, Xiang, Hertzog, Paul J., Woodcock, Joanna M., Finlay-Jones, John J., Hart, Prue H.

“…In vitro monocyte-derived macrophages (MDMac) and synovial fluid macrophages from inflamed joints differ from monocytes in their responses to interleukin 4…”
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Characterization of IL-4 Receptor Components Expressed on Monocytes and Monocyte-derived Macrophages: Variation Associated with Differential Signaling by IL-4 by Bonder, Claudine S., Hart, Prue H., Davies, Kate V.L., Buriuy, Linda C., Finlay-Jones, John J., Woodcock, Joanna M.

“…Abstract The anti-inflammatory effects of IL-4 on activated monocytes differ from those on monocyte-derived macrophages (MDMac). While IL-4 suppresses…”
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