Search Results - "Davies, J A"

The Proteasome and Oxidative Stress in Alzheimer's Disease by Bonet-Costa, Vicent, Pomatto, Laura Corrales-Diaz, Davies, Kelvin J A

“…Alzheimer's disease is a neurodegenerative disorder that is projected to exceed more than 100 million cases worldwide by 2050. Aging is considered the primary…”
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Transplantation of specific human astrocytes promotes functional recovery after spinal cord injury by Davies, Stephen J A, Shih, Chung-Hsuan, Noble, Mark, Mayer-Proschel, Margot, Davies, Jeannette E, Proschel, Christoph

“…Repairing trauma to the central nervous system by replacement of glial support cells is an increasingly attractive therapeutic strategy. We have focused on the…”
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The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes by Pickering, Andrew M, Koop, Alison L, Teoh, Cheryl Y, Ermak, Gennady, Grune, Tilman, Davies, Kelvin J A

“…Oxidized cytoplasmic and nuclear proteins are normally degraded by the proteasome, but accumulate with age and disease. We demonstrate the importance of…”
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Clumped-isotope palaeothermometry and LA-ICP-MS U–Pb dating of lava-pile hydrothermal calcite veins by MacDonald, J. M., Faithfull, J. W., Roberts, N. M. W., Davies, A. J., Holdsworth, C. M., Newton, M., Williamson, S., Boyce, A., John, C. M.

“…Calcite veins are a common product of hydrothermal fluid circulation. Clumped-isotope palaeothermometry is a promising technique for fingerprinting the…”
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THE DEFLECTION OF THE TWO INTERACTING CORONAL MASS EJECTIONS OF 2010 MAY 23-24 AS REVEALED BY COMBINED IN SITU MEASUREMENTS AND HELIOSPHERIC IMAGING by LUGAZ, N, FARRUGIA, C. J, DAVIES, J. A, MÖSTL, C, DAVIS, C. J, ROUSSEV, I. I, TEMMER, M

“…In 2010 May 23-24, Solar Dynamics Observatory (SDO) observed the launch of two successive coronal mass ejections (CMEs), which were subsequently tracked by the…”
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Oxidative stress adaptation with acute, chronic, and repeated stress by Pickering, Andrew M., Vojtovich, Lesya, Tower, John, A. Davies, Kelvin J.

“…Oxidative stress adaptation, or hormesis, is an important mechanism by which cells and organisms respond to, and cope with, environmental and physiological…”
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A SELF-SIMILAR EXPANSION MODEL FOR USE IN SOLAR WIND TRANSIENT PROPAGATION STUDIES by DAVIES, J. A, HARRISON, R. A, SAVANI, N. P, PERRY, C. H, MÖSTL, C, LUGAZ, N, ROLLETT, T, DAVIS, C. J, CROTHERS, S. R, TEMMER, M, EYLES, C. J

“…Since the advent of wide-angle imaging of the inner heliosphere, a plethora of techniques have been developed to investigate the three-dimensional structure…”
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A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells by Guo, Lei, Li, Jia, Zeng, Hongxiang, Guzman, Anna G., Li, Tingting, Lee, Minjung, Zhou, Yubin, Goodell, Margaret A., Stephan, Clifford, Davies, Peter J. A., Dawson, Mark A, Sun, Deqiang, Huang, Yun

“…Primary and acquired drug resistance imposes a major threat to achieving optimized clinical outcomes during cancer treatment. Aberrant changes in epigenetic…”
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3-D ocean particle tracking modeling reveals extensive vertical movement and downstream interdependence of closed areas in the northwest Atlantic by Wang, S., Kenchington, E. L., Wang, Z., Yashayaev, I., Davies, A. J.

“…Novel 3-D passive particle tracking experiments were performed in the northwest Atlantic to elucidate connectivity among areas closed to protect vulnerable…”
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Speeds and Arrival Times of Solar Transients Approximated by Self-similar Expanding Circular Fronts by Möstl, C., Davies, J. A.

“…The NASA Solar TErrestrial RElations Observatory (STEREO) mission offered the possibility to forecast the arrival times, speeds, and directions of solar…”
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Food system actor perspectives on future-proofing European food systems through plant breeding by Stetkiewicz, S., Menary, J., Nair, A., Rufino, M., Fischer, A. R. H., Cornelissen, M., Guichaoua, A., Jorasch, P., Lemarié, S., Nanda, A. K., Wilhelm, R., Davies, J. A. C.

“…Crop improvement is a key innovation area in the pursuit of sustainable food systems. However, realising its potential requires integration of the needs and…”
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Free radical biology and medicine: it's a gas, man by Pryor, William A, Houk, Kendall N, Foote, Christopher S, Fukuto, Jon M, Ignarro, Louis J, Squadrito, Giuseppe L, Davies, Kelvin J A

“…We review gases that can affect oxidative stress and that themselves may be radicals. We discuss O(2) toxicity, invoking superoxide, hydrogen peroxide, and the…”
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Stereoscopic imaging of an Earth‐impacting solar coronal mass ejection: A major milestone for the STEREO mission by Davis, C. J., Davies, J. A., Lockwood, M., Rouillard, A. P., Eyles, C. J., Harrison, R. A.

“…We present stereoscopic images of an Earth‐impacting Coronal Mass Ejection (CME). The CME was imaged by the Heliospheric Imagers onboard the twin STEREO…”
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CMEs in the Heliosphere: I. A Statistical Analysis of the Observational Properties of CMEs Detected in the Heliosphere from 2007 to 2017 by STEREO/HI-1 by Harrison, R. A., Davies, J. A., Barnes, D., Byrne, J. P., Perry, C. H., Bothmer, V., Eastwood, J. P., Gallagher, P. T., Kilpua, E. K. J., Möstl, C., Rodriguez, L., Rouillard, A. P., Odstrčil, D.

“…We present a statistical analysis of coronal mass ejections (CMEs) imaged by the Heliospheric Imager (HI) instruments on board NASA’s twin-spacecraft STEREO…”
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The Heliospheric Imagers Onboard the STEREO Mission by Eyles, C. J., Harrison, R. A., Davis, C. J., Waltham, N. R., Shaughnessy, B. M., Mapson-Menard, H. C. A., Bewsher, D., Crothers, S. R., Davies, J. A., Simnett, G. M., Howard, R. A., Moses, J. D., Newmark, J. S., Socker, D. G., Halain, J.-P., Defise, J.-M., Mazy, E., Rochus, P.

“…Mounted on the sides of two widely separated spacecraft, the two Heliospheric Imager (HI) instruments onboard NASA’s STEREO mission view, for the first time,…”
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Mitochondrial biogenesis-associated factors underlie the magnitude of response to aerobic endurance training in rats by Marton, Orsolya, Koltai, Erika, Takeda, Masaki, Koch, Lauren Gerard, Britton, Steven L., Davies, Kelvin J. A., Boldogh, Istvan, Radak, Zsolt

“…Trainability is important in elite sport and in recreational physical activity, and the wide range for response to training is largely dependent on genotype…”
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Fingerprinting Kinetic Isotope Effects and Diagenetic Exchange Reactions Using Fluid Inclusion and Dual‐Clumped Isotope Analysis by Staudigel, P., Davies, A. J., Bernecker, M., Tagliavento, M., Lubbe, H. J. L., Nooitgedacht, C., Looser, N., Bernasconi, S. M., Vonhof, H., Fiebig, J.

“…Geochemical analyses of carbonate minerals yield multiple parameters which can be used to estimate the temperature and water composition at which they formed…”
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A synoptic view of solar transient evolution in the inner heliosphere using the Heliospheric Imagers on STEREO by Davies, J. A., Harrison, R. A., Rouillard, A. P., Sheeley Jr, N. R., Perry, C. H., Bewsher, D., Davis, C. J., Eyles, C. J., Crothers, S. R., Brown, D. S.

“…By exploiting data from the STEREO/heliospheric imagers (HI) we extend a well‐established technique developed for coronal analysis by producing time‐elongation…”
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Determining the Azimuthal Properties of Coronal Mass Ejections from Multi-Spacecraft Remote-Sensing Observations with STEREO SECCHI by Lugaz, N, Hernandez-Charpak, J. N, Roussev, I. I, Davis, C. J, Vourlidas, A, Davies, J. A

“…We discuss how simultaneous observations by multiple heliospheric imagers (HIs) can provide some important information about the azimuthal properties of…”
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First imaging of corotating interaction regions using the STEREO spacecraft by Rouillard, A. P., Davies, J. A., Forsyth, R. J., Rees, A., Davis, C. J., Harrison, R. A., Lockwood, M., Bewsher, D., Crothers, S. R., Eyles, C. J., Hapgood, M., Perry, C. H.

“…Plasma parcels are observed propagating from the Sun out to the large coronal heights monitored by the Heliospheric Imagers (HI) instruments onboard the NASA…”
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